anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Antikörper

CYP46A1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Proteine (4) und Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYP46A1 10858 Q9Y6A2
CYP46A1 13116 Q9WVK8
CYP46A1 362782  
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Antikörper auf antikoerper-online.de

Showing 10 out of 85 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CYP46A1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Detection of Cyp46 in human brain lysates using ABIN152907. Detection of Cyp46 in human cortex using ABIN152907. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Maus Kaninchen Unkonjugiert WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
600,64 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse brain, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with CYP46 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged CYP46A1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Maus Unkonjugiert ELISA, IHC, WB Immunohistochemistry: CYP46A1 Antibody (N8-P6E4-H8) [NBP2-50194] - Shows strong cytoplasmic staining in metastatic colorectal cancer (A) and primary colorectal (B) compared to normal colon mucosa (C). Western Blot: CYP46A1 Antibody (N8-P6E4-H8) [NBP2-50194] - The left hand lane contains control cell lysate while the right hand lane contains lysate prepared from cells over-expressing the protein. ~15 micrograms of protein were loaded per well. No bands were detected with the negative control lysate, while a band migrating at the expected molecular weight was observed in the over-expression lysate. 0.1 mL Anmelden zum Anzeigen 7 bis 10 Tage
242,00 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: CYP46A1 Antibody [NBP2-16066] - Sample (30 ug of whole cell lysate) A: MCF-7 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details

CYP46A1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , ,


, , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , , , ,

Am meisten referenzierte anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Antikörper

  1. Human Polyclonal CYP46A1 Primary Antibody für ELISA, WB - ABIN2472977 : Mesa-Ramos, García Criado, Mellado Rider, Mesa-Ramos, Alfaro Rodríguez, Carpintero Benítez: Modifications of the normal sonographic image in gluteal fibrosis. in Acta orthopaedica Belgica 1992 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CYP46A1 Primary Antibody für ICC, IF - ABIN152907 : Brown, Theisler, Silberman, Magnuson, Gottardi-Littell, Lee, Yager, Crowley, Sambamurti, Rahman, Reiss, Eckman, Wolozin: Differential expression of cholesterol hydroxylases in Alzheimer's disease. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Interaktionspartner

Human Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Interaktionspartner

  1. Data suggest that CYP46A1, the enzyme responsible for the majority of cholesterol elimination from the brain, exhibits activation by neurotransmitters, L-glutamate (zeige GRIN1 Antikörper), L-aspartate, gamma-aminobutyric acid, and acetylcholine; L-glutamate (zeige GRIN1 Antikörper)-induced CYP46A1 activation may be of physiological relevance.

  2. CYP46A1 rs4900442 genetic polymorphism was associated with increased risk of Alzheimer disease in the Chinese population, but no evidences were detected in Caucasian population.

  3. Findings of this study suggest that CYP46A1 gene and PPARgamma2 (zeige PPARG Antikörper) gene polymorphisms can be a predictive marker for early identification of population at risk of primary open angle glaucoma (POAG).

  4. hippocampal CYP46A1 protein and 24S-hydroxycholesterol levels were reduced in a mouse model of Alzheimer's Disease-like Tau neuropathology

  5. under conditions of membrane cholesterol reduction by increased CYP46A1 expression, neurons increase isoprenoid synthesis and sGTPase prenylation. This leads to a reduction in liver X receptor activity

  6. Human CYP46A1 oxidizes 7-dehydrocholesterol to 24-hydroxy-7-dehydrocholesterol and 25-hydroxy-7-dehydrocholesterol.

  7. While there were no differences in cognitive performance between participants with and those without metabolic syndrome, ApoE (zeige APOE Antikörper) and CYP46 genotypes did correlate with mental manipulation scores.

  8. results of meta-analysis suggested that CYP46A1 rs754203 is a minor risk factor for Alzheimer's disease

  9. An meta-analysis has successfully proved that CC genotype of the CYP46A1 T/C polymorphism could increase the risk of Alzheimer's disease.

  10. A meta-analysis indicates that the CYP46 gene SNP rs754203 is not significantly associated with sporadic Alzheimer's disease susceptibility in Chinese Han populations.

Cow (Bovine) Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Interaktionspartner

  1. EFV enhanced CYP46A1 activity and cerebral cholesterol turnover in animals with no effect on the levels of brain cholesterol.

  2. analysis of binding of the cyano- and fluoro-containing drug bicalutamide to cytochrome P450 46A1

Mouse (Murine) Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Interaktionspartner

  1. Increased expression of CYP46A1 in the striatum decreased neuronal atrophy in a Huntington's disease model.

  2. under conditions of membrane cholesterol reduction by increased CYP46A1 expression, neurons increase isoprenoid synthesis and sGTPase prenylation. This leads to a reduction in liver X receptor activity

  3. EFV enhanced CYP46A1 activity and cerebral cholesterol turnover in animals with no effect on the levels of brain cholesterol.

  4. the CYP46 gene locus may predispose to Alzheimer's disease by increasing the 24S-hydroxycholesterol/cholesterol ratio in the brain.

  5. The expression of CYP46A1, as well as other cytochrome P450s involved in cholesterol homeostasis, are potently regulated by histone acetylation status.

Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Antigen-Profil

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Genbezeichner und Symbole assoziert mit CYP46A1

  • cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1) Antikörper
  • cytochrome P450, family 46, subfamily A, polypeptide 1 (cyp46a1) Antikörper
  • cytochrome P450, family 46 (cyp46a1) Antikörper
  • cytochrome P450 46A1 (PTRG_08343) Antikörper
  • cytochrome P450 46A1 (PTRG_09667) Antikörper
  • cholesterol 24-hydroxylase (Sgly_1093) Antikörper
  • cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1) Antikörper
  • CP46 Antikörper
  • Cyp46 Antikörper
  • CYP46A1 Antikörper
  • MGC147389 Antikörper
  • zgc:109896 Antikörper

Bezeichner auf Proteinebene für CYP46A1

cholesterol 24-hydroxylase , cytochrome P450, family 46, subfamily A, polypeptide 1 , cytochrome P450, family 46 , cytochrome P450 46A1 , CH24H , cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) , cholesterol-24S-hydroxylase , cholestrol 24-hydroxylase , cytochrome P450, 46 (cholesterol 24-hydroxylase) , cytochrome P450, 46a1 (cholesterol 24-hydroxylase)

GENE ID SPEZIES
423450 Gallus gallus
453154 Pan troglodytes
553543 Danio rerio
780005 Xenopus (Silurana) tropicalis
100145328 Xenopus (Silurana) tropicalis
6346625 Pyrenophora tritici-repentis Pt-1C-BFP
6347960 Pyrenophora tritici-repentis Pt-1C-BFP
10248273 Syntrophobotulus glycolicus DSM 8271
10858 Homo sapiens
379470 Xenopus laevis
506438 Bos taurus
13116 Mus musculus
362782 Rattus norvegicus
Ausgewählte Anbieter für anti-Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Antikörper
Haben Sie etwas anderes gesucht?