Atrophin 1 Antikörper (AA 81-130)

Produktnummer ABIN1451055

Der Kaninchen Polyklonal anti-Atrophin 1 Antikörper (ABIN1451055) detektiert spezifisch Atrophin 1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Atrophin 1 Antikörper (AA 81-130) (ABIN1451055)

Target: Atrophin 1 (ATN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Atrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Atrophin 1 Antikörper

Bindungsspezifität: AA 81-130

Verwendungszweck: Atrophin-1 Antibody

Spezifität: Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ATN1. AA range:81-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Atrophin 1

Target: Atrophin 1 (ATN1)

Andere Bezeichnung: ATN1

Hintergrund:

Synonyms: ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy protein

Background: Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Jul 2016],

Gene Name: ATN1

Protein Name: Atrophin-1

Molekulargewicht: 124 kDa

Gen-ID: 1822

OMIM: 125370

UniProt: P54259