anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Antikörper

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. Zusätzlich bieten wir Ihnen Glycoprotein Ib (Platelet), alpha Polypeptide Kits (15) und Glycoprotein Ib (Platelet), alpha Polypeptide Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GP1BA 691992  
GP1BA 14723 O35930
GP1BA 2811  
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Top anti-Glycoprotein Ib (Platelet), alpha Polypeptide Antikörper auf antikoerper-online.de

Showing 10 out of 209 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GP1BA Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB Host: Rabbit Target Name: GP1BA Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD42b expression in Hela (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Schaf Unkonjugiert CyTOF, FACS, WB Detection of Human CD42b/GPIb alpha in Human Whole Blood CD41+ Platelets by Flow Cytometry. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Maus Unkonjugiert FACS, Func, IHC (f) Surface staining of human platelets with anti-CD42b(HIP1) PE. 0.1 mg Anmelden zum Anzeigen 5 bis 7 Tage
$265.65
Details
Human Kaninchen Unkonjugiert IHC (p) Flow cytometric analysis of rabbit anti-CD42b (SP219) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue). 7 mL Anmelden zum Anzeigen 2 bis 3 Tage
$382.00
Details
Human Maus Unkonjugiert FACS Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b 0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$478.50
Details
Human Maus Biotin FACS Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b:BIOTIN 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$547.69
Details
Human Maus FITC FACS Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b:FITC 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$547.69
Details
Human Kaninchen Unkonjugiert IHC (p) 7 mL Anmelden zum Anzeigen 2 bis 3 Tage
$382.00
Details

GP1BA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus) ,


Mouse (Murine) ,


Human , , , ,
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Am meisten referenzierte anti-Glycoprotein Ib (Platelet), alpha Polypeptide Antikörper

  1. Human Monoclonal GP1BA Primary Antibody für ICC, FACS - ABIN2749168 : Welsh, Colace, Muthard, Stalker, Brass, Diamond: Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse. in Journal of thrombosis and haemostasis : JTH 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal GP1BA Primary Antibody für ICC, FACS - ABIN2749169 : Vettore, Scandellari, Moro, Lombardi, Scapin, Randi, Fabris et al.: Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome ... in Haematologica 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal GP1BA Primary Antibody für FACS, IF - ABIN1112144 : Williams, Jackson: Analysis of populations of macrophage-granulocyte progenitor cells stimulated by activities in mouse lung-conditioned medium. in Experimental hematology 1978 (PubMed)

  4. Dog (Canine) Polyclonal GP1BA Primary Antibody für WB - ABIN2784512 : Maguire, Thakkinstian, Sturm, Levi, Lincz, Parsons, Whyte, Attia: Polymorphisms in platelet glycoprotein 1balpha and factor VII and risk of ischemic stroke: a meta-analysis. in Stroke; a journal of cerebral circulation 2008 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal GP1BA Primary Antibody für FACS - ABIN2480381 : Sell, Purut, Silva, Jones: Recovery of myocardial function during coronary artery bypass grafting. Intraoperative assessment by pressure-volume loops. in The Journal of thoracic and cardiovascular surgery 1991 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal GP1BA Primary Antibody für FACS - ABIN2480379 : Burgess, Lopez, Berndt, Dawes, Chesterman, Chong: Quinine-dependent antibodies bind a restricted set of epitopes on the glycoprotein Ib-IX complex: characterization of the epitopes. in Blood 1998 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal GP1BA Primary Antibody für FACS, IP - ABIN2480375 : Burgess, Lopez, Gaudry, Chong: Rifampicin-dependent antibodies bind a similar or identical epitope to glycoprotein IX-specific quinine-dependent antibodies. in Blood 2000 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Glycoprotein Ib (Platelet), alpha Polypeptide Interaktionspartner

Cow (Bovine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. both the gpIb-VWF (zeige VWF Antikörper) interaction and the integrin alpha(2 (zeige ITGA2 Antikörper))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (zeige GSTA3 Antikörper))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (zeige VWF Antikörper) is bound

Mouse (Murine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. this study shows that atheroma formation is inhibited in GPIba-deficient mice on atherosclerosis-prone background

  2. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha-binding and heparin-binding site of thrombin (zeige F2 Antikörper)

  3. Thrombin (zeige F2 Antikörper) cleavage of platelet PAR4 (zeige F2RL3 Antikörper) promotes leukocyte recruitment to sites of vascular injury. This process is negatively regulated by GPIbalpha.

  4. GPIbalpha-mediated interactions between platelets and endothelial cells, as well as leukocytes, support innate immune cell recruitment and promote arteriogenesis-establishing platelets as critical players in this process.

  5. Atherosclerosis reduction in mice lacking GPIbalpha may not result from the defective GPIbalpha-ligand binding, but more likely is a consequence of functional defects of GPIbalpha-/- platelets and reduced blood platelet counts.

  6. Data suggest that targeting platelet receptor glycoprotein Ibalpha (GPIbalpha)-von Willebrand factor VWF (zeige VWF Antikörper)-A1 binding interface may offer a therapeutic approach to reducing platelet-driven thrombosis.

  7. Following endothelial damage, platelet cross-linking during closure of the vessel lumen is mediated by GPIbalpha-VWF (zeige VWF Antikörper) interactions.

  8. Platelet IKKbeta (zeige IKBKB Antikörper) deficiency increases the formation of injury-induced arterial neointimal tissue via delayed glycoprotein Ibalpha shedding.

  9. these data demonstrate that coordinated expression of GPIbalpha and filamin (zeige FLNA Antikörper) is required for efficient trafficking of either protein to the cell surface, and for production of normal-sized platelets.

  10. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbalpha and GPV (zeige GP5 Antikörper) for MP-dependent cleavage.

Human Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Interaktionspartner

  1. Loss of the platelet surface receptors GPIbalpha and GPVI (zeige GP6 Antikörper) in heart failure, CF-VAD (zeige KCTD1 Antikörper) and ECMO patients may contribute to ablated platelet adhesion/activation, and limit thrombus formation under high/pathologic shear conditions

  2. Very low birth weight preterm neonates have increased numbers of platelets interacting with von Willebrand Factor (zeige VWF Antikörper), and increased GPIbalpha expression on the platelet surface

  3. Data suggest that an aspartate at position 1261 is the most critical residue of VWF (zeige VWF Antikörper) N-terminal linker for inhibiting binding of VWF (zeige VWF Antikörper) A1 domain to GP1BA on platelets in a model simulating blood flow velocity; network of salt bridges between Asp1261 and rest of VWF (zeige VWF Antikörper) A1 domain lock N-terminal linker in place such that binding to GP1BA is reduced.

  4. Data show that von Willebrand factor (VWF (zeige VWF Antikörper)) is first converted from a compact to linear form by flow, and is subsequently activated to bind platelet glycoprotein Ib alpha polypeptide (zeige ITGAE Antikörper) (GPIbalpha) in a tension-dependent manner.

  5. The >30 nm macroglycopeptide separating the two domains of GPIbalpha transmits force on the VWF (zeige VWF Antikörper)-GPIbalpha bond (whose lifetime is prolonged by leucine-rich repeat domain unfolding) to the juxtamembrane mechanosensitive domain to enhance its unfolding, resulting in unfolding cooperativity at an optimal force.

  6. Meta-analysis found that glycoprotein Ia (zeige MMRN1 Antikörper) C807T T allele or the TT genotype, the Ser (zeige SIGLEC1 Antikörper)-allele of HPA-3 and B allele of glycoprotein Ibalpha variable number tandem repeat polymorphisms were associated with increased risk for ischemic stroke.

  7. Our results suggest that the -5CC genotype in Kozak sequence of GPIb-alpha may be associated with a higher risk of developing arterial ischemia of lower limbs in type 2 diabetes mellitus patients.

  8. Specific inhibition of GPIbalpha shedding in the stored platelets improves post-transfusion platelet recovery and hemostatic function, providing clear evidence for GPIbalpha shedding as a cause of platelet clearance.

  9. miR (zeige MLXIP Antikörper)-10a and miR10b regulate the expression of human platelet GP1BA and GP1bb (zeige GP1BB Antikörper) for normal megakaryopoiesis.

  10. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF (zeige VWF Antikörper)) or type I collagen under shear stresses.

Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Antigen-Profil

Protein Überblick

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Genbezeichner und Symbole assoziert mit GP1BA

  • glycoprotein Ib platelet alpha subunit (Gp1ba) Antikörper
  • glycoprotein Ib (platelet), alpha polypeptide (GP1BA) Antikörper
  • glycoprotein Ib platelet alpha subunit (GP1BA) Antikörper
  • glycoprotein 1b, alpha polypeptide (Gp1ba) Antikörper
  • BDPLT1 Antikörper
  • BDPLT3 Antikörper
  • BSS Antikörper
  • CD42B Antikörper
  • CD42b-alpha Antikörper
  • DBPLT3 Antikörper
  • GP1B Antikörper
  • GP1BA Antikörper
  • GPIbA Antikörper
  • GPIbalpha Antikörper
  • VWDP Antikörper

Bezeichner auf Proteinebene für GP1BA

glycoprotein 1b, alpha polypeptide , platelet glycoprotein Ib alpha chain , glycoprotein Ib (platelet), alpha polypeptide , platelet glycoprotein Ib alpha polypeptide , GP-Ib alpha , glycoprotein Ibalpha , antigen CD42b-alpha , platelet membrane glycoprotein 1b-alpha subunit , GPIb-alpha , GPIbA

GENE ID SPEZIES
691992 Rattus norvegicus
420059 Gallus gallus
468166 Pan troglodytes
504977 Bos taurus
14723 Mus musculus
2811 Homo sapiens
403638 Canis lupus familiaris
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