anti-Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Antikörper

CYP27A1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen CYP27A1 Kits (11) und CYP27A1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYP27A1 1593 Q02318
CYP27A1 104086 Q9DBG1
CYP27A1 301517 P17178
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Top anti-CYP27A1 Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CYP27A1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of Cytochrome P450 27A1 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytochrome P450 27A1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using Cytochrome P450 27A1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver tissue labeled with Anti-CYP27A1 Polyclonal Antibody, Unconjugated (ABIN708911) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image CYP27A1 antibody detects CYP27A1 protein at cytoplasm in human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. CYP27A1 antibody , diluted at 1:500. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: CYP27A1 Antibody [NBP2-16063] - Immunohistochemical analysis of paraffin-embedded hela xenograft, using antibody at 1:500 dilution. Western Blot: CYP27A1 Antibody [NBP2-16063] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details

CYP27A1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CYP27A1 Antikörper

  1. Human Polyclonal CYP27A1 Primary Antibody für WB - ABIN2784620 : Szlago, Gallus, Schenone, Patiño, Sfaelo, Rufa, Da Pozzo, Cardaioli, Dotti, Federico: The first cerebrotendinous xanthomatosis family from Argentina: a new mutation in CYP27A1 gene. in Neurology 2008 (PubMed)

  2. Human Polyclonal CYP27A1 Primary Antibody für EIA, IF - ABIN272272 : Duan, Fu, Wang, Ni, Zhao: Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens. in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2014 (PubMed)

Weitere Antikörper gegen CYP27A1 Interaktionspartner

Human Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. we demonstrated the rare missense variant of CYP27A1 is associated with atopic dermatitis with elevated levels of total serum IgE.

  2. The 32 kb deleted region harbors the CYP2A7 (zeige CYP2A7 Antikörper) gene and was enriched with enhancer, repressor and insulator sites. The wildtype allele was lost in the polyps of the proband

  3. CYP27A1 is a critical cellular cholesterol sensor in prostate cells and that dysregulation of the CYP27A1/27-hydroxycholesterol (27HC) axis contributes significantly to prostate cancer pathogenesis.

  4. CYP27A1 catalyzes hydroxylation of beta-sitosterol and ergosterol

  5. CYP46A1 (zeige CYP46A1 Antikörper) is involved in cholestanol removal from the brain and that several factors contribute to the preferential increase in cholestanol in the cerebellum arising from CYP27A1 deficiency.

  6. A significant decrease in the expression level of CYP27A1 in female patients could indicate their greater vulnerability to multiple sclerosis than the male patients.

  7. CYP27A1 belongs to the mitochondrial CYPs and plays a crucial role in the cholesterol homeostasis.

  8. Analysis of ~60,000 human exomes points to underdiagnosis of cerebrotendinous xanthomatosis due to CYP27A1 mutations.

  9. marinobufagenin is derived from bile acids and its biosynthesis is initiated by CYP27A1 enzyme

  10. The 25-hydroxylases CYP2R1 (zeige CYP2R1 Antikörper) and CYP27A1 catalyze vitamin D to its circulating form 25-hydroxyvitamin D.

Mouse (Murine) Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. CYP46A1 (zeige CYP46A1 Antikörper) is involved in cholestanol removal from the brain and that several factors contribute to the preferential increase in cholestanol in the cerebellum arising from CYP27A1 deficiency.

  2. The cholesterol diet reduced the levels of the "memory protein" Arc (Activity Regulated Cytoskeleton associated protein (zeige Arc Antikörper)) in the hippocampus of the wildtype mice but not in the hippocampus of the Cyp27-/- mice.

  3. overexpression of Cyp27a1 in KCs reduces hepatic inflammation independently of 27HC levels in plasma and liver, further pointing towards KCs as specific target for improving the therapy of NASH (zeige SAMSN1 Antikörper).

  4. Data indicate that inhibition of CYP27A1 activity or knockdown and deletion of the Cyp27a1 gene induced adipocyte differentiation.

  5. The expression of CYP27A1 modulates the concentrations of active glucocorticoids in both humans and mice and in vitro.

  6. Loss of CYP27A1 led to dysregulation of retinal cholesterol homeostasis, including unexpected upregulation of retinal cholesterol biosynthesis. Cyp27a1-/- mice developed retinal lesions with cholesterol deposition beneath the retinal pigment epithelium.

  7. CYP27(-/-) mice exhibited enhanced CCl(4 (zeige CCL4 Antikörper))-induce liver injury, and defective liver regeneration and prolonged steatosis after 70% partial hepatectomy.

  8. Results are consistent with a concentration-dependent flux of 7alpha-hydroxy-4-cholesten-3-one across the blood-brain barrier in cyp27a1(-/-) mice and subsequent formation of cholestanol.

  9. In CYP27A1 ko mice, urinary progesterone concentrations were decreased, 20alpha-DH-progesterone increased, and the progesterone-to-20alpha-DH-progesterone ratio decreased threefold

  10. Hepatic neutral cytosolic cholesteryl ester hydrolase decreased mRNAs for cholesterol 7alpha-hydroxylase (zeige CYP7A1 Antikörper), sterol 27-hydroxylase, and HMG-CoA reductase (zeige HMGCR Antikörper) on day 7 after transfection, coinciding with peak hepatic free cholesterol concentrations

Cow (Bovine) Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. isoLG adduction impairs enzyme activity, and support our hypothesis that isoLG modification in the retina is detrimental to CYP27A1 enzyme activity, potentially disrupting cholesterol homeostasis.

  2. Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 (zeige POR Antikörper) CYP27A1 and CYP11A1 (zeige CYP11A1 Antikörper).

  3. Sterol 27-hydroxylase cytochrome P450 27A1 (CYP27A1) is involved in elimination of 7-ketocholesterol from the retinal pigment epithelium.

CYP27A1 Antigen-Profil

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Genbezeichner und Symbole assoziert mit CYP27A1

  • cytochrome P450 family 27 subfamily A member 1 (CYP27A1) Antikörper
  • cytochrome P450, family 27, subfamily a, polypeptide 1 (Cyp27a1) Antikörper
  • cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1) Antikörper
  • sterol 26-hydroxylase, mitochondrial (CYP27A1) Antikörper
  • vitamin D3 25-Hydroxylase (CYP2D25) Antikörper
  • 1300013A03Rik Antikörper
  • CP27 Antikörper
  • CTX Antikörper
  • Cyp27 Antikörper
  • CYPIID25 Antikörper
  • P450C27 Antikörper

Bezeichner auf Proteinebene für CYP27A1

5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase , 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase , 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase , cholestanetriol 26-monooxygenase , cytochrome P-450C27/25 , cytochrome P450 27 , cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 , sterol 26-hydroxylase, mitochondrial , sterol 27-hydroxylase , vitamin D(3) 25-hydroxylase , cholesterol 27 hydroxylase , cytochrome P450, 27 , cytochrome P450, 27a1 , cytochrome P-450c27/25 , cytochrome P-450 , cytochrome P450 2D25

GENE ID SPEZIES
1593 Homo sapiens
104086 Mus musculus
610489 Canis lupus familiaris
100126282 Sus scrofa
511960 Bos taurus
301517 Rattus norvegicus
100348736 Oryctolagus cuniculus
397687 Sus scrofa
Ausgewählte Anbieter für anti-CYP27A1 (CYP27A1) Antikörper
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