Glycoprotein VI (Platelet) Proteine (GP6)

GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen GP6 Antikörper (77) und GP6 Kits (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GP6 243816 P0C191
GP6 51206 Q9HCN6
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Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
664,76 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
844,64 €
Details

GP6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)
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Human ,
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Weitere Proteine zu Glycoprotein VI (Platelet) (GP6) Interaktionspartnern

Mouse (Murine) Glycoprotein VI (Platelet) (GP6) Interaktionspartner

  1. These results reveal a novel and unexpected function of hepatic Fc-gamma-RIIB in the targeted downregulation of GPVI in vivo.

  2. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI.

  3. platelet GP6 and thromboxane A2 receptor (zeige TBXA2R Proteine) have a role in promoting inflammatory macrophage phenotype in skin inflammation

  4. Novel antithrombotic peptides derived from trowaglerix that acts through GPVI antagonism with greater safety-no severe bleeding.

  5. TULA-2 (zeige STS1 Proteine) Protein Phosphatase Suppresses Activation of Syk (zeige SYK Proteine) through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr (zeige TYR Proteine)(P)346, a Regulatory Site of Syk (zeige SYK Proteine).

  6. Inhibition of platelet activation by an anti-GPVI antibody significantly reduces infarct size.

  7. These results demonstrate that GPVI is a receptor for fibrin and provide evidence that this interaction contributes to thrombus growth and stability.

  8. data demonstrate that genetic deletion of GPVI receptor, FcRgamma (zeige FCER1G Proteine) chain, or the alpha2beta1 integrin changes the thrombotic potentials of these platelets to collagen dependent on the stimulus mechanism.

  9. data suggest a novel role for FAK (zeige PTK2 Proteine) in GPVI-dependent ROS (zeige ROS1 Proteine) formation and platelet activation and elucidate a proximal signaling role for FAK (zeige PTK2 Proteine) within the GPVI pathway.

  10. our results show that GPVI plays a dual role in inflammation by enhancing neutrophil-damaging activities while supporting the activation and hemostatic adhesion of single platelets to neutrophil-induced vascular breaches.

Human Glycoprotein VI (Platelet) (GP6) Interaktionspartner

  1. Novel antithrombotic peptides derived from trowaglerix that acts through GPVI antagonism with greater safety-no severe bleeding.

  2. results support the idea that genetic variability of GP6 regulatory regions can be associated with platelet hyperaggregability - a possible cause of miscarriage

  3. These results demonstrate that GP6 is a receptor for fibrin and provide evidence that this interaction contributes to thrombus growth and stability.

  4. data suggest a novel role for FAK (zeige PTK2 Proteine) in GPVI-dependent ROS (zeige ROS1 Proteine) formation and platelet activation and elucidate a proximal signaling role for FAK (zeige PTK2 Proteine) within the GPVI pathway.

  5. This study identifies GPVI as a platelet receptor for polymerized fibrin with 2 major functions: (1) amplification of thrombin (zeige F2 Proteine) generation and (2) recruitment of circulating platelets to clots.

  6. Glaucocalyxin A inhibits platelet activation and thrombus formation preferentially via GPVI signaling pathway.

  7. The plasma levels of sGPVI were the highest in patients with TMA without markedly reduced ADAMTS13 (zeige ADAMTS13 Proteine) and those were significantly reduced after plasma exchange.

  8. Results suggest that variants of GP6 SNPs, namely, rs1671153, rs1654410, rs1654419, and rs1613662, may be associated with risk of recurrent miscarriage.

  9. Lower platelet GPIV (zeige CD36 Proteine) levels are associated with no-reflow phenomenon in patients with acute myocardial infarction.

  10. Studies indicate that Megakaryocyte maturation is accompanied by up-regulation of glycoprotein VI and down-regulation of leukocyte-associated immunoglobulin-like receptor-1 (zeige LAIR1 Proteine).

GP6 Protein Überblick

Protein Überblick

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit GP6

  • glycoprotein VI (platelet) (GP6)
  • glycoprotein 6 (platelet) (Gp6)
  • 9830166G18Rik Protein
  • BDPLT11 Protein
  • Gm469 Protein
  • GPIV Protein
  • GPVI Protein

Bezeichner auf Proteinebene für GP6

glycoprotein VI (platelet) , glycoprotein 5 , platelet glycoprotein VI , glycoprotein 6 , platelet collagen receptor

GENE ID SPEZIES
456429 Pan troglodytes
484303 Canis lupus familiaris
243816 Mus musculus
51206 Homo sapiens
100141420 Sus scrofa
101123066 Ovis aries
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