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The protein encoded by DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Zusätzlich bieten wir Ihnen Desmocollin 1 Kits (12) und Desmocollin 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 66 products:
Human Polyclonal Desmocollin 1 Primary Antibody für IHC, IHC (p) - ABIN4304997
Paavilainen, Edvinsson, Asplund, Hober, Kampf, Pontén, Wester: The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2010
Show all 2 Pubmed References
Human Monoclonal Desmocollin 1 Primary Antibody für CyTOF, FACS - ABIN4899241
Ikawa-Yoshida, Matsumoto, Okano, Aoyagi, Matsubara, Furuyama, Nakatsu, Tsuzuki, Onimaru, Ohkusa, Nomura, Maehara: BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality. in Scientific reports 2016
DSC1 (zeige RCAN1 Antikörper) expression is significantly downregulated in human masticatory mucosa during wound healing
Increased expression of DSC1 (zeige RCAN1 Antikörper) can promote the occurrence of head and neck squamous cell carcinoma (HNSCC) and is associated with tumor. The increased expression of DSC1 (zeige RCAN1 Antikörper) also indicates a poor prognosis of the patients with HNSCC.
Low expression of DSC 1 (zeige RCAN1 Antikörper), 2, and 3 was observed in 55, 54, and 79 % of liver metastases.
High expression of desmocollin 1 (DSC1) was observed in 41.6%, DSC2 (zeige DSC2 Antikörper) in 58.0%, DSC3 (zeige DSC2 Antikörper) in 61.4%, E-cadherin (zeige CDH1 Antikörper) in 71.4%, CDX2 (zeige CDX2 Antikörper) in 58.0%, PITX1 (zeige PITX1 Antikörper) in 55.0%, CDK4 (zeige CDK4 Antikörper) in 0.2%, TLE1 (zeige TLE1 Antikörper) in 1.3%, Factor H (zeige CFH Antikörper) in 42.5%, and MDM2 (zeige MDM2 Antikörper) in 0.2% of colorectal carcinomas.
The ultrastructural modifications of desmosomes during terminal differentiation of hair follicles are paralleled by the modulation of the synthesis of desmocollin 1.
in majority of patients with Netherton syndrome (zeige SPINK5 Antikörper), Dsg1 (zeige DSG1 Antikörper) & Dsc1 (zeige RCAN1 Antikörper) were reduced in living layers of epidermis; SCTE (zeige KLK5 Antikörper)-like & SCCE (zeige KLK7 Antikörper)-like activities were increased, suggesting these proteases participate in premature degradation of corneodesmosomal cadherins
Increased Dsc1 (zeige RCAN1 Antikörper) protein is associated with colorectal cancer
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
, cadherin family member 1
, desmosomal glycoprotein 2/3