anti-K(lysine) Acetyltransferase 8 (KAT8) Antikörper

KAT8 encodes a member of the MYST histone acetylase protein family. Zusätzlich bieten wir Ihnen K(lysine) Acetyltransferase 8 Kits (6) und K(lysine) Acetyltransferase 8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KAT8 310194 Q5XI06
KAT8 84148 Q9H7Z6
KAT8 67773 Q9D1P2
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Top anti-K(lysine) Acetyltransferase 8 Antikörper auf antikoerper-online.de

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-MYST1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-HMOF/MYST1(C-term) Pab (ABIN387971) in K562 cell line lysates (35 µg/lane). HMOF/MYST1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) (ABIN387971), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Maus Unkonjugiert ICC, IHC, ELISA, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
453,56 €
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Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYST1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Maus Unkonjugiert IF, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
440,00 €
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
442,32 €
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Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Maus Unkonjugiert ICC, IF, IHC (p), IHC, ELISA, WB 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details

KAT8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-K(lysine) Acetyltransferase 8 Antikörper

  1. Human Polyclonal KAT8 Primary Antibody für EIA, IHC (p) - ABIN356666 : Rea, Xouri, Akhtar: Males absent on the first (MOF): from flies to humans. in Oncogene 2007 (PubMed)
    Zeige alle 3 Referenzen für 356666

  2. Human Monoclonal KAT8 Primary Antibody für ICC, IHC - ABIN1724671 : Neal, Pannuti, Smith, Lucchesi: A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF. in Biochimica et biophysica acta 2000 (PubMed)
    Zeige alle 3 Referenzen für 1724671

  3. Human Monoclonal KAT8 Primary Antibody für IF, IHC (p) - ABIN1108370 : Sterner, Berger: Acetylation of histones and transcription-related factors. in Microbiology and molecular biology reviews : MMBR 2000 (PubMed)
    Zeige alle 2 Referenzen für 1108370

  4. Cow (Bovine) Polyclonal KAT8 Primary Antibody für WB - ABIN2783663 : Pfister, Rea, Taipale, Mendrzyk, Straub, Ittrich, Thuerigen, Sinn, Akhtar, Lichter: The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. in International journal of cancer. Journal international du cancer 2008 (PubMed)

Weitere Antikörper gegen K(lysine) Acetyltransferase 8 Interaktionspartner

Human K(lysine) Acetyltransferase 8 (KAT8) Interaktionspartner

  1. recent results indicate MOF is an upstream regulator of the ATM (ataxia-telangiectasia mutated (zeige ATM Antikörper)) protein, the loss of which is responsible for ataxia (zeige USP14 Antikörper) telangiectasia (AT). ATM (zeige ATM Antikörper) is a key regulatory kinase that interacts with and phosphorylates multiple substrates that influence critical, cell-cycle control and DNA damage repair pathways in addition to other pathways.

  2. Histone acetyltransferase (zeige HAT Antikörper) activity of MOF is required to sustain MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) leukemia and may be important for multiple AML (zeige RUNX1 Antikörper) subtypes.

  3. our findings reveal that TET1 (zeige TET1 Antikörper) forms a complex with hMOF to modulate its function and the level of H4K16Ac ultimately affect gene expression and DNA repair.

  4. these studies point to the critical and specific role of hMOF Lys (zeige LYZ Antikörper)-274 autoacetylation in hMOF stability and cognate substrate acetylation and argues that binding of Ac-CoA to hMOF likely drives Lys (zeige LYZ Antikörper)-274 autoacetylation for subsequent cognate substrate acetylation.

  5. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  6. MOF is highly enriched in induced pluripotent stem cells (iPSCs), and MOF expression is upregulated during the reprogramming process. The ectopic expression of MOF promotes reprogramming. MOF affects Wdr5 (zeige WDR5 Antikörper) and endogenous Oct4 (zeige POU5F1 Antikörper) expression.

  7. Along with the PHF20 (zeige PHF20 Antikörper)/MOF complex, G9a (zeige EHMT2 Antikörper) links the crosstalk between ERalpha (zeige ESR1 Antikörper) methylation and histone acetylation that governs the epigenetic regulation of hormonal gene expression.

  8. Data found downregulation of hMOF in gastric cancer cells and tissues. Declined hMOF expression, but not high level of HDAC4 (zeige HDAC4 Antikörper), may account for global histone H4K16ac suggesting that loss of hMOF expression may be involved in gastric cancer progression.

  9. EZH2 (enhancer of zeste homolog 2 (zeige EZH2 Antikörper)) was up-regulated in human oral tongue squamous cell carcinoma tissues and its level positively correlated with level of hMOF.

  10. Mutant MOF-T392A expression abrogates DSB repair in S/G2 (zeige STRN3 Antikörper) phase cells. MOF-T392A has delayed 53BP1 (zeige TP53BP1 Antikörper) dissociation and decreased DNA association.

Mouse (Murine) K(lysine) Acetyltransferase 8 (KAT8) Interaktionspartner

  1. MOF is a developmental-stage-specific chromatin regulator found to be essential for adult but not early fetal hematopoiesis.

  2. MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.

  3. STAT5B (zeige STAT5B Antikörper) and MOF work as negative regulators in adipogenesis.

  4. NSL and MSL HAT (zeige HAT Antikörper) complexes differentially regulate specific sets of expressed genes in mESCs and during differentiation

  5. cardiac-specific MOF overexpression protected mice from transverse aortic constriction-induced cardiac hypertrophy, with reduced radios of heart weight/body weight, decreased left ventricular wall thickness and increased fractional shortening.

  6. Mof plays a critical role in T-cell differentiation and that depletion of Mof in T cells reduces T-cell numbers and, by an undefined mechanism, induces genomic instability in B cells through bystander mechanism.

  7. Depletion of MOF in mouse embryonic stem cells causes a specific decrease in expression of a subset of X-linked genes.

  8. the histone acetyltransferase Mof plays an essential role in the maintenance of ESC self-renewal and pluripotency

  9. PHF20 (zeige PHF20 Antikörper) is not required for maintaining the global H4K16 acetylation levels or locus specific histone acetylation but instead works downstream in transcriptional regulation of MOF target genes

  10. Purkinje cells (PC)-specific deletion of the mouse males absent on the first (mMof) gene (Cre(-)), which encodes a protein that specifically acetylates histone H4 (zeige HIST1H4H Antikörper) at lysine 16 (H4K16ac) and influences ATM (zeige ATM Antikörper) function, is critical for PC longevity.

K(lysine) Acetyltransferase 8 (KAT8) Antigen-Profil

Protein Überblick

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit KAT8

  • MYST histone acetyltransferase 1 (myst1) Antikörper
  • K(lysine) acetyltransferase 8 (kat8) Antikörper
  • K(lysine) acetyltransferase 8 (MYST1) Antikörper
  • MYST histone acetyltransferase 1 (MYST1) Antikörper
  • MYST histone acetyltransferase 1 (LOC100341732) Antikörper
  • K (lysine) acetyltransferase 8 (Kat8) Antikörper
  • K(lysine) acetyltransferase 8 (KAT8) Antikörper
  • K(lysine) acetyltransferase 8 (Kat8) Antikörper
  • 2010203C02Rik Antikörper
  • 5830450F21Rik Antikörper
  • D7Ertd629e Antikörper
  • hMOF Antikörper
  • MOF Antikörper
  • MYST1 Antikörper
  • wu:fb22g02 Antikörper
  • wu:fj22d09 Antikörper
  • ZC2HC8 Antikörper
  • zgc:66387 Antikörper

Bezeichner auf Proteinebene für KAT8

MYST histone acetyltransferase 1 , histone acetyltransferase KAT8 , K(lysine) acetyltransferase 8 , probable histone acetyltransferase MYST1-like , MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 , MYST protein 1 , MYST-1 , lysine acetyltransferase 8 , probable histone acetyltransferase MYST1 , histone acetyltransferase MYST1 , ortholog of Drosophila males absent on the first (MOF) , histone acetyltransferase Myst1

GENE ID SPEZIES
548988 Xenopus (Silurana) tropicalis
100003790 Danio rerio
100019305 Monodelphis domestica
100064910 Equus caballus
100341732 Oryctolagus cuniculus
100387289 Callithrix jacchus
100435717 Pongo abelii
100522367 Sus scrofa
100593658 Nomascus leucogenys
310194 Rattus norvegicus
84148 Homo sapiens
67773 Mus musculus
479777 Canis lupus familiaris
100125883 Bos taurus
Ausgewählte Anbieter für anti-K(lysine) Acetyltransferase 8 (KAT8) Antikörper
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