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The protein encoded by DMC1 is essential for meiotic homologous recombination. Zusätzlich bieten wir Ihnen DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Proteine (4) und DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal DMC1 Primary Antibody für EIA, FACS - ABIN951926
Volodin, Bocharova, Smirnova, Camerini-Otero: Reversibility, equilibration, and fidelity of strand exchange reaction between short oligonucleotides promoted by RecA protein from escherichia coli and human Rad51 and Dmc1 proteins. in The Journal of biological chemistry 2009
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Human Monoclonal DMC1 Primary Antibody für IP, WB - ABIN151318
Masson, Davies, Hajibagheri, Van Dyck, Benson, Stasiak, Stasiak, West: The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. in The EMBO journal 2000
The DMC1 was highly variable from cell to cell, whereas foci of the crossover marker MLH1 (zeige MLH1 Antikörper) showed little variability.
RAD51AP1 (zeige RAD51AP1 Antikörper) foci colocalize with a subset of DMC1 foci in spermatocytes.
p53 (zeige TP53 Antikörper) might be involved in homologous recombination and/or checkpoint function by directly binding to DMC1 protein to repress genomic instability in meiotic germ cells
TBPIP/HOP2 (zeige PSMC3IP Antikörper) directly binds to DNA and functions as an activator for DMC1 during the homologous pairing step in meiosis
data reveal an interplay among Hop2 (zeige PSMC3IP Antikörper), Mnd1 (zeige MND1 Antikörper) and Rad51 (zeige RAD51 Antikörper) and Dmc1 in the formation of the first recombination intermediates during meiosis
Mei1 (zeige MEI1 Antikörper) can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis
Dmc1(Mei11) exposes a sex difference in recombination in that a significant portion of female oocytes can compensate for DMC1 deficiency to undergo crossing-over and complete gametogenesis.
Data indicate that ahomologous pairing by DMC1 protein or RAD51 (zeige RAD51 Antikörper) recombinase (zeige RAG1 Antikörper) in chromatin containing nucleosome-depleted double-stranded DNA (dsDNA) regions.
BRCA2 (zeige BRCA2 Antikörper) protein stimulates DMC1-mediated DNA strand exchange between RPA (zeige RPA1 Antikörper)-ssDNA complexes and duplex DNA, thus identifying BRCA2 (zeige BRCA2 Antikörper) as a mediator of DMC1 recombination function.
Dmc1 can reject divergent DNA sequences while bypassing a few mismatches in the DNA sequence.
In contrast to RAD51 (zeige RAD51 Antikörper), stabilization of the presynaptic filament via ATP hydrolysis attenuation is insufficient for enhancement of the DMC1-catalyzed recombination reaction.
truncated DMC1 octamers further stack with alternate polarity into a filament
results suggested mutations in the coding sequence of DMC1 are not associated with premature ovarian failure in Chinese women
The results suggested that PSF (zeige IGFBP7 Antikörper) may function as an activator for the meiosis-specific recombinase (zeige RAG1 Antikörper) DMC1.
RAD51-associated protein 1 (RAD51AP1 (zeige RAD51AP1 Antikörper)) interacts with the meiotic recombinase (zeige RAG1 Antikörper) DMC1 through a conserved motif.
D-loops in a human DMC1-driven reaction are substantially more resistant to dissociation by branch-migration proteins such as RAD54 (zeige ATRX Antikörper) than those formed by RAD51 (zeige RAD51 Antikörper).
The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined.
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
, RecA homolog Dmc1
, disrupted meiotic cDNA 1
, meiotic recombination protein DMC1/LIM15 homolog
, meiotic recombination protein DMC1/LIM15 homolog-like
, meiotic recombination protein dmc1/lim15-like protein
, disrupted meiotic cDNA 1 homolog
, DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
, disrupted meiotic cDNA1, yeast, homolog of