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Cartilage Associated Protein Proteine (CRTAP)

The protein encoded by CRTAP is similar to the chicken and mouse CRTAP genes. Zusätzlich bieten wir Ihnen CRTAP Antikörper (69) und CRTAP Kits (14) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CRTAP 10491 O75718
CRTAP 56693 Q9CYD3
Ratte CRTAP CRTAP 363158  
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Showing 7 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.533,50 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   20 μg Anmelden zum Anzeigen 6 bis 8 Tage
379,93 €
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HOST_Escherichia coli (E. coli) Maus GST tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
Details

CRTAP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine) ,
,

Weitere Proteine zu Cartilage Associated Protein (CRTAP) Interaktionspartnern

Human Cartilage Associated Protein (CRTAP) Interaktionspartner

  1. This study enhances our knowledge about the mutational pattern of the LEPRE1 (zeige LEPRE1 Proteine), CRTAP, and PPIB (zeige PPIB Proteine) genes. LEPRE1 (zeige LEPRE1 Proteine) should be the first gene analyzed in mutation detection studies in patients with recessive OI.

  2. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro.

  3. SNP rs7623768 and the haplotype G-C of rs4076086-rs7623768 in CRTAP were associated with femoral neck bone mineral density (p = 0.009 and p = 0.003, respectively).

  4. Importantly, human mutations in the CRTAP gene have been associated with recessive forms of OI.

  5. CRTAP deficiency results in higher bone mineral content of the bone matrix in osteogenesis imperfecta type VII.

  6. Null mutations in LEPRE1 (zeige LEPRE1 Proteine) and CRTAP cause severe recessive osteogenesis imperfecta (zeige COL1A2 Proteine).

  7. CRTAP and P3H1 (zeige LEPRE1 Proteine) are mutually stabilized in the collagen prolyl 3-hydroxylation complex in endoplasmic reticulum.

  8. CRTAP mutations not described earlier were identified in 10 individuals who had a clinical diagnosis of lethal and severe osteogenesis imperfecta (zeige COL1A2 Proteine).

  9. complexes with prolyl 3-hydroxylase 1 (P3H1) to decrease prolyl 3 hydroxylation; dysregulation (zeige COL1A2 Proteine) of prolyl 3 hydroxylation is a (zeige TH Proteine) mechanism for connective tissue disease

  10. Screening of 78 subjects diagnosed with osteogenesis imperfecta (zeige COL1A2 Proteine) type II or III, identified three probands with mutations in CRTAP and 16 with mutations in LEPRE1 (zeige LEPRE1 Proteine).

Mouse (Murine) Cartilage Associated Protein (CRTAP) Interaktionspartner

  1. This substitution abolished P3h1 (zeige LEPRE1 Proteine) activity but retained ability to form a complex with Crtap and thus the collagen chaperone function.

  2. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro.

  3. In Crtap-deficient mice, the mineral content of the bone matrix is abnormally high; there are increased mineral densities at all measured sites for murine femora compared to control animals.

  4. CRTAP mutations are associated with the clinical spectrum of recessive osteogenesis imperfecta (zeige COL1A2 Proteine), including the type II and VII (zeige TH Proteine) forms

CRTAP Protein Überblick

Protein Überblick

The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.

Genbezeichner und Symbole assoziert mit CRTAP

  • cartilage associated protein (crtap)
  • cartilage associated protein (CRTAP)
  • cartilage associated protein (AaeL_AAEL011159)
  • cartilage associated protein (CpipJ_CPIJ013810)
  • cartilage associated protein (Crtap)
  • 5730529N23Rik Protein
  • CASP Protein
  • Leprel3 Protein
  • OI7 Protein
  • RGD1565180 Protein
  • wu:fb47h01 Protein
  • zgc:85621 Protein

Bezeichner auf Proteinebene für CRTAP

cartilage-associated protein , cartilage associated protein , leprecan-like 3 , dualin

GENE ID SPEZIES
406626 Danio rerio
540924 Bos taurus
549401 Xenopus (Silurana) tropicalis
5574430 Aedes aegypti
6046617 Culex quinquefasciatus
10491 Homo sapiens
56693 Mus musculus
395992 Gallus gallus
363158 Rattus norvegicus
485577 Canis lupus familiaris
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