anti-F-Box Protein 32 (FBXO32) Antikörper

FBXO32 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Zusätzlich bieten wir Ihnen FBXO32 Kits (29) und FBXO32 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FBXO32 114907 Q969P5
FBXO32 67731 Q9CPU7
FBXO32 171043 Q91Z62
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Top anti-FBXO32 Antikörper auf antikoerper-online.de

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FBXO32 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-FBXO32 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Fbxo32 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Mouse Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN570946 (1 µg/mL) staining of Human Skeletal Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat uterus labeled with Anti MAFbx/Fbx32 Polyclonal Antibody, Unconjugated (bs2591R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Maus Kaninchen Unkonjugiert WB Western Blot: Fbx32 Antibody [NBP1-79517] - Mouse heart lysate, 1 ug/ml 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$375.38
Details

FBXO32 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FBXO32 Antikörper

  1. Human Polyclonal FBXO32 Primary Antibody für IF (p), IHC (p) - ABIN747698 : Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016 (PubMed)

  2. Human Polyclonal FBXO32 Primary Antibody für ELISA, WB - ABIN451805 : Hanai, Cao, Tanksale, Imamura, Koshimizu, Zhao, Kishi, Yamashita, Phillips, Sukhatme, Lecker: The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. in The Journal of clinical investigation 2007 (PubMed)

Weitere Antikörper gegen FBXO32 Interaktionspartner

Zebrafish F-Box Protein 32 (FBXO32) Interaktionspartner

  1. Atrogin-1 inactivation leads to progressive impairment of heart and skeletal muscle function and structure. Autophagy is severely impaired in Atrogin-1-deficient zebrafish embryos.

Rainbow Trout (Oncorhynchus mykiss) F-Box Protein 32 (FBXO32) Interaktionspartner

  1. Results suggest that the up-regulation of FBXO32 is associated with skeletal and smooth muscle atrophy that occurs during fasting.

Human F-Box Protein 32 (FBXO32) Interaktionspartner

  1. Low FBXO32 expression is associated with breast cancer tumorigenesis.

  2. the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system

  3. These results have revealed the roles for atrogin-1 in the regulation of smooth muscle contractility through enhancement of myocardin (zeige MYOCD Antikörper) ubiquitylation/degradation and its transcriptional activity.

  4. Our results indicate that abnormal SCF (zeige KITLG Antikörper) activity with subsequent impairment of the autophagic flux due to a novel FBXO32 mutation is implicated in the pathogenesis of Dilated cardiomyopathy .

  5. Our data suggest that FBXO32 is a candidate gene for recessive familial dilated cardiomyopathy. Acting as a cardiac ubiquitin ligase, mutated FBXO32 could perturb the degradation of target proteins in the ubiquitin proteasome system.

  6. Vitamin D3 might have an inhibitory effect on the expression of MAFbx and MuRF1 (zeige TRIM63 Antikörper) in skeletal muscle.

  7. Atrogin-1 expression tended to be increased in the skeletal muscle of patients with malignant disease even before c (zeige TNF Antikörper)ancer related cachexia weight loss.

  8. Expression of USP19 (zeige USP19 Antikörper) correlates with that of MuRF1 (zeige TRIM63 Antikörper) and MAFbx/atrogin-1 in skeletal muscles

  9. FBXO32 targets Lys (zeige LYZ Antikörper)-326 of c-Myc (zeige MYC Antikörper) to form polyubiquitin (zeige UBB Antikörper) chains, resulting in inhibition of cell proliferation.

  10. In conclusion, atrogin-1, MuRF1 (zeige TRIM63 Antikörper), FOXO1 (zeige FOXO1 Antikörper)/3A, and eIF3 (zeige EIF3A Antikörper)-f mRNA, and protein levels, are differentially regulated by exercise contraction mode but not WPH supplementation combined with hypertrophy-inducing training.

Pig (Porcine) F-Box Protein 32 (FBXO32) Interaktionspartner

  1. this study shows that aspartate suppresses lipopolysaccharide-induced MAFbx expression in skeletal muscle via activation of Akt (zeige AKT1 Antikörper) signaling, and inhibition of AMPKa and FOXO1 (zeige FOXO1 Antikörper) signaling

  2. Porcine congenital splayleg (PCS) is a condition characterized by extensive fibre atrophy and raised fibre density. The combined differential expression of MAFbx and P311 (zeige C5orf13 Antikörper) is of potential in the diagnosis of subclinical PCS.

Cow (Bovine) F-Box Protein 32 (FBXO32) Interaktionspartner

  1. A study on the variability of bovine FBXO32 gene that is predictive of genetic potential for body length phenotype.

Mouse (Murine) F-Box Protein 32 (FBXO32) Interaktionspartner

  1. Valproic acid attenuated muscle wasting and myotube atrophy and reduced C/EBPbeta (zeige CEBPB Antikörper) binding to atrogin1 promoter locus in the myotubes.

  2. These results have revealed the roles for atrogin-1 in the regulation of smooth muscle contractility through enhancement of myocardin (zeige MYOCD Antikörper) ubiquitylation/degradation and its transcriptional activity.

  3. educed PABPN1 (zeige PABPN1 Antikörper) levels caused a consistent decline in distal PAS (zeige PASK Antikörper) utilization in the 3'-UTR (zeige UTS2R Antikörper) of a subset of OPMD-dysregulated genes. This alternative PAS (zeige PASK Antikörper) utilization led to up-regulation of Atrogin-1, a key muscle atrophy regulator, but down regulation of proteasomal genes. Additionally reduced PABPN1 (zeige PABPN1 Antikörper) levels caused a reduction in proteasomal activity, and transition in MyHC (zeige MYH13 Antikörper) isotope expression pattern in myofibers.

  4. Iron-induced skeletal muscle atrophy is suggested to involve the E3 ubiquitin ligase (zeige MUL1 Antikörper) mediated by the reduction of Akt (zeige AKT1 Antikörper)-FOXO3a (zeige FOXO3 Antikörper) signaling by oxidative stress.

  5. MAFbx mRNA expression was decreased in old mice relative to adult mice, whereas MuRF1 (zeige TRIM63 Antikörper) mRNA expression was less affected by ageing

  6. Suggest role for atrogin-1 up-regulation in simvastatin-induced heart mitochondria dysfunction.

  7. Atrogin1 was upregulated in cancer cachexia mice. Atrogin1 knockdown protected skeletal muscle cells from TNF-alpha (zeige TNF Antikörper) induced atrophy.

  8. Expression of USP19 (zeige USP19 Antikörper) correlates with that of MuRF1 (zeige TRIM63 Antikörper) and MAFbx/atrogin-1 in skeletal muscles

  9. MAFbx not only regulates protein degradation, but also reduces protein synthesis, exerting a dual role in regulating cardiac mass and preventing from cardiac hypertrophy.

  10. mechanical vibration strongly down-regulates atrophy genes myostatin (zeige MSTN Antikörper) and atrogin-1 both in vivo and in vitro.

FBXO32 Antigen-Profil

Protein Überblick

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit FBXO32

  • F-box protein 32 (fbxo32) Antikörper
  • F-box protein 32 (FBXO32) Antikörper
  • F-box protein 32 (Fbxo32) Antikörper
  • 4833442G10Rik Antikörper
  • AI430017 Antikörper
  • Atrogin1 Antikörper
  • Fbx32 Antikörper
  • Gm20361 Antikörper
  • MAFbx Antikörper
  • MGC56479 Antikörper
  • zgc:56479 Antikörper

Bezeichner auf Proteinebene für FBXO32

F-box only protein 32 , atrogin-1 , F-box protein 32 , F-box only protein 32-like , atrogin 1 , muscle atrophy F-box protein , atrophy gene 1

GENE ID SPEZIES
393891 Danio rerio
420343 Gallus gallus
464371 Pan troglodytes
475091 Canis lupus familiaris
704804 Macaca mulatta
100026040 Monodelphis domestica
100057506 Equus caballus
100142676 Ovis aries
100356177 Oryctolagus cuniculus
100387690 Callithrix jacchus
100462679 Salmo salar
100499214 Oncorhynchus mykiss
100580109 Nomascus leucogenys
114907 Homo sapiens
733657 Sus scrofa
513776 Bos taurus
67731 Mus musculus
171043 Rattus norvegicus
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