Claudin 7 Antikörper (AA 162-211)

Produktnummer ABIN1533163

Der Kaninchen Polyklonal anti-Claudin 7 Antikörper (ABIN1533163) detektiert spezifisch Claudin 7 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Claudin 7 Antikörper (AA 162-211) (ABIN1533163)

Target: Claudin 7 (CLDN7)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Claudin 7 Antikörper

Bindungsspezifität: AA 162-211

Verwendungszweck: Claudin-7 Antibody

Spezifität: Claudin-7 Polyclonal Antibody detects endogenous levels of Claudin-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 7. AA range:162-211

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Claudin 7

Hintergrund:

Synonyms: CLDN7, CEPTRL2, CPETRL2, Claudin-7, CLDN-7

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010],

Gene Name: CLDN7

Protein Name: Claudin-7

Molekulargewicht: 22 kDa

Gen-ID: 1366

OMIM: 609131

UniProt: O95471

Pathways: Hepatitis C