anti-Formin Binding Protein 1-Like (FNBP1L) Antikörper

The protein encoded by FNBP1L binds to both CDC42 and N-WASP. Zusätzlich bieten wir Ihnen FNBP1L Proteine (4) und FNBP1L Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FNBP1L 54874 Q5T0N5
FNBP1L 214459 Q8K012
FNBP1L 310839 Q2HWF0
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Top anti-FNBP1L Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FNBP1L Antibody  in mouse lung tissue lysates (35ug/lane). This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB FNBP1L Antibody (Center)  western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: FNBP1L Antibody [NBP1-76846] - Human Brain cells. Western Blot: FNBP1L Antibody [NBP1-76846] - Human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with FNBP1L antibody at 0.5 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FNBP1L Antibody [NBP1-76845] - Human brain tissue with FNBP1L antibody at 2.5 ug/ml. Immunocytochemistry/Immunofluorescence: FNBP1L Antibody [NBP1-76845] - Immunofluorescence of TOCA-1 in Human Brain cells with TOCA-1 antibody at 20 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human Kidney (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with FNBP1L antibody ABIN461907 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: FNBP1L Antibody [NBP1-80569] - Human lung carcinoma. Antibody used at a dilution of 1:1,000 (1ug/mg). Western Blot: FNBP1L Antibody [NBP1-80569] - Whole cell lysate from Jurkat (15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg) and HeLa (H; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-Toca-1 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. Toca-1 was also immunoprecipitated by rabbit anti-Toca-1 antibody NBP1-80563 which recognizes an upstream epitope. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details

FNBP1L Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen FNBP1L Interaktionspartner

Human Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

  2. Loss of p53 tumor suppressor (zeige TP53 Antikörper) function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.

  3. GWAS results show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts; FNBP1L was also significantly associated with childhood intelligence

  4. findings suggest that Toca-1 functions at an early step in the dissemination of metastatic breast tumor cells; taken together, results identify Toca-1 as a proinvasive protein in breast adenocarcinoma

  5. Toca-1 knockdown cells also display a significant defect in EGF (zeige EGF Antikörper)-induced motility and invasiveness.

  6. Cdc42 may influence endocytic membrane trafficking by regulating the formation and activity of the Toca-1/N-WASP complex.

  7. Toca-1 promotes actin nucleation by activating the N-WASP-WIP/CR16 complex, the predominant form of N-WASP in cells.

  8. a vesicle trafficking regulator Toca-1 regulates different aspects of neuronal morphology from N-WASP

  9. We show that actin tail initiation by S. flexneri requires Toca-1 for the conversion of N-WASP from a closed inactive conformation to an open active one.

  10. the Toca-1-N-WASP complex can link filopodial formation to endocytosis

Mouse (Murine) Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. Toca-1(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP.

Xenopus laevis Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

  1. This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

FNBP1L Antigen-Profil

Protein Überblick

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit FNBP1L

  • formin binding protein 1 like (FNBP1L) Antikörper
  • formin binding protein 1-like (Fnbp1l) Antikörper
  • formin binding protein 1-like (fnbp1l) Antikörper
  • formin binding protein 1 like (fnbp1l) Antikörper
  • formin binding protein 1 like L homeolog (fnbp1l.L) Antikörper
  • formin binding protein 1 like S homeolog (fnbp1l.S) Antikörper
  • 2610318I01Rik Antikörper
  • AW548221 Antikörper
  • C1orf39 Antikörper
  • fnbp1l Antikörper
  • MGC132162 Antikörper
  • RGD1305386 Antikörper
  • toca-1 Antikörper
  • toca1 Antikörper
  • zgc:100923 Antikörper

Bezeichner auf Proteinebene für FNBP1L

formin-binding protein 1-like , toca-1 , transducer of Cdc42-dependent actin assembly 1 , transducer of Cdc42-dependent actin assembly protein 1 , Cdc42 effector , formin binding protein 1-like , transducer of Cdc42-dependent actin assembly-1 , Transducer of Cdc42-dependent actin assembly protein 1

GENE ID SPEZIES
54874 Homo sapiens
214459 Mus musculus
310839 Rattus norvegicus
424495 Gallus gallus
445240 Danio rerio
448740 Xenopus (Silurana) tropicalis
469385 Pan troglodytes
479942 Canis lupus familiaris
616665 Bos taurus
713578 Macaca mulatta
735241 Xenopus laevis
100032840 Monodelphis domestica
100059052 Equus caballus
100077332 Ornithorhynchus anatinus
100157977 Sus scrofa
100338578 Oryctolagus cuniculus
100405015 Callithrix jacchus
100448000 Pongo abelii
100476131 Ailuropoda melanoleuca
100559983 Anolis carolinensis
446802 Xenopus laevis
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