anti-FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) Antikörper

FXYD1 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. Zusätzlich bieten wir Ihnen FXYD1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FXYD1 5348 O00168
FXYD1 56188 Q9Z239
FXYD1 58971  
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Top anti-FXYD1 Antikörper auf antikoerper-online.de

Showing 10 out of 96 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- FXYZ1 Picoband antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue Anti- FXYZ1 Picoband antibody, IHC(P) IHC(P): Human Prostatic Cancer Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Maus Kaninchen Unkonjugiert WB PLM Antibody (E1) (ABIN1882173) western blot analysis in mouse heart,skeletal muscle and rat heart,skeletal muscle tissue lysates (35 µg/lane). This demonstrates the PLM antibody detected the PLM protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Maus Kaninchen Unkonjugiert DB, WB Dot blot analysis of anti-Phospho-mPLM-pS88.repeat Phospho-specific Pab (ABIN389683) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. The anti-Mouse Phospho-PLM-pS88 Pab (ABIN389683) is used for detection in mouse heart tissue lysate. Mouse Phospho-PLM-pS88 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Maus Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Maus Maus Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Maus Maus Unkonjugiert WB Western blot analysis of anti-PLM Mab (ABIN387765) in 293 cells transfected with a plasmid encoding PLM. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
436,70 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
436,70 €
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FXYD1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FXYD1 Antikörper

  1. Mouse (Murine) Polyclonal FXYD1 Primary Antibody für WB - ABIN1882173 : Nakajima-Takenaka, Zhang, Obata, Tohne, Matsuyoshi, Nagai, Nishiyama, Takaki: Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics. in American journal of physiology. Heart and circulatory physiology 2009 (PubMed)

Weitere Antikörper gegen FXYD1 Interaktionspartner

Human FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) Interaktionspartner

  1. Study demonstrated that the expression of FXYD1, FXYD3 (zeige FXYD3 Antikörper) and FXYD5 (zeige FXYD5 Antikörper) is elevated in the lungs of Acute respiratory distress syndrome patients

  2. a period of high-intensity training with reduced training volume increases expression and phosphorylation levels of FXYD1, which may affect Na(+)/K(+) pump activity and muscle K(+) homeostasis during intense exercise.

  3. Stopped-flow experiments using the dye RH421 show that FXYD1 slows the conformational transition E2(2K)ATP --> E1(3Na)ATP but does not affect 3NaE1P --> E2P3Na.

  4. the evolutionary conservation of G-quadruplex forming sequences with the confirmation of G-quadruplex formation in vitro by two FXYD1 homologues

  5. Phospholemman is the target of a variety of post-translational modifications and these can dynamically alter the activity of the Na pump. [Review]

  6. PLM regulates important ion transporters in the heart and offers a tempting target for development of drugs to treat heart failure.

  7. Intracellular trafficking of FXYD1 (phospholemman) and FXYD7 (zeige FXYD7 Antikörper) proteins in Xenopus oocytes and mammalian cells.

  8. the severity of the spinal cord lesion is an important factor controlling the expression of Na(+)-K(+)-ATPase (zeige ATP1A1 Antikörper) and its regulatory protein PLM

  9. in left ventricular myocardium from patients with heart failure, PLM Ser (zeige SIGLEC1 Antikörper)-68 phosphorylation was approximately 50% lower than in nonfailing controls

  10. Exercise induces FXYD1 phosphorylation at multiple sites in human muscle; in mice, contraction-induced changes in FXYD1 phosphorylation are fiber-type specific and dependent on protein kinase (zeige CDK7 Antikörper) Calpha (zeige PRKACA Antikörper) activity.

Cow (Bovine) FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) Interaktionspartner

  1. the evolutionary conservation of G-quadruplex forming sequences with the confirmation of G-quadruplex formation in vitro by two FXYD1 homologues

Pig (Porcine) FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) Interaktionspartner

  1. S68 phospholemman phosphorylation may be involved in cAMP-dependent regulation of smooth muscle force.

  2. Phospholemman does not participate in forskolin-induced swine carotid artery relaxation.

Mouse (Murine) FXYD Domain Containing Ion Transport Regulator 1 (FXYD1) Interaktionspartner

  1. Both the extracellular PFXYD motif and the transmembrane domain of PLM but not the cytoplasmic tail were necessary for regulation of peak L-type Ca(2 (zeige CA2 Antikörper)+) current amplitude.

  2. Decreased phosphorylation of PLM reduces Na/K pump activity and exacerbates Na overload, contractile dysfunction, and adverse remodelling following aortic constriction in mice.

  3. Nitric oxide activates Na/K-ATPase (zeige ATP1A1 Antikörper) via phospholemman phosphorylation.

  4. The results of this study indicated that reducing FXYD1 levels improves a specific cognitive impairment in MECP2-deficient mice.

  5. Alterations in PLM expression and phosphorylation are important adaptations post-myocardial infarction.

  6. Exercise induces FXYD1 phosphorylation at multiple sites in human muscle; in mice, contraction-induced changes in FXYD1 phosphorylation are fiber-type specific and dependent on protein kinase (zeige CDK7 Antikörper) Calpha (zeige PRKACA Antikörper) activity.

  7. The results of this study showed the involvement of epigenetic mechanisms in the manifestation of brain region-specific differences in Fxyd1 expression.

  8. Under catecholamine stress when [Na+]i is high, phospholemman minimizes [Na+]i overload by relieving its inhibition of Na+-K+-ATPase (zeige ATP1A1 Antikörper) and preserves inotropy by simultaneously inhibiting Na+/Ca2+ exchanger (zeige SLC8A1 Antikörper).

  9. Under stressful conditions in which [Na(+)](i) was high, beta-adrenergic agonist-mediated phosphorylation of phospholemman resulted in time-dependent reduction in inotropy due to relief of inhibition of Na(+)-K(+)-ATPase (zeige ATP1A1 Antikörper).

  10. a primary effect of phospholemman is to modulate the Na-K-ATPase (zeige ATP1A1 Antikörper) and that its reduced activity initiates compensatory responses in heart hypertrophy

FXYD1 Antigen-Profil

Protein Überblick

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.

Genbezeichner und Symbole assoziert mit FXYD1

  • FXYD domain containing ion transport regulator 1 (FXYD1) Antikörper
  • FXYD domain-containing ion transport regulator 1 (Fxyd1) Antikörper
  • 0610012C17Rik Antikörper
  • 1110006M24Rik Antikörper
  • Plm Antikörper
  • Pml Antikörper

Bezeichner auf Proteinebene für FXYD1

FXYD domain containing ion transport regulator 1 , phospholemman , FXYD domain containing ion transport regulator 1 (phospholemman) , FXYD domain-containing ion transport regulator 1

GENE ID SPEZIES
747770 Pan troglodytes
5348 Homo sapiens
476487 Canis lupus familiaris
616139 Bos taurus
100127481 Sus scrofa
56188 Mus musculus
58971 Rattus norvegicus
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