MYST1 Antikörper (truncated)

Produktnummer ABIN2464086

Der Maus Monoklonal anti-MYST1 Antikörper (Klon 8C4C4) (ABIN2464086) detektiert spezifisch MYST1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MYST1 Antikörper (truncated) (ABIN2464086)

Target: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYST1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 8C4C4

Produktdetails anti-MYST1 Antikörper

Bindungsspezifität: truncated

Immunogen: Ni-NTA purified truncated recombinant MYST1-trx expressed in E. Coli strain BL21 (DE3).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: MYST1 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu MYST1

Target: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Andere Bezeichnung: MYST1

Hintergrund: MYST1 (MYST histone acetyltransferase 1,MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone.

Gen-ID: 84148

UniProt: Q9H7Z6