anti-Fc Fragment of IgA, Receptor For (FCAR) Antikörper

FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Zusätzlich bieten wir Ihnen Fc Fragment of IgA, Receptor For Kits (27) und Fc Fragment of IgA, Receptor For Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FCAR 2204 P24071
FCAR    
FCAR    
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Top anti-Fc Fragment of IgA, Receptor For Antikörper auf antikoerper-online.de

Showing 10 out of 192 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Antibody (Center) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus PE FACS ABIN118856 (Mouse anti human CD89: RPE) staining of peripheral blood granulocytes. 100 Tests Anmelden zum Anzeigen 6 bis 8 Tage
$456.50
Details
Human Maus Unkonjugiert EIA, FACS, IP, WB   25 μg Anmelden zum Anzeigen 6 bis 8 Tage
$176.00
Details
Human Maus Unkonjugiert BP, FACS   0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$304.00
Details
Human Maus Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$304.00
Details
Human Kaninchen Unkonjugiert WB Anti-CD89 antibody, Western blotting Lane 1: A549 Cell Lysate Lane 2: U87 Cell Lysate Lane 3: RAJI Cell Lysate Lane 4: JURKAT Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Maus Unkonjugiert FACS, IP, ELISA, WB 0.1 mg Anmelden zum Anzeigen 3 bis 4 Tage
$280.82
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Antibody (Center) (ABIN656839). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert FACS, IF   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$445.50
Details

FCAR Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) ,

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Mouse (Murine)


Am meisten referenzierte anti-Fc Fragment of IgA, Receptor For Antikörper

  1. Human Monoclonal FCAR Primary Antibody für FACS - ABIN2472756 : Depierre, Dallner: Structural aspects of the membrane of the endoplasmic reticulum. in Biochimica et biophysica acta 1976 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal FCAR Primary Antibody für FACS, IP - ABIN2472754 : Zhang, Bi, Oldroyd, Lachmann: Neutrophil lactoferrin release induced by IgA immune complexes differed from that induced by cross-linking of fcalpha receptors (FcalphaR) with a monoclonal antibody, MIP8a. in Clinical and experimental immunology 2000 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal FCAR Primary Antibody für Func, FACS - ABIN2472758 : Duc, Johansen, Corthésy: Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal FCAR Primary Antibody für FACS - ABIN2472759 : Lu, Marjon, Marnell, Wang, Mold, Du Clos, Sun: Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal FCAR Primary Antibody für IHC (fro), FACS - ABIN2689431 : Monteiro, Cooper, Kubagawa: Molecular heterogeneity of Fc alpha receptors detected by receptor-specific monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)

Weitere Antikörper gegen Fc Fragment of IgA, Receptor For Interaktionspartner

Cow (Bovine) Fc Fragment of IgA, Receptor For (FCAR) Interaktionspartner

  1. have mapped the IgA binding site of bovine IgA Fc receptor and show that, in common with CD89, Tyr-35 in the B-C loop is essential for IgA binding

Pig (Porcine) Fc Fragment of IgA, Receptor For (FCAR) Interaktionspartner

Human Fc Fragment of IgA, Receptor For (FCAR) Interaktionspartner

  1. In transgenic mice, IgAN pathogenesis involves impaired clearance of abnormal IgA via CD89, primarily by the Kupffer cells. Conditional IgAN progression in CD89 transgenic mice thus reveals important aspects of IgAN pathogenesis.

  2. a novel Fcar splice variant termed variant APD isolated from a healthy volunteer that lacks only the IgA-binding EC1 domain, is reported.

  3. Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus.

  4. this study examined the expression of IL-4 mRNA, IFN-c mRNA and FcaRI mRNA in tonsillar mononuclear cells of IgA nephropathy9(IgAN) patients and non-IgAN patients.

  5. FCAR polymorphism is not associated with high susceptibility to IGA nephropathy in caucasians.

  6. Abnormally glycosylated IgA1 and soluble CD89-IgA and IgA-IgG complexes, features of primary IgA nephropathy, are also present in alcoholic cirrhosis.

  7. Genetic variation at the promoter region of IgA receptor is associated with IgA nephropathy.

  8. These results suggest a role of anti-FcaRI Fab (zeige FANCB Antikörper) as a negative regulator in controlling the magnitude of the innate immune response

  9. Glycosylation of the CH2 (zeige Acyp1 Antikörper)/CH3 (zeige SOX3 Antikörper) interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR (zeige PIGR Antikörper), essential to the biosynthesis and transport of SIgA.

  10. There is an association between the levels of sCD89-IgA complexes in serum and the severity of IgA nephropathy, and a possible genetic component in regulating the production or expression of sCD89.

Fc Fragment of IgA, Receptor For (FCAR) Antigen-Profil

Protein Überblick

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit FCAR

  • Fc fragment of IgA receptor (FCAR) Antikörper
  • Fc fragment of IgA, receptor for (FCAR) Antikörper
  • CD89 Antikörper

Bezeichner auf Proteinebene für FCAR

IgA Fc receptor , immunoglobulin A Fc receptor , immunoglobulin alpha Fc receptor , Fc fragment of IgA, receptor for, isoform 7 , Fc alpha receptor

GENE ID SPEZIES
503555 Bos taurus
664734 Macaca mulatta
100050205 Equus caballus
100137567 Papio anubis
100144539 Sus scrofa
2204 Homo sapiens
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