anti-Atrophin 1 (ATN1) Antikörper

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. Zusätzlich bieten wir Ihnen Atrophin 1 Proteine (4) und Atrophin 1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ATN1 1822 P54259
ATN1 13498 O35126
ATN1 29515 P54258
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Top anti-Atrophin 1 Antikörper auf antikoerper-online.de

Showing 10 out of 31 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: ATN1 Sample Type: 721_B Antibody Dilution: 1.0ug/ml  There is BioGPS gene expression data showing that ATN1 is expressed in 721_B WB Suggested Anti-ATN1 Antibody  Positive Control: Lane1: 30ug human fibroblasts  Primary Antibody Dilution :  1:500 Secondary Antibody :  Anti-rabbit-HRP  Secondry Antibody Dilution :  1:1000 Submitted by: Anonymous 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: ATN1 Antibody [NBP1-90044] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells. Immunocytochemistry/Immunofluorescence: ATN1 Antibody [NBP1-90044] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of Atrophin-1 expression in K562 (A), EOC20 (B), HeLa (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged ATN1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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Human Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Human Kaninchen Unkonjugiert IP 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
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ATN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Am meisten referenzierte anti-Atrophin 1 Antikörper

  1. Human Polyclonal Atrophin 1 Primary Antibody für ICC, IF - ABIN4282207 : Zhang, Xu, Yuan, Sun, Xu: Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance. in Nature communications 2014 (PubMed)

Weitere Antikörper gegen Atrophin 1 Interaktionspartner

Human Atrophin 1 (ATN1) Interaktionspartner

  1. Data indicate that the size of the expanded CAG repeats od dentatorubral-pallidoluysian atrophy protein (DRPLA) was inversely correlated with the age at onset.

  2. Epigenetic regulation of ATN1 by LSD1 (zeige KDM1A Antikörper) is required for cortical progenitor maintenance.

  3. Juvenile myoclonic epilepsy is not associated with the DRPLA gene in a European population.

  4. These data demonstrate that the expanded trinucleotide repeat within ATN-1 mRNA is a potential target for compounds designed to achieve allele-selective inhibition of ATN-1 protein, and one agent may allow the targeting of multiple disease genes.

  5. results suggest that expanded polyQ repeats in ATN1 may contribute to neurodegeneration via alterations in both protein aggregation and intracellular localization.

  6. This study demonistrated that hypoalbuminemia in early onset DRPLA revealed the possibility of multiorgan involvement.

  7. In cerebrum and cerebellum of DRPLA transgenic mouse lines at 4, 8, and 12 weeks it is demonstrated that both the number and expression levels of the altered genes are highly dependent on CAG repeat (zeige CELF3 Antikörper) length and age in both brain regions.

  8. This study demonistrated that Atn1 is response for Dentatorubral-pallidoluysian atrophy.

  9. This sttudy suggested that age-dependent and CAG repeat (zeige CELF3 Antikörper)-dependent intranuclear accumulation of mutant DRPLA leading to nuclear dysfunctions are suggested to be the essential pathophysiologic mechanisms in Dentatorubral-pallidoluysian atrophy.

  10. Atrophin-1 promote neurodegeneration with autophagic hallmarks both in neuronal photoreceptors and glial cells.

Mouse (Murine) Atrophin 1 (ATN1) Interaktionspartner

  1. These results support the model that poly-Q expanded Atrophin-1 proteins cause dentatorubral-pallidoluysian atrophy in a manner independent of any functional interaction with wild-type Atrophin-1 proteins.

  2. TLX (zeige NR2E1 Antikörper) interacts with atrophin1 (Atn1), a corepressor that is involved in human neurodegenerative dentatorubral-pallidoluysian atrophy (DRPLA) and that is essential for development of multiple tissues.

  3. Atrophin-1 and the short form of Atrophin-2 (zeige RERE Antikörper) can act as potent and evolutionarily conserved transcriptional activators.

  4. Fat1 and Atrs 1,2 act in concert after vascular injury but show further that distinct Atr isoforms have disparate effects on VSMC directional migration.

Atrophin 1 (ATN1) Antigen-Profil

Protein Überblick

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Genbezeichner und Symbole assoziert mit anti-Atrophin 1 (ATN1) Antikörper

  • atrophin 1 (ATN1) Antikörper
  • atrophin 1 (Atn1) Antikörper
  • ATN1 Antikörper
  • Atr1 Antikörper
  • atrophin-1 Antikörper
  • B37 Antikörper
  • D12S755E Antikörper
  • Drpla Antikörper
  • HRS Antikörper
  • NOD Antikörper
  • RERE Antikörper

Bezeichner auf Proteinebene für anti-Atrophin 1 (ATN1) Antikörper

arginine-glutamic acid dipeptide (RE) repeats , atrophin-1 , atrophin 1 , dentatorubral-pallidoluysian atrophy protein , dentatorubral pallidoluysian atrophy , dentatorubral-pallidoluysian atrophy protein homolog

GENE ID SPEZIES
513125 Bos taurus
611608 Canis lupus familiaris
722114 Macaca mulatta
100349239 Oryctolagus cuniculus
100599977 Nomascus leucogenys
1822 Homo sapiens
13498 Mus musculus
29515 Rattus norvegicus
427946 Gallus gallus
611607 Canis lupus familiaris
451803 Pan troglodytes
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