FBXO32 Antikörper

Produktnummer ABIN7267090

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch FBXO32 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FBXO32 Antikörper (ABIN7267090)

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FBXO32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FBXO32 Antikörper

Verwendungszweck: Fbx32/FBOX32 Rabbit mAb

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Fbx32/FBOX32

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000, IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Andere Bezeichnung: FBXO32

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],Fbx32, MAFbx,Cardiovascular,Cell Biology & Developmental Biology,Heart,Heart_Hypertrophy,Mesenchymal Stem Cells,Stem Cells,Ubiquitin,FBXO32

Molekulargewicht: 42kDa

Gen-ID: 114907

UniProt: Q969P5