anti-Chordin (CHRD) Antikörper

CHRD encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. Zusätzlich bieten wir Ihnen Chordin Kits (10) und Chordin Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CHRD 8646 Q9H2X0
CHRD 12667 Q9Z0E2
CHRD 117275  
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Top anti-Chordin Antikörper auf antikoerper-online.de

Showing 10 out of 82 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using Chordin  Antibody . This demonstrates the CHRD antibody detected the CHRD protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-CHRD Antibody (C-term) (ABIN388176) in HepG2 cell line lysates (35 µg/lane). CHRD(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CHRD antibody (C-term) (ABIN388176), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB CHRD Antibody (N-term) (ABIN388175) western blot analysis in mouse bladder tissue lysates (35 µg/lane).This demonstrates the CHRD antibody detected the CHRD protein (arrow). CHRD Antibody (N-term) (ABIN388175)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Maus Kaninchen Unkonjugiert WB CHRD Antibody (Center)  western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CHRD antibody detected the CHRD protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: Chordin Antibody [NBP1-87513] - Staining of human duodenum shows strong plasma positivity. Immunocytochemistry/Immunofluorescence: Chordin Antibody [NBP1-87513] - Staining of human cell line U-2 OS shows positivity in nucleus & nucleoli. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen APC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen APC IHC, ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA   200 μL Anmelden zum Anzeigen 11 bis 14 Tage
1.203,02 €
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CHRD Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine) ,
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Am meisten referenzierte anti-Chordin Antikörper

  1. Human Polyclonal CHRD Primary Antibody für IHC (p), ELISA - ABIN4369824 : Moll, Millet, Noël, Orsetti, Bardin, Katsaros, Jorgensen, Garcia, Theillet, Pujol, François: Chordin is underexpressed in ovarian tumors and reduces tumor cell motility. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Chordin Interaktionspartner

Rabbit Chordin (CHRD) Interaktionspartner

  1. Data show that BMP-2 (zeige BMP2 Antikörper), BMP-4 (zeige BMP4 Antikörper), and BMP-7 (zeige BMP7 Antikörper), noggin (zeige NOG Antikörper), and chordin were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.

Human Chordin (CHRD) Interaktionspartner

  1. Data suggest CHRD (chordin) cleavage by tolloid-like metalloproteinases is insufficient to regulate BMP(bone morphogenetic protein)/BMPR signaling; CHRD fragments and TSG (twisted gastrulation protein) contribute to inhibition of BMP/BMPR signaling.

  2. C-terminal chordin domains play an important role in Bone morphogenetic protein regulation.

  3. chordin silencing increased osteogenic differentiation without supplemented BMP-2 (zeige BMP2 Antikörper).

  4. results suggest that CHRD could participate in regulating BMP activity in normal ovarian surface epithelium physiology, and that its mis (zeige AMH Antikörper)-expression in ovarian surface epithelium may facilitate cancer incidence and/or progression

  5. Bone morphogenetic protein (BMP) chordin is produced endogenously during osteogenic differentiation of human mesenchymal stem cells (MSCs); blockade of bone morphogenetic inhibitor chordin increases the rate of osteogenic differentiation of MSCs in vitro.

  6. Noggin (zeige NOG Antikörper) and chordin were also expressed most intensely in areas of cartilage formation and there was no difference in their expression between the non-hypertrophic and hypertrophic chondrocytes.

  7. there was no difference in the expression of the noggin (zeige NOG Antikörper) and chordin between healing and nonhealing fractures

  8. Alternatively spliced variants have different patterns of expression to influence BMP activity in varying physiolgical situations.

Mouse (Murine) Chordin (CHRD) Interaktionspartner

  1. Chordin upregulated in primary satellite cell cultures and in regenerating muscles

  2. The data indicate a role for CV2 and Chd in the establishment of the vertebral morphogenetic field through the long-range relocalization of Chd/BMP complexes.

  3. Data show that Brorin-like was predominantly expressed in the adult brain and embryonic neural tissues.

  4. the BMP antagonists chordin and noggin (zeige NOG Antikörper) promote the inductive and trophic activities of rostral organizing centers in early development of the mammalian head

  5. products of Bmp1 (zeige BMP1 Antikörper) and Tll1 (zeige TLL1 Antikörper) are responsible for in vivo cleavage of Chordin in mammals

  6. chordin antagonism of bone morphogenetic protein signaling and cellular uptake of chordin require cell-surface heparan sulfate proteoglycans

  7. results suggest that twisted gastrulation and chordin are involved in osteoblast differentiation and mineralization by regulating BMP signaling

  8. These results demonstrate that the chordin contributes to synaptic plasticity and learning likely through a presynaptic mechanism.

  9. chordin has a role in venous and arterial patterning and the Bone Morphogenetic Protein pathway is necessary for the process

  10. chordin is a modifier for the craniofacial anomalies of Tbx1 (zeige TBX1 Antikörper) mutations.

Zebrafish Chordin (CHRD) Interaktionspartner

  1. activation of the FGF signaling pathway induces the formation of a dorsal axis with a complete head structure through the expression of chd and subsequent maintenance of dkk1b (zeige DKK1 Antikörper) expression levels.

  2. Binding of CV2 (zeige BMPER Antikörper) to Chordin promotes BMP-2 (zeige BMP4 Antikörper) signaling.

  3. Targeted knockdown of Sox17 (zeige SOX17 Antikörper) and Chd in dorsal forerunner cells led to aberrant Left-Right (L-R) asymmetry establishment, as visualized by the expression of southpaw and lefty (zeige LEFTY2 Antikörper), and heart and pancreas placement in the embryo.

  4. Chl (zeige CHRDL2 Antikörper), like Chd, dorsalizes embryos upon overexpression and is cleaved by BMP1 (zeige BMP1 Antikörper); loss-of-function experiments show Chl (zeige CHRDL2 Antikörper) serves as a BMP antagonist with functions that overlap and are redundant with those of Chd in forming the dorsoventral axis.

  5. Data show that The inhibition of Brorin-like functions in zebrafish resulted in the impairment of neural development.

  6. by regulating the expression of her5, the Bmp2b (zeige BMP4 Antikörper)/Chordin gradient directs the anteroposterior patterning of endoderm in zebrafish embryos

  7. chd, a bone morphogenetic protein antagonist expressed in gastrulation, is dispensable for neural crest induction.

  8. Twisted (zeige POMT2 Antikörper) gastrulation enhances BMP signaling through chordin dependent and independent mechanisms

  9. specification of anterior neural tissue requires later activities of Chordin and mesodermal factors.

  10. While Chordin is the main player of the D/V axis, the structures remaining in the chd mutant in both mesodermal and ectodermal layers) result from the anti-Bmp activity carried by Nog1 (zeige NOG Antikörper) and Fstl2 (zeige IGFBP7 Antikörper) at blastula and gastrula stages.

Xenopus laevis Chordin (CHRD) Interaktionspartner

  1. Chordin protein formed a smooth gradient that encircled the embryo, reaching the ventral-most Brachet cleft.

  2. This study demonstrates a crucial role of Sizzled in coupling dorsal-ventral axis size information with Chordin stability.

  3. Chordin, Noggin (zeige NOG Antikörper), beta-Catenin (zeige CTNNB1 Antikörper), and Cerberus (zeige CER1 Antikörper) have roles in neural induction in Xenopus

  4. Bone morphogenetic protein 4 (zeige BMP4 Antikörper) knockdown was sufficient to rescue the ventralizing effects caused by loss of Chordin activity.

  5. complex containing Smicl and the newly induced Xlim1 (zeige LHX1 Antikörper) induces expression of Chordin

  6. Several lines of evidence support the hypothesis that chordin influences pronephros development by directing the formation of anterior somites.

  7. Embryo elongation can occur through the synergistic effect(s) of the organizer molecule chordin, and each of the 'verall posteriorizing molecules'eFGF, VegT and Xbra.

  8. Xld (zeige TLL2 Antikörper) cleaves Chordin, an inhibitory binding protein for BMP2/4 (zeige BMP4 Antikörper), releasing fragments with reduced affinity for these important ventralizing signals.

  9. CV2/Chordin interaction may help coordinate bone morphogenetic protein (BMP) diffusion to the ventral side of the embryo, ensuring that BMPs liberated from Chordin inhibition by tolloid proteolysis cause peak signaling levels.

  10. Study shows that Xenopus ONT1 (zeige OLFML3 Antikörper), an Olfactomedin-class secreted protein, stabilizes axial formation by restricting Chordin activity on the dorsal side. [ONT1 (zeige OLFML3 Antikörper)]

Chordin (CHRD) Antigen-Profil

Protein Überblick

This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.

Genbezeichner und Symbole assoziert mit anti-Chordin (CHRD) Antikörper

  • chordin (CHRD) Antikörper
  • chordin (CHD) Antikörper
  • chordin (chrd) Antikörper
  • chordin protein (chordin) Antikörper
  • chordin (Chrd) Antikörper
  • chordin (chd) Antikörper
  • Chd Antikörper
  • chordino Antikörper
  • wu:fe47d04 Antikörper
  • X-chordin Antikörper

Bezeichner auf Proteinebene für anti-Chordin (CHRD) Antikörper

chordin , chordin protein , din , dino (din) , fe47d04 , protein chordino , organizer-specific secreted-dorsalizing factor

GENE ID SPEZIES
100067164 Equus caballus
100008933 Oryctolagus cuniculus
395828 Gallus gallus
549011 Xenopus (Silurana) tropicalis
778563 Ciona intestinalis
8646 Homo sapiens
12667 Mus musculus
117275 Rattus norvegicus
30161 Danio rerio
607289 Canis lupus familiaris
509942 Bos taurus
398045 Xenopus laevis
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