anti-BCL2-Associated Athanogene 3 (BAG3) Antikörper

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. Zusätzlich bieten wir Ihnen BAG3 Proteine (19) und BAG3 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BAG3 9531 O95817
BAG3 29810 Q9JLV1
BAG3 293524  
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Top anti-BAG3 Antikörper auf antikoerper-online.de

Showing 10 out of 127 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BAG3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: BAG3 Antibody [NBP2-15543] - Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution. Western Blot: BAG3 Antibody [NBP2-15543] - BAG3 antibody detects BAG3 protein by Western blot analysis. A. 50 ug mouse heart lysate/extract 7. 5 % SDS-PAGEBAG3 antibody dilution: 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- Bag3 Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Bag3 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-Bag3 antibody, Western blotting Lane 1: MCF-7 Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: A549 Cell Lysate Lane 4: HELA Cell Lysate Lane 5: COLO320 Cell Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Ziege Unkonjugiert ELISA, WB Antibody (0.1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (fro), IHC (p), IP, SimWes, WB Simple Western: BAG3 Antibody [NBP2-27398] - Simple Western lane view shows a specific band for BAG3 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Frozen: BAG3 Antibody [NBP2-27398] - Frozen mouse muscle tissue section stained for BAG-3 expression using NBP2-27398 at 1:2000. The tissue section was fixed in 3.8% paraformaldehyde prior to staining. BAG-3 localizes with Z-disk proteins. 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ISt, IHC (p), WB WB Image BAG3 antibody detects BAG3 protein by Western blot analysis. A. 30 µg K562 whole cell lysate/extract 7.5 % SDS-PAGE BAG3 antibody , dilution: 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using BAG3, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: MCF-7 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Ziege Unkonjugiert IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details

BAG3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-BAG3 Antikörper

  1. Human Polyclonal BAG3 Primary Antibody für ICC, IF - ABIN4282959 : Goldman, Chen, Roesly, Hill, Tome, Dvorak, Bernstein, Dvorak: Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis. in American journal of physiology. Gastrointestinal and liver physiology 2011 (PubMed)
    Zeige alle 4 Referenzen für 4282959

  2. Human Polyclonal BAG3 Primary Antibody für IHC, ELISA - ABIN1452054 : Lee, Takahashi, Yasuhara, Inazawa, Kamada, Tsujimoto: Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death. in Oncogene 2000 (PubMed)
    Zeige alle 2 Referenzen für 1452054

  3. Cow (Bovine) Polyclonal BAG3 Primary Antibody für WB - ABIN2783302 : Franceschelli, Rosati, Lerose, De Nicola, Turco, Pascale: Bag3 gene expression is regulated by heat shock factor 1. in Journal of cellular physiology 2008 (PubMed)

  4. Human Polyclonal BAG3 Primary Antibody für ELISA, WB - ABIN184770 : Doong, Price, Kim, Gasbarre, Probst, Liotta, Blanchette, Rizzo, Kohn: CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70. in Oncogene 2000 (PubMed)

  5. Human Polyclonal BAG3 Primary Antibody für IHC, IHC (p) - ABIN4282955 : Nymoen, Hetland Falkenthal, Holth, Ow, Ivshina, Tropé, Kuznetsov, Staff, Davidson: Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma. in Gynecologic oncology 2015 (PubMed)

Weitere Antikörper gegen BAG3 Interaktionspartner

Zebrafish BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (zeige FLNC Antikörper)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  2. findings showed that the P209L mutation causes BAG3 to aggregate; proposed that the gradual loss of available BAG3(wt) and BAG3(P209L) proteins results in insufficiency leading to myofibrillar disintegration

Human BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  2. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (zeige FLNC Antikörper)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  3. variants in TNNT2 (zeige TNNT2 Antikörper) and BAG3 are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  4. It has been demonstrated that HSPB8 (zeige HSPB8 Antikörper)-BAG3-HSP70 (zeige HSP70 Antikörper) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

  5. The authors propose that the chaperone-mediated autophagy function of BAG3 represents a specific host defense strategy to counteract the function of VP40 in promoting efficient egress and spread of virus particles.

  6. BAG3 bound to Hsp70 (zeige HSP70 Antikörper) at the same time as Hsp22 (zeige HSPB8 Antikörper), Hsp27 (zeige HSPB1 Antikörper), or alphaB-crystallin (zeige CRYAB Antikörper), suggesting that it might physically bring the chaperone families together into a complex.

  7. These results suggest that Bag1 (zeige BAG1 Antikörper) and Bag3 control the stability of the Hsc70 (zeige HSPA8 Antikörper)-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 (zeige HSPA8 Antikörper) system.

  8. we report the first mammalian model of a single amino acid mutation of BAG3 (P209L) in exon 3 of Bag3 associated with the development of muscle disease with left ventricular dysfunction and heart failure

  9. High BAG3 expression Correlates with Sebaceous Gland Carcinoma of the Eyelid.

  10. These results indicate a possible role for BAG3 protein in the maintenance of cell survival in endometrioid endometrial cancer.

Mouse (Murine) BCL2-Associated Athanogene 3 (BAG3) Interaktionspartner

  1. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  2. Genetic variation in BAG3 plays an important role in the prevention of ischemic tissue necrosis.

  3. The aim of this study was to investigate the possible hemodynamic effects of BAG3 performing both in vitro and in vivo experiments.

  4. Our findings that BAG3 is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (zeige CA2 Antikörper)+) channel provide novel insight into the role of BAG3 in cardiomyopathies and increased arrhythmia risks in heart failure.

  5. molecular association of MyHC (zeige MYH13 Antikörper) and BIS is necessary for MyHC (zeige MYH13 Antikörper) stabilization in skeletal muscle.

  6. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

  7. Bis is upregulated in astrocytes after hypoxia-ischemia; hypoxia-ischemia induces progressive cell death in the hippocampi of bis-positive mice, while hippocampal neurons are less vulnerable to hypoxia-ischemia in mice that lack Bis.

  8. Deletion of the bis gene results in a marked increase in the production of corticosterone that is associated with thymic atrophy.

  9. BAG3 and Hsc70 (zeige HSPA8 Antikörper) interact with actin capping protein (zeige TMOD4 Antikörper) CapZ (zeige CAPZA1 Antikörper) to maintain myofibrillar integrity under mechanical stress.

  10. Results indicate that Bis functions to mediate cellular regulation of the stem cell niche on the vascular compartment.

BAG3 Antigen-Profil

Protein Überblick

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Genbezeichner und Symbole assoziert mit BAG3

  • BCL2-associated athanogene 3 (bag3-A) Antikörper
  • BCL2-associated athanogene 3 (bag3) Antikörper
  • BCL2-associated athanogene 3 (BAG3) Antikörper
  • BCL2-associated athanogene 3 (LOC100228262) Antikörper
  • BCL-2-associated athanogene 3 (BAG3) Antikörper
  • BCL2-associated athanogene 3 (Bag3) Antikörper
  • Bcl2-associated athanogene 3 (Bag3) Antikörper
  • BCL2-associated athanogene 3 (LOC100358030) Antikörper
  • AA407278 Antikörper
  • ATBAG3 Antikörper
  • BAG-3 Antikörper
  • BAG3 Antikörper
  • bag3-A Antikörper
  • BCL-2-associated athanogene 3 Antikörper
  • Bis Antikörper
  • CAIR-1 Antikörper
  • MFM6 Antikörper
  • mg638 Antikörper
  • MGC53113 Antikörper
  • T28J14.160 Antikörper
  • T28J14_160 Antikörper
  • zgc:100859 Antikörper

Bezeichner auf Proteinebene für BAG3

BCL2-associated athanogene 3 , BAG family molecular chaperone regulator 3 , BAG family molecular chaperone regulator 3-like , BCL2-binding athanogene 3 , bcl-2-binding protein Bis , docking protein CAIR-1 , BAG-3 , Bcl-2-binding protein Bis , Bcl-2-interacting death suppressor , bcl-2-associated athanogene 3

GENE ID SPEZIES
379174 Xenopus laevis
445139 Danio rerio
450778 Pan troglodytes
714420 Macaca mulatta
100145358 Xenopus (Silurana) tropicalis
100228262 Taeniopygia guttata
100481230 Ailuropoda melanoleuca
830613 Arabidopsis thaliana
9531 Homo sapiens
29810 Mus musculus
293524 Rattus norvegicus
486916 Canis lupus familiaris
782633 Bos taurus
423931 Gallus gallus
100156989 Sus scrofa
100358030 Oryctolagus cuniculus
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