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C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM, May 2008].. Zusätzlich bieten wir Ihnen Gastrin Antikörper (132) und Gastrin Kits (101) und viele weitere Produktgruppen zu diesem Protein an.
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Results demonstrate that gastrin increases the expression of the autophagy markers MAP1LC3B (zeige MAP1LC3B Proteine)-II and SQSTM1 (zeige SQSTM1 Proteine) in gastric adenocarcinoma cells. Gastrin induces autophagy via activation of the STK11 (zeige STK11 Proteine)-PRKAA2 (zeige PRKAA2 Proteine)-ULK1 (zeige ULK1 Proteine) and that this signaling pathway is involved in increased migration and cell survival.
PTHLH is a gastrin-regulated growth factor that might contribute to gastric epithelial cell homeostasis.
Gastrin is expressed in both in (zeige INS Proteine)sulin(+) and somatostatin(+) cells in adults with type 2 diabetes.
Gastrin induced ABCG2 expression by activating NF-kappaB (zeige NFKB1 Proteine) and thereby modulated the side population proportion, tumor cell metastatic potential and invasion activity in pancreatic cancer.
CTGF (zeige CTGF Proteine) is overexpressed in gastric cancer and adjacent tissue compared to normal gastric tissue. Gastrin induces expression of CTGF (zeige CTGF Proteine) in gastric epithelial cells.
Data show that 6 of 20 primary pancreatic neuroendocrine tumors (PNETs) had positive staining for multiple hormones gastrin, insulin (zeige INS Proteine), glucagon (zeige GCG Proteine), and somatostatin (zeige SST Proteine), and positive expression of 1 or more hormones was found in 9 of 12 nonfunctioning PNETs [NF-PNETs]) patients.
Gastrin role in gastric epithelial homeostasis and gastric carcinogenesis
Results suggest a role for Toll-like receptor 4 (zeige TLR4 Proteine) in gastric acid regulation and that the Toll-like receptor 4 (TLR4 (zeige TLR4 Proteine)) +896 and +1196 wild type homozygozity increases peptic ulcer risk via gastrin secretion.
Serum pepsinogens I (PGI (zeige BGN Proteine)) and II (PGII (zeige DCN Proteine)), gastrin 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA (zeige S100A8 Proteine)) antigen among 309 consecutive patients, were measured.[Pepsinogen I, Gastrin 17]
treatment with gastrin, a CCK2R (zeige CCKBR Proteine) agonist, stimulated the secretion of GLP-1 (zeige GCG Proteine), and that this effect was likely due to increased expression of proglucagon (zeige GCG Proteine) and PCSK1 (zeige PCSK1 Proteine) (also known as prohormone convertase 3 (PC3 (zeige PCSK1 Proteine) gene)).
Gastrin induces nuclear export and proteasome degradation of menin in duodenal glial cells.
Renal-selective silencing of Gast by the renal subcapsular injection of Gast siRNA in BALB/c mice decreases renal dopamine production and increases blood pressure.
Gastrin is expressed in insulin (zeige INS Proteine) secreting cells of adult diabetic mice.
Ihh (zeige IHH Proteine) signaling mediates gastrin-induced proliferation of epithelial cells in stomachs of adult mice.
mouse corneal afferent sensory neurons expressed CCK and GAST, and the CCK1R receptors.
Data indicate that epithelial Gli2 expression was sufficient to stimulate Il-1beta (zeige IL1B Proteine) expression, repress Gast gene expression and increase proliferation, leading to antral hyperplasia.
Initiation of antral gastric cancer is associated with progressive epigenetic silencing of TFF1 (zeige TFF1 Proteine), which can be suppressed by the hormone gastrin.
Regulation of mouse gastrin gene in vivo. Mechanisms involved in transcriptional control of the gastrin gene.
Serum gastrin decreased significantly in the cholesterol gallstone groups compared to the control group.
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17.