anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Antikörper

The protein encoded by HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). Zusätzlich bieten wir Ihnen HIF3A Kits (5) und HIF3A Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HIF3A 53417 Q0VBL6
HIF3A 64345 Q9JHS2
HIF3A 64344 Q9Y2N7
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Top anti-HIF3A Antikörper auf antikoerper-online.de

Showing 10 out of 98 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-HIF3A Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot using Affinity Purified anti-Hif3A antibody shows detection of a band ~72 kDa corresponding to mouse Hif3A (arrowhead).   Approximately 10 µg of a CoCl<sub>2</sub> treated 3T3 cell lysate (lane 1) and control 3T3 cell lysate (lane 2) were separated by 4-20% SDS-PAGE and transferred onto nitrocellulose.  Treatment of exponentially growing 3T3 cells with 130 µM CoCl<sub>2</sub> for 6 h at 37° C effectively mimics hypoxia.   After blocking the membrane was probed overnight at 4° C with the primary antibody diluted to 1:1,600.  The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-132-122) for 45 min at room temperature. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$379.00
Details
Human Kaninchen Unkonjugiert WB Detection of HIF-3 alpha in a reticulocyte lysate using ABIN151687. Western Blot: HIF-3 alpha Antibody [ABIN250675] - Analysis of HIF-3 alpha in Jurkat cell lysate. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: HIF-3 alpha Antibody [ABIN250965] - Hif3a expression in papillary renal cell carcinoma samples. Image from verified customer review. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Maus Kaninchen Unkonjugiert EIA, IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$411.18
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: HIF-3 alpha Antibody [NBP1-03155] - Staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Immunocytochemistry/Immunofluorescence: HIF-3 alpha Antibody [NBP1-03155] - (lane 1) 3T3 cell lysate and (lane 2) control 3T3 cell lysate. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Maus Unkonjugiert IHC, IHC (p), WB Immunohistochemistry: HIF-3 alpha Antibody (2D2) [NBP2-45735] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Western Blot: HIF-3 alpha Antibody (2D2) [NBP2-45735] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HIF3A. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$513.19
Details
Ratte Kaninchen Unkonjugiert WB Anti-HIF3 antibody, Western blotting WB: Rat Brain Tissue Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details

HIF3A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-HIF3A Antikörper

  1. Human Polyclonal HIF3A Primary Antibody für ICC, IF - ABIN250964 : Forooghian, Razavi, Timms: Hypoxia-inducible factor expression in human RPE cells. in The British journal of ophthalmology 2007 (PubMed)
    Show all 6 Pubmed References

  2. Mouse (Murine) Polyclonal HIF3A Primary Antibody für ELISA, WB - ABIN100475 : Takeda, Ho, Takeda, Duan, Nagy, Fong: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. in Molecular and cellular biology 2006 (PubMed)

  3. Human Polyclonal HIF3A Primary Antibody für WB - ABIN151687 : Jackson, Zhang, Hadley, Rabbani, Zhang, Marks, Vujaskovic: Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung. in Free radical biology & medicine 2012 (PubMed)

  4. Human Polyclonal HIF3A Primary Antibody für ICC, IF - ABIN315681 : Huang, Kapere Ochieng, Kempen, Munck, Swagemakers, van Ijcken, Grosveld, Tibboel, Rottier: Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development. in PLoS ONE 2013 (PubMed)

  5. Human Polyclonal HIF3A Primary Antibody für IHC, WB - ABIN2778530 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal HIF3A Primary Antibody für IHC, IHC (p) - ABIN4317485 : Liu, Fang, Song, Jiang, He, Liu: Expression of hypoxia-inducible factor 3α in hepatocellular carcinoma and its association with other hypoxia-inducible factors. in Experimental and therapeutic medicine 2016 (PubMed)

Weitere Antikörper gegen HIF3A Interaktionspartner

Cow (Bovine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Interaktionspartner

Zebrafish Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Interaktionspartner

Mouse (Murine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Interaktionspartner

  1. Report suggests that BV-2 microglial cells express HIF-3a under inflammatory conditions and that its activation differed from that of HIF-1a (zeige HIF1A Antikörper)

  2. mRNA of HIF-2alpha (zeige EPAS1 Antikörper) and Ets-1 (zeige ETS1 Antikörper) were significantly increased by HIF-3alpha ablation. Both factors activate the VE-cadherin (zeige CDH5 Antikörper) gene, the transcriptional repression of these factors by HIF-3alpha is important for silencing the irrelevant expression of the VE-cadherin (zeige CDH5 Antikörper) gene.

  3. our data indicated that Tnni2K175del mutation led to abnormally increased hif3a and decreased vegf in bone, which explain, at least in part, the small body size of Tnni2K175del mice

  4. Anoxia preconditioning increases anti-ischemic neuronal resistance which to a certain extent correlates with the changes of HIF-1alpha (zeige HIF1A Antikörper) and HIF-3alpha expression.

  5. alternative splicing and expression of IPAS is induced by hypoxia.

  6. By generating mice with a targeted disruption of the NEPAS/HIF-3alpha locus, it was found that homozygous mutant mice, NEPAS/HIF-3alpha(-/-), were viable but displayed enlargement of the right ventricle and impaired lung remodeling.

  7. Identity of third HIF alpha class member, HIF-3alpha. mRNA expression information by mouse MTN. Experimental proof of dimerization with ARNT/HIF-1beta (zeige ARNT Antikörper).

Human Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Interaktionspartner

  1. HIF3A methylation was found in the association between the HIF3A rs3826795 polymorphism and alanine aminotransferase (zeige ALT Antikörper) among obese children.

  2. TIMP2 (zeige TIMP2 Antikörper) suppression, in a hypoxic environment, was induced through a regulatory feedback circuit consisting of hypoxia-inducible factor (HIF) 1 alpha (zeige HIF1A Antikörper), microRNA-210 (miR (zeige MLXIP Antikörper)-210), and HIF-3alpha.

  3. Results were discordant with those expected if HIF3A methylation has a causal effect on body mass index (BMI) & provided more evidence for causality in the reverse direction (i.e., an effect of BMI on HIF3A methylation); results also show a long-lasting intergenerational influence of maternal BMI on offspring methylation at this locus, which may confound associations between own adiposity & HIF3A methylation.

  4. DNA methylation (zeige HELLS Antikörper) in HIF3A shares moderate correlation between adipose tissue and blood, and both are associated with BMI. In contrast, methylation in FASN (zeige FASN Antikörper) is poorly correlated across tissues, but the DNA methylation (zeige HELLS Antikörper) in adipose tissue but not blood is highly associated with BMI

  5. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (zeige HIF1A Antikörper) or Bcl-xL (zeige BCL2L1 Antikörper), binding proteins of IPAS in the nucleus and mitochondria, respectively.

  6. Results confirmed a positive association between BMI and HIF3A DNA promoter methylation in the blood. The tissue-specific results of HIF3A gene expression indicate that subcutaneous adipose tissue is the more functional tissue in which a low expression may adversely affect whole-body insulin (zeige INS Antikörper) sensitivity.

  7. Parkin (zeige PARK2 Antikörper) is downregulated under hypoxia and that it interferes with HIF expression based on cellular oxygen tension.

  8. This provides a compelling model for how hypoxia-induced miR (zeige MLXIP Antikörper)-429 regulates the switch between HIF-1 (zeige HIF1A Antikörper) adaptive responses to HIF-3 survival responses by rapidly decreasing HIF1A (zeige HIF1A Antikörper) levels while simultaneously slowing the progression of HIF3A expression until the miR (zeige MLXIP Antikörper)-429 levels drop below normoxic levels.

  9. The association between increased DNA methylation (zeige HELLS Antikörper) at HIF3A and increased adiposity is present in neonates.

  10. HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT

HIF3A Antigen-Profil

Protein Überblick

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit HIF3A

  • hypoxia inducible factor 3, alpha subunit (HIF3A) Antikörper
  • hypoxia-inducible factor 1, alpha subunit, like (hif1al) Antikörper
  • hypoxia inducible factor 3, alpha subunit (Hif3a) Antikörper
  • bHLHe17 Antikörper
  • HIF-3A Antikörper
  • HIF3A Antikörper
  • IPAS Antikörper
  • Mop7 Antikörper
  • NEPAS Antikörper
  • PASD7 Antikörper
  • zgc:63965 Antikörper

Bezeichner auf Proteinebene für HIF3A

hypoxia inducible factor 3, alpha subunit , Hif3a , Hif3a-like , hypoxia-inducible factor 3 alpha subunit , hypoxia-inducible factor 3-alpha , hypoxia-inducible factor-3 alpha , hypoxia-inducible factor 3-alpha-like , HIF-3-alpha , HIF3-alpha , HIF3-alpha-1 , basic-helix-loop-helix-PAS protein MOP7 , hypoxia inducible factor three alpha , inhibitory PAS domain protein , member of PAS protein 7 , neonatal and embryonic PAS , HIF-3 alpha , HIF3 alpha 1 , hypoxia inducible factor 3 alpha , hypoxia inducible factor 3a , hypoxia-inducible factor 3 alpha , PAS domain-containing protein 7 , class E basic helix-loop-helix protein 17

GENE ID SPEZIES
281815 Bos taurus
393376 Danio rerio
456149 Pan troglodytes
100135687 Ovis aries
100413902 Callithrix jacchus
100442498 Pongo abelii
100473029 Ailuropoda melanoleuca
100582446 Nomascus leucogenys
53417 Mus musculus
64345 Rattus norvegicus
64344 Homo sapiens
476429 Canis lupus familiaris
100621574 Sus scrofa
507699 Bos taurus
100071095 Equus caballus
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