CUB Domain Containing Protein 1 Proteine (CDCP1)

The protein encoded by CDCP1 is a transmembrane protein containing three extracellular CUB domains. Zusätzlich bieten wir Ihnen CUB Domain Containing Protein 1 Antikörper (183) und CUB Domain Containing Protein 1 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CDCP1 64866 Q9H5V8
CDCP1 109332 Q5U462
Ratte CDCP1 CDCP1 301082  
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Top CUB Domain Containing Protein 1 Proteine auf antikoerper-online.de

Showing 10 out of 17 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Maus His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
Details
HOST_Human Cells Human Fc Tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
Details
HOST_Human Cells Rhesusaffen His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Human Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
214,29 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
412,50 €
Details
HOST_Wheat germ Human Unkonjugiert   10 μg Anmelden zum Anzeigen 7 bis 8 Tage
576,00 €
Details

CDCP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, , , , ,
Mouse (Murine) ,
, ,

Am meisten referenzierte CUB Domain Containing Protein 1 Proteine

  1. Rhesus Monkey CDCP1 Protein expressed in Human Cells - ABIN2010111 : Conze, Lammers, Kuci, Scherl-Mostageer, Schweifer, Kanz, Buhring: CDCP1 is a novel marker for hematopoietic stem cells. in Annals of the New York Academy of Sciences 2003 (PubMed)
    Zeige alle 2 Referenzen für 2010111

  2. Human CDCP1 Protein expressed in Human Cells - ABIN2005620 : Scherl-Mostageer, Sommergruber, Abseher, Hauptmann, Ambros, Schweifer: Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. in Oncogene 2001 (PubMed)
    Zeige alle 2 Referenzen für 2005620

  3. Human CDCP1 Protein expressed in HEK-293 Cells - ABIN2713643 : Sandercock, Rust, Guillard, Sachsenmeier, Holoweckyj, Hay, Flynn, Huang, Yan, Herpers, Price, Soden, Freeth, Jermutus, Hollingsworth, Minter: Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling. in Molecular cancer 2015 (PubMed)

Weitere Proteine zu CUB Domain Containing Protein 1 (CDCP1) Interaktionspartnern

Human CUB Domain Containing Protein 1 (CDCP1) Interaktionspartner

  1. These studies have important implications for the development of a therapeutic to block CDCP1 activity and Triple-negative breast cancer (TNBC)metastasis.

  2. CDCP1 may facilitate loss of adhesion by promoting activation of EGFR (zeige EGFR Proteine) and Src (zeige SRC Proteine) at sites of cell-cell and cell-substratum contact.

  3. Stromal expression patterns for both ADAM12 (zeige ADAM12 Proteine) and CDCP1.

  4. these data demonstrated that HIF-2alpha (zeige EPAS1 Proteine) could promote hepatocellular carcinoma cell migration by regulating CDCP1

  5. Our results establish that differential glycosylation, cell surface presentation and extracellular expression of CDCP1 are hallmarks of prostate cancer progression.

  6. High CDCP1 expression is associated with Colorectal Cancer.

  7. ADAM9 (zeige ADAM9 Proteine) enhances CDCP1 protein expression by suppressing miR (zeige MLXIP Proteine)-218 for lung tumor metastasis

  8. Elevated CDCP1 was observed in 77% of HGSC cases. Silencing of CDCP1 reduced migration and non-adherent cell growth in vitro and tumour burden in vivo.

  9. CDCP1 protein plays an important role in the progression of ovarian clear cell carcinoma. Elevated CDCP1 levels correlates with poor patient outcome in ovarian clear cell carcinoma patients.

  10. CDCP1 overexpression enhances HER2 (zeige ERBB2 Proteine) activity. CDCP1 binds to HER2 (zeige ERBB2 Proteine), promoting SRC (zeige SRC Proteine)-HER2 (zeige ERBB2 Proteine) crosstalk.

Mouse (Murine) CUB Domain Containing Protein 1 (CDCP1) Interaktionspartner

  1. Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor (zeige RYK Proteine) cross-talk in unanchored cells.

  2. established mechanism for initiation of CDCP1-mediated signaling; demonstrated that processing of surface CDCP1 by extracellular serine proteases is prerequisite for CDCP1-dependent survival of cancer cells during metastasis; preventing cleavage of CDCP1 abrogated survival signaling associated with CDCP1 and induced PARP1 (zeige PARP1 Proteine) cleavage and PARP1 (zeige PARP1 Proteine)-mediated apoptosis

  3. CDCP1 may have a role in neoplasm metastasis; targeting it with a monoclonal antibody inhibits metastasis in a prostate cancer model

CUB Domain Containing Protein 1 (CDCP1) Protein Überblick

Protein Überblick

The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Genbezeichner und Symbole assoziert mit CDCP1

  • CUB domain containing protein 1 (CDCP1)
  • CUB domain containing protein 1 (Cdcp1)
  • 9030022E12Rik Protein
  • AA409659 Protein
  • CD318 Protein
  • E030027H19Rik Protein
  • RGD1305578 Protein
  • SIMA135 Protein
  • TRASK Protein

Bezeichner auf Proteinebene für CDCP1

CUB domain-containing protein 1 , membrane glycoprotein gp140 , subtractive immunization M plus HEp3-associated 135 kDa protein , transmembrane and associated with src kinases

GENE ID SPEZIES
64866 Homo sapiens
109332 Mus musculus
301082 Rattus norvegicus
420703 Gallus gallus
484797 Canis lupus familiaris
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