C-Type Lectin Domain Family 4, Member A Proteine (CLEC4A)

CLEC4A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 4, Member A Antikörper (72) und C-Type Lectin Domain Family 4, Member A Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CLEC4A 50856 Q9UMR7
Ratte CLEC4A CLEC4A 474143  
CLEC4A 26888 Q9QZ15
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Top C-Type Lectin Domain Family 4, Member A Proteine auf antikoerper-online.de

Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details

CLEC4A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)
,

Am meisten referenzierte C-Type Lectin Domain Family 4, Member A Proteine

  1. Human CLEC4A Protein expressed in Human Cells - ABIN2004301 : Bates, Fournier, Garcia, Valladeau, Durand, Pin, Zurawski, Patel, Abrams, Lebecque, Garrone, Saeland: APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Zeige alle 3 Referenzen für 2004301

Weitere Proteine zu C-Type Lectin Domain Family 4, Member A (CLEC4A) Interaktionspartnern

Human C-Type Lectin Domain Family 4, Member A (CLEC4A) Interaktionspartner

  1. DCIR SNP rs2377422 is a novel genetic susceptibility factor for both SLE and primary SS.

  2. this study shows that sulfo-Lewis(a) is a high affinity ligand for DCIR and that DCIR interacts with ligands from both pathogenic and endogenous origin of which most are shared by DC-SIGN (zeige CD209 Proteine).

  3. No association was found between our inflammatory bowel disease cohort and the candidate single nucleotide polymorphisms for DCIR (CD/HC: P=0.22 and UC/HC: P=0.41)

  4. Data provide evidence for association between DCIR rs2377422 and RA in non-Caucasian populations and confirm the influence of DCIR polymorphisms on RA susceptibility, especially on ACPA (zeige PRTN3 Proteine)-negative RA.

  5. An involvement of ITIM domain in HIV-1-mediated signaling events and a relationship between phosphorylation events and DCIR function with respect to HIV-1 biology.

  6. Data show that antigen targeting via the DCIR receptor allows activation of specific CD8 (zeige CD8A Proteine)(+) T-cell immunity.

  7. CLECSF6 is involved in the control of inflammation in neutrophils

  8. The phosphorylation of SHP-2 (zeige PTPN11 Proteine) by GM-CSF (zeige CSF2 Proteine) promotes the binding of SHP-2 (zeige PTPN11 Proteine) to the GM-CSF (zeige CSF2 Proteine) receptor to the disadvantage of CLECSF6.

  9. Human APLEC and DCIR may be associated with susceptibility to anti-CCP (zeige CRYGD Proteine)-negative rheumatoid arthritis.

  10. The data show that targeting of DCIR can modulate human plasmacytoid dendritic cell function and may be applied in disease prevention and treatment.

Mouse (Murine) C-Type Lectin Domain Family 4, Member A (CLEC4A) Interaktionspartner

  1. this study shows that upon injection of d-galactosamine and lipopolysaccharide, Dcir1-/- mice show decreased mortality rates and serum levels of alanine aminotransferase (zeige ALT Proteine)

  2. Dcir1 enhances the pathogenesis of DSS (zeige PMP22 Proteine) colitis by altering neutrophil recruitment and their functions.

  3. While DCIR1 was ubiquitously expressed on myeloid cells in various immune organs, significant expression of DCAR2 was detected only on subpopulations of conventional dendritic cells from bone marrow and skin-draining lymph nodes.

  4. MCL (zeige CLEC4D Proteine)-/- as well as DCIR-/- mice exhibited only a slightly increased severity of disease compared to wild-type mice indicating a limited role for MCL (zeige CLEC4D Proteine) and DCIR in the regulation of intestinal immunity.

  5. our findings show that DCIR plays an important role in maintaining bone homeostasis.

  6. DCIR is a novel receptor for IVIg, mediating interaction of innate and adaptive immunity in tolerogenic responses.

  7. This study indicates that DCIR is critically involved in Cerebral malaria induction

  8. These results suggest that DCIR plays a protective role in limiting the Chikungunya virus-induced inflammatory response and subsequent tissue and joint damage.

  9. These observations indicate that Dcir is a negative regulator of dendritic cell expansion and has a crucial role in maintaining the homeostasis of the immune system.

C-Type Lectin Domain Family 4, Member A (CLEC4A) Protein Überblick

Protein Überblick

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Genbezeichner und Symbole assoziert mit CLEC4A

  • C-type lectin domain family 4, member A (CLEC4A)
  • C-type lectin domain family 4, member A (Clec4a)
  • C-type lectin domain family 4, member a2 (Clec4a2)
  • Clec4a Protein
  • Clecsf6 Protein
  • DCIR Protein
  • Dcir1 Protein
  • DDB27 Protein
  • LLIR Protein

Bezeichner auf Proteinebene für CLEC4A

C-type lectin domain family 4, member A , C-type lectin, superfamily member 6 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 , C-type lectin DDB27 , C-type lectin domain family 4 member A , C-type lectin superfamily member 6 , dendritic cell immunoreceptor , lectin-like immunoreceptor , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6 , dendritic cell inhibitory receptor 1

GENE ID SPEZIES
748392 Pan troglodytes
50856 Homo sapiens
474143 Rattus norvegicus
26888 Mus musculus
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