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CLDN7 encodes a member of the claudin family. Zusätzlich bieten wir Ihnen Claudin 7 Kits (28) und Claudin 7 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal CLDN7 Primary Antibody für EIA, FACS - ABIN951552
Ouban, Ahmed: Claudins in human cancer: a review. in Histology and histopathology 2009
Zeige alle 3 Referenzen für ABIN951552
Cow (Bovine) Polyclonal CLDN7 Primary Antibody für WB - ABIN2777260
Kleinberg, Holth, Trope, Reich, Davidson: Claudin upregulation in ovarian carcinoma effusions is associated with poor survival. in Human pathology 2008
We identified hepatocyte nuclear factor 4alpha as a regulatory factor that bound endogenous CLDN7 promoter in differentiating intestinal epithelial cells and stimulated CLDN7 promoter activity.
claudin 1 and claudin 4 (zeige CLDN4 Antikörper) are differentially involved in atopic dermatitis pathogenesis
we identified a previously unrecognized function of claudin-7 in regulating cell proliferation and maintaining epithelial cell attachment through engaging integrin beta1.
A variant, rs222857, in the CLDN7 locus, predicted adiponectin (zeige ADIPOQ Antikörper) increases within intensive lifestyle intervention.
CLDN-7 palmitoylation prohibits tight junction integration and fosters glycolipid-enriched membrane domains recruitment. Via associated molecules, palmitoylated CLDN-7supports motility and invasion.
The increased claudin-1 expression was significantly associated with the high pathologic grade, the presence of microscopic perineural invasion, vascular invasion, nodal metastasis, and advanced clinical stage of oral squamous cell carcinoma.
Data show that claudin-4 (zeige CLDN4 Antikörper) and claudin-7 were observed in hepatocytes of severely damaged mouse and human livers.
Data indicate that claudin-7 knockdown cells display decreased anchorage-independent growth.
Loss of claudin-7 potentiates epithelial-to-mesenchymal transition to promote colon cancer, in a manner dependent on Rab25 (zeige RAB25 Antikörper).
Icreased claudin 7 expression was related to decreased survival in nasopharyngeal carcinoma.
The intestine-specific Cldn7 deficiency caused colonic inflammation, even though TJ structures were still present due to other claudins.
Salmonella targets the tight junction protein (zeige OCLN Antikörper) claudin-2 (zeige CLDN2 Antikörper) to facilitate bacterial invasion.
In mice, claudin-7 has non-TJ functions, including maintenance of epithelial cell-matrix interactions and intestinal homeostasis.
TSLP (zeige TSLP Antikörper) induces expression of tight junction protein (zeige OCLN Antikörper) claudin-7 in dendritic cells via NF-kappaB (zeige NFKB1 Antikörper) as well as via TLRs and may control tight junctions of DCs to preserve the epithelial barrier during allergic inflammation
Claudin-7 is essential for NaCl homeostasis in distal nephrons, and the paracellular ion transport pathway plays indispensable roles in keeping ionic balance in kidneys.
claudin-7 was found in the same nephron segments as claudin-8 (zeige CLDN8 Antikörper), but it was expressed primarily at the basolateral membrane
claudin 7 might be involved in vesicle trafficking to the basolateral membrane, possibly stabilizing cytoplasmic vesicles or participating in cell-matrix interactions
Overexpression of claudin-7 is associated with gastric tumorigenesis
the effect of claudin-7 overexpression in LLC-PK1 cells on paracellular transport is mediated through a concurrent decrease in the paracellular conductance to Cl(-) and an increase in the paracellular conductance to Na(+).
These findings indicate that claudin-4 (zeige CLDN4 Antikörper) and -7 may play a role in the gingiva junctional epithelium even in the absence of tight junctions.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
, claudin-like protein ZF4A22
, clostridium perfringens enterotoxin receptor-like 2