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FNBP1L Antikörper (N-Term)

FNBP1L Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501004
  • Target Alle FNBP1L Antikörper anzeigen
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 46
    • 20
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FNBP1L Antikörper ist unkonjugiert
    Applikation
    • 21
    • 18
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects FNBP1L at N-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TOCA-1 antibody was raised against a 15 amino acid peptide near the amino terminus of the human TOCA-1.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 0.5 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Andere Bezeichnung
    FNBP1L (FNBP1L Produkte)
    Synonyme
    C1orf39 antikoerper, TOCA1 antikoerper, 2610318I01Rik antikoerper, AW548221 antikoerper, RGD1305386 antikoerper, Toca-1 antikoerper, zgc:100923 antikoerper, toca1 antikoerper, toca-1 antikoerper, MGC132162 antikoerper, fnbp1l antikoerper, formin binding protein 1 like antikoerper, formin binding protein 1-like antikoerper, formin binding protein 1 like L homeolog antikoerper, formin binding protein 1 like S homeolog antikoerper, FNBP1L antikoerper, Fnbp1l antikoerper, fnbp1l antikoerper, fnbp1l.L antikoerper, fnbp1l.S antikoerper
    Hintergrund
    Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells, its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.Synonyms: C1orf39, Formin-binding protein 1-like, TOCA1, Transducer of Cdc42-dependent actin assembly protein 1
    Gen-ID
    54874
    NCBI Accession
    NP_001020119
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