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Chromosome 18 Open Reading Frame 8 Proteine (C18orf8)

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Zusätzlich bieten wir Ihnen C18orf8 Antikörper (65) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
C18orf8 29919 Q96DM3
C18orf8 76482 Q8VC42
Ratte C18orf8 C18orf8 291784  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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C18orf8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Chromosome 18 Open Reading Frame 8 (C18orf8) Interaktionspartnern

Human Chromosome 18 Open Reading Frame 8 (C18orf8) Interaktionspartner

  1. serum GDF15 (zeige GDF15 Proteine) may be a useful diagnostic and prognostic biomarker for colorectal cancer.

  2. These findings highlight an important contribution of GDF15 (zeige GDF15 Proteine) in promoting airway epithelial senescence upon cigarette smoke exposure.

  3. The results of this study, including a robust induction of GDF-15 (zeige GDF15 Proteine) expression by several external factors known to elevate IOP, and rGDF-15-induced increase in contractility, cell adhesion, and the levels of ECM (zeige MMRN1 Proteine) proteins and alphaSMA (zeige ACTA2 Proteine) in TM cells

  4. GDF-15 (zeige GDF15 Proteine) captures distinct aspects of cardiovascular disease development, progression, and prognosis, which are not represented by clinical risk predictors and other biomarkers. The usefulness of GDF-15 (zeige GDF15 Proteine) to guide management decisions and discover new treatment targets should be further explored.

  5. In stable Coronary Heart Disease, GDF-15 (zeige GDF15 Proteine) was independently associated with cardiovascular (CV), non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15 (zeige GDF15 Proteine), therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD (zeige CHDH Proteine).

  6. Impaired glucose tolerance is associated with increased GDF-15 (zeige GDF15 Proteine) levels even in the absence of anemia

  7. GDF15 (zeige GDF15 Proteine) is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (zeige INS Proteine) resistance.

  8. NAG-1 (zeige GDF15 Proteine) expression was transcriptionally upregulated by CHOP (zeige DDIT3 Proteine), which promoted chemokine (zeige CCL1 Proteine) production through sustained NF-kappaB (zeige NFKB1 Proteine) activation.

  9. ChIP studies showed that the S100A4 (zeige S100A4 Proteine) protein binds to the GDF15 (zeige GDF15 Proteine) promoter, implicating S100A4 (zeige S100A4 Proteine) in GDF15 (zeige GDF15 Proteine) regulation at the transcriptional level.

  10. Study compared the diagnostic utility of GDF-15 (zeige GDF15 Proteine) with FGF-21 (zeige FGF21 Proteine) in an adult mitochondrial disease cohort. GDF-15 (zeige GDF15 Proteine) outperforms FGF-21 (zeige FGF21 Proteine) as an indicator of mitochondrial diseases. GDF-15 (zeige GDF15 Proteine) is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 (zeige FGF21 Proteine) seems to be more indicative of mitochondrial disease when muscle manifestations are present

C18orf8 Protein Überblick

Protein Überblick

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Genbezeichner und Symbole assoziert mit C18orf8

  • chromosome 18 open reading frame 8 (C18orf8)
  • chromosome 18 open reading frame 8 (c18orf8)
  • growth differentiation factor 15 (GDF15)
  • RIKEN cDNA 3110002H16 gene (3110002H16Rik)
  • similar to RIKEN cDNA 2400010D15 (RGD1311805)
  • 2400010D15Rik Protein
  • C18orf8 Protein
  • GDF-15 Protein
  • HsT2591 Protein
  • MIC-1 Protein
  • Mic1 Protein
  • NAG-1 Protein
  • PDF Protein
  • PLAB Protein
  • PTGFB Protein

Bezeichner auf Proteinebene für C18orf8

chromosome 18 open reading frame 8 , hypothetical protein LOC100124886 , hypothetical protein LOC100137621 , colon cancer-associated protein Mic1 , uncharacterized protein C18orf8 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , colon cancer-associated protein Mic1 homolog , uncharacterized protein C18orf8 homolog , uncharacterized protein LOC291784

GENE ID SPEZIES
421075 Gallus gallus
100124886 Xenopus (Silurana) tropicalis
100137621 Xenopus laevis
29919 Homo sapiens
9518 Homo sapiens
76482 Mus musculus
291784 Rattus norvegicus
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