anti-Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Antikörper

GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. Zusätzlich bieten wir Ihnen GAD Kits (34) und GAD Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GAD1 14415 P48318
GAD1 24379 P18088
GAD1 2571 Q99259
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Top anti-GAD Antikörper auf antikoerper-online.de

Showing 10 out of 186 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB GAD1 Antibody (C-term) (ABIN655175) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the GAD1 antibody detected the GAD1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN334405 (1µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Ratte Maus Unkonjugiert ICC, IP Immunolabeling of cultured hippocampus neurons (dilution 1 : 500). 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
385,00 €
Details
Maus Ziege Unkonjugiert ELISA, WB Western Blot: GAD1/GAD67 Antibody [NBP2-27555] - NBP2-27555 (1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Ziege Unkonjugiert ELISA, ICC, IF, WB Western Blot: GAD1/GAD67 Antibody [NBP1-06989] - Staining of Human Brain (Cerebellum) 35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Huhn Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunohistochemistry: GAD1/GAD67 Antibody [NBP1-02161] - Immunohistochemical staining of mouse hippocampus (2% paraformaldehyde-fixation followed by embedding in paraffin blocks, following standard methods) using NBP1-02161 at a dilution of 1:1000. Red cells represent GAD-expressing inhibitory satellite cells found within the molecular layer of the dentate gyrus. 0.5 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-GAD1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Placenta WB Suggested Anti-GAD1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human Placenta 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB Anti- GAD67 Picoband antibody, Western blotting All lanes: Anti GAD67  at 0.5ug/ml WB: Recombinant Human GAD67 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details

GAD1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GAD Antikörper

  1. Human Polyclonal GAD Primary Antibody für WB - ABIN655175 : Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? in Pharmacogenomics 2010 (PubMed)

  2. Human Polyclonal GAD Primary Antibody für ICC, IF - ABIN314830 : Valladolid-Acebes, Merino, Principato, Fole, Barbas, Lorenzo, García, Del Olmo, Ruiz-Gayo, Cano: High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission. in American journal of physiology. Endocrinology and metabolism 2012 (PubMed)

  3. Mouse (Murine) Polyclonal GAD Primary Antibody für ELISA, WB - ABIN4313131 : Wang, Wang, Ferris, Salit, Strulovici-Barel, Hackett, Crystal: Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium. in Respiratory research 2010 (PubMed)

  4. Human Polyclonal GAD Primary Antibody für ELISA, ICC - ABIN451637 : Mouton-Liger, Sahún, Collin, Lopes Pereira, Masini, Thomas, Paly, Luilier, Même, Jouhault, Bennaï, Beloeil, Bizot, Hérault, Dierssen, Créau: Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome. in Neurobiology of disease 2014 (PubMed)

  5. Rat (Rattus) Monoclonal GAD Primary Antibody für ICC, IP - ABIN1742414 : Mikhaylova, Karpova, Bär, Bethge, YuanXiang, Chen, Zuschratter, Behnisch, Kreutz: Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain. in Brain structure & function 2014 (PubMed)

  6. Human Polyclonal GAD Primary Antibody für ELISA, WB - ABIN334405 : Huang, Akbarian: GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia. in PLoS ONE 2007 (PubMed)

Weitere Antikörper gegen GAD Interaktionspartner

Mouse (Murine) Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Interaktionspartner

  1. GABA is the major inhibitory neurotransmitter in the brain. We show that Dlx1/Dlx2 homeobox (zeige PRRX1 Antikörper) genes regulate GABA synthesis during forebrain development through direct activation of glutamic acid decarboxylase enzyme isoforms that convert glutamate (zeige GRIN1 Antikörper) to GABA.

  2. The UCHL1 (zeige UCHL1 Antikörper) may play a role in myogenesis by promoting myoblast proliferation and inhibiting differentiation.

  3. our study provides novel insights into the mechanisms of UCH-L1 (zeige UCHL1 Antikörper)-mediated neurobiological functions and suggests that ubiquitination is an important regulatory signal for TrkB (zeige NTRK2 Antikörper)

  4. These findings reveal that Th and Gad1 share a transcription regulatory mechanism that facilitates odorant-dependent regulation of dopamine and GABA expression levels.

  5. Study describes in detail a population of choline acetyltransferase immunoreactive /glutamate decarboxylase 67 neurons predominantly ventral to the central canal of the cervical, thoracic and lumbar spinal cord of adult and juvenile mice. These cells potentially correspond to a sub-population of the cholinergic central canal cluster cells which may play a unique role in controlling spinal cord circuitry.

  6. This study demonstrated that Alterations in hypoglossal motor neurons due to GAD67 deficiency in mice.

  7. Treadmill running prevented partial sciatic nerve ligation-induced reductions in GAD65 (zeige GAD2 Antikörper)/67 production, and, thus, GABA levels may be retained in interneurons and neuropils in the superficial dorsal horn.

  8. Effects of Ubiquitin C-Terminal Hydrolase (zeige UCHL1 Antikörper) L1 (UCH-L1 (zeige UCHL1 Antikörper)) inhibition on sperm incorporation and cortical tension in mouse eggs.

  9. Gad1 knockdown mice have pronounced sensorimotor gating deficits, increased novelty-seeking and reduced fear extinction

  10. The neuronal marker UCH-L1 (zeige UCHL1 Antikörper) is induced in, and specifically augments the oncogene (zeige RAB1A Antikörper)-induced transformation of, germinal center B cells.

Arabidopsis thaliana Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Interaktionspartner

  1. mutations in the two lobes affect GAD1 activation in similar ways and only intact AtCaM1 can fully activate GAD1. Taken together, our data provide new insights into the CaM (zeige CALM Antikörper) lobes role in interactions between CaM (zeige CALM Antikörper) and plant GAD.

  2. Insertion mutants of GAD1 revealed that GABA levels in roots were drastically reduced compared with those in the wild type.

  3. Calmodulin (zeige CALM Antikörper) activates Gad1 in a unique way by relieving two C-terminal autoinhibition domains of adjacent active sites, forming a 393 kDa Gad1-calmodulin (zeige CALM Antikörper) complex with an unusual 1:3 stoichiometry.

Human Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Interaktionspartner

  1. Results show how epigenetic changes in GAD1 expression alter local glutamate (zeige GRIN1 Antikörper) metabolism in the brain metastatic microenvironment, contributing to a metabolic adaption that facilitates metastasis outgrowth in that setting.

  2. We investigate the possible influence of GAD1 SNPs rs3749034 and rs11542313 on ADHD susceptibility. The C allele of rs11542313 was significantly overtransmitted from parents to ADHD probands. Hyperactive/impulsive score was higher in rs3749034G allele and rs11542313C allele carriers. GAD1 haplotypes were associated with higher hyperactive/impulsive scores in ADHD youths. GAD1 gene is associated with ADHD susceptibility.

  3. GAD1 is reactivated by DNA methylation (zeige HELLS Antikörper), which provided a model for DNA methylation (zeige HELLS Antikörper) and the active orchestration of oncogenic gene expression by CTCF (zeige CTCF Antikörper) in cancer cells.

  4. There was no difference in GAD25 and GAD67 gene expression level, and GAD25/GAD67 ratio between patients with first episode psychosis and healthy controls

  5. Genetic variability in GAD1 and GAD2 (zeige GAD2 Antikörper) contributes to the risk of methamphetamine dependence in the Thai population.

  6. Reduced GAD67 expression in PV neurons is not an upstream cause of the lower levels of GABA-associated transcripts, or of the characteristic behaviors, in schizophrenia.

  7. Glutamic acid decarboxylase 67 (GAD67) is one of the isoforms that catalyze GABA synthesis. Here, we used recombinant herpes simplex virus (HSV-1) vectors that encode gad1 gene to evaluate the therapeutic potential of GAD67 in peripheral HIV gp120 (zeige ITIH4 Antikörper)-induced neuropathic pain

  8. This study showed that in female groups, the expression of GABRA5 (zeige GABRA5 Antikörper) was generally higher in schizophrenia cases compared to the control.

  9. GAD autoantibodies were associated with risk of developing type 1 diabetes.

  10. Conversion of GAD autoantibody is associated with patients with presumed type 2 diabetes.

Cow (Bovine) Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Interaktionspartner

  1. These results suggest that the GAD1 gene is a strong candidate gene that affects growth traits in cattle.

Zebrafish Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) Interaktionspartner

  1. relative expression domains of the dlx and gad1 genes in the zebrafish telencephalon and diencephalon

  2. High levels of GAD67 mRNA were observed in the intermediate and ventral parts of the medial pallium

  3. the distribution of GAD67-expressing cells highly resembles the distribution of gamma-aminobutyric acid (GABA)/GAD67-expressing cells found in the early zebrafish (teleost) forebrain, suggesting a prosomeric fate map of GABAergic cell populations

GAD (GAD1) Antigen-Profil

Protein Überblick

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Genbezeichner und Symbole assoziert mit GAD1

  • glutamate decarboxylase 1 (brain, 67kDa), gene 1 (gad1.1) Antikörper
  • glutamate decarboxylase 1 (brain, 67kDa) (GAD1) Antikörper
  • glutamate decarboxylase 1 (AOR_1_946174) Antikörper
  • glutamate decarboxylase 1 (AOR_1_562034) Antikörper
  • glutamate decarboxylase 1 (Gad1) Antikörper
  • glutamate decarboxylase 1 (GAD) Antikörper
  • glutamate decarboxylase 1b (gad1b) Antikörper
  • ubiquitin carboxy-terminal hydrolase L1 (Uchl1) Antikörper
  • AO090005000539 Antikörper
  • AO090103000342 Antikörper
  • AW822034 Antikörper
  • C88048 Antikörper
  • CPSQ1 Antikörper
  • EP10 Antikörper
  • gad Antikörper
  • Gad-1 Antikörper
  • GAD-67 Antikörper
  • GAD1 Antikörper
  • gad1-A Antikörper
  • GAD2 Antikörper
  • GAD25 Antikörper
  • GAD44 Antikörper
  • Gad67 Antikörper
  • glutamate decarboxylase Antikörper
  • GLUTAMATE DECARBOXYLASE 1 Antikörper
  • MKP11.30 Antikörper
  • MKP11_30 Antikörper
  • PGP9.5 Antikörper
  • PGP 9.5 Antikörper
  • R75593 Antikörper
  • SCP Antikörper
  • UCH-L1 Antikörper
  • UCHL-1 Antikörper

Bezeichner auf Proteinebene für GAD1

glutamate decarboxylase 1 , glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) , glutamic acid decarboxylase 65-like protein , 67 kDa glutamic acid decarboxylase , GAD-67 , GLUTAMATE DECARBOXYLASE, 67 KD ISOFORM (GAD-67) (67 KD GLUTAMIC ACID DECARBOXYLASE) , glutamate decarboxylase 67 kDa isoform , glutamic acid decarboxylase 1 , Glutamate decarboxylase 1 (brain) , glutamate decarboxylase 1 variant GAD67NT , glutamic acid decarboxylase , glutamate decarboxylase 67 , glutamate decarboxylase, 67 kDa isoform , gracile axonal dystrophy , neuron cytoplasmic protein 9.5 , protein gene product 9.5 , ubiquitin carboxyl-terminal hydrolase isozyme L1 , ubiquitin thioesterase L1

GENE ID SPEZIES
378551 Xenopus laevis
778442 Taeniopygia guttata
778447 Taeniopygia guttata
5989537 Aspergillus oryzae RIB40
5999037 Aspergillus oryzae RIB40
100173252 Pongo abelii
14415 Mus musculus
24379 Rattus norvegicus
831599 Arabidopsis thaliana
2571 Homo sapiens
493699 Felis catus
478794 Canis lupus familiaris
396928 Sus scrofa
517552 Bos taurus
395743 Gallus gallus
468557 Pan troglodytes
378441 Danio rerio
22223 Mus musculus
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