anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) Antikörper

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. Zusätzlich bieten wir Ihnen ASH2L Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ASH2L 9070 Q9UBL3
ASH2L 23808 Q91X20
ASH2L 290829  
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Top anti-ASH2L Antikörper auf antikoerper-online.de

Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ASH2L Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ASH2L Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ASH2L Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Detection of Human ASH2 by Western Blot. Samples: Whole cell lysate (A. 40 mcg – E, 10 mcg – T) from 293T cells that were mock transfected (E) or transfected with an ASH2 expression construct (T). Antibody: ABIN153193 used at the indicated concentrations. Detection: Chemiluminescence with a 10 second exposure. Immunohistochemistry-Paraffin: ASH2L Antibody [ABIN153193] - FFPE section of mouse squamous cell carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert ChIP, IHC (p), IP, IHC, PLA, WB Detection of Human ASH2 by Western Blot and Immunoprecipitation. Samples: A. Whole cell lysate (A. 40 mcg – E, 10 mcg – T) from 293T cells that were mock transfected (E) or transfected with an ASH2 expression construct (T). B. Whole cell lysate (100 mcg – input, one 10 cm plate – IP) from untreated 293T cells. Antibodies: ABIN153190 used at the indicated concentrations for WB (A) and 5 mcg/plate for IP (1/3 of immunoprecipitate was loaded, B). Immunoprecipitated ASH2 was detected by WB using affinity purified rabbit anti-ASH2 antibody (ABIN153191) used at 2 mcg/ml. Detection: Chemiluminescence with exposures times as indicated (A) or 1 minute (B). Immunohistochemistry-Paraffin: ASH2L Antibody [ABIN153190] - Human laryngeal squamous cell carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$306.90
Details
Human Kaninchen Unkonjugiert ChIPSeq, ChIP, WB ASH2L antibody (pAb) tested by ChIP-Seq. ChIP was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 ug of chromatin from undifferentiated hESC cells and 10 µl of antibody. ChIP DNA was sequenced on the Illumina HiSeq and 20 million sequence tags were mapped to identify ASH2L binding sites. The image shows binding across a region of chromosome 12. You can view the complete data set in the UCSC Genome Browser, starting at this specific location, here. ASH2L pAb tested by Western blot. ASH2L detection by Western blot. The analysis of ASH2L was performed using HeLa nuclear extract and ASH2L pAb at a 1:2,000 dilution. 200 μL Anmelden zum Anzeigen 1 bis 2 Tage
$406.00
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with ASH2L antibody ABIN462194 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with ASH2L antibody ABIN462194 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Ratte Unkonjugiert ICC, IF, IP, IHC, WB   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details

ASH2L Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ASH2L Antikörper

  1. Human Polyclonal ASH2L Primary Antibody für ChIP, IHC (p) - ABIN153190 : Rozenblatt-Rosen, Hughes, Nannepaga, Shanmugam, Copeland, Guszczynski, Resau, Meyerson: The parafibromin tumor suppressor protein is part of a human Paf1 complex. in Molecular and cellular biology 2005 (PubMed)
    Show all 12 Pubmed References

  2. Human Polyclonal ASH2L Primary Antibody für ChIPSeq, ChIP - ABIN3434035 : Cao, Chen, Cierpicki, Liu, Basrur, Lei, Dou: An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. in PLoS ONE 2010 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal ASH2L Primary Antibody für IHC (p), IHC - ABIN153193 : Stoller, Huang, Tan, Huang, Zhou, Yang, Gelb, Epstein: Ash2l interacts with Tbx1 and is required during early embryogenesis. in Experimental biology and medicine (Maywood, N.J.) 2010 (PubMed)

  4. Human Monoclonal ASH2L Primary Antibody für ICC, IF - ABIN2668901 : Lüscher-Firzlaff, Gawlista, Vervoorts, Kapelle, Braunschweig, Walsemann, Rodgarkia-Schamberger, Schuchlautz, Dreschers, Kremmer, Lilischkis, Cerni, Wellmann, Lüscher: The human trithorax protein hASH2 functions as an oncoprotein. in Cancer research 2008 (PubMed)

Weitere Antikörper gegen ASH2L Interaktionspartner

Human Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) Interaktionspartner

  1. Data suggest an interplay between megakaryocytic leukemia 1 (MKL1 (zeige MKL1 Antikörper)) and ASH2 protein to promote tumor necrosis factor alpha (TNF-alpha (zeige TNF Antikörper)) induced proinflammatory transcription in macrophages.

  2. the histone methyltransferase core enzyme ASH2L was bound at EGFR (zeige EGFR Antikörper) in the germinal matrix and in gliomas where levels of H3K4me3 are high, and the histone acetyltransferase P300 (zeige EP300 Antikörper) was bound in samples with H3K27ac enrichment

  3. Ash2L acts in concert with P53 promoter occupancy to activate RNA Polymerase II by aiding formation of a stable transcription pre-initiation complex required for its activation.

  4. ASH2L enhances ERalpha (zeige ESR1 Antikörper) expression as a coactivator of GATA3 (zeige GATA3 Antikörper) in breast cancers

  5. Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5 (zeige RBBP5 Antikörper)/Ash2L heterodimer.

  6. Data indicate that MLL1 methylates Ash2L in the absence of histone H3 (zeige HIST3H3 Antikörper), but only when assembled within a complex with WDR5 (zeige WDR5 Antikörper) and RbBP5 (zeige RBBP5 Antikörper).

  7. H2B dependent regulation of MLL (zeige MLL Antikörper) family histone methylatransferases depends on the N-terminal WH motif of ASH2L.

  8. crystal structure of the C-terminal SPRY domain of human Ash2L

  9. The structure shows that Ash2L contains an atypical PHD (zeige PDC Antikörper) finger that does not have histone tail-binding activity.

  10. ASH2L binds DNA using a forkhead-like helix-wing-helix (HWH) domain.

Mouse (Murine) Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) Interaktionspartner

  1. We discuss the implications of these results to understand the role of ASH2L and Xist repeat E for histone modifications and escape gene regulation during random X-chromosome inactivation.

  2. ASH2L enhances ERalpha (zeige ESR1 Antikörper) expression as a coactivator of GATA3 (zeige GATA3 Antikörper) in breast cancers

  3. Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells

  4. Tbx1 (zeige TBX1 Antikörper) and Ash2l have overlapping mRNA and protein expression patterns during development.

  5. Several candidate targets of complexes containing Ap2delta and Ash2l were identified that can be used to further elucidate their roles during development and showed that Fgfr3 (zeige FGFR3 Antikörper) is a novel direct target of these complexes.

  6. Ap2delta associates with ASH2L and MLL2 (ALR (zeige MLL2 Antikörper)), forming a complex that methylates lysine 4 of histone H3 (zeige HIST3H3 Antikörper).

ASH2L Antigen-Profil

Protein Überblick

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis (By similarity).

Genbezeichner und Symbole assoziert mit ASH2L

  • ASH2 like histone lysine methyltransferase complex subunit (ASH2L) Antikörper
  • ash2 (absent, small, or homeotic)-like (Drosophila) (Ash2l) Antikörper
  • ash2 (absent, small, or homeotic)-like (Drosophila) (ash2l) Antikörper
  • ash2 (absent, small, or homeotic)-like L homeolog (ash2l.L) Antikörper
  • ASH2 like histone lysine methyltransferase complex subunit (Ash2l) Antikörper
  • ASH2 Antikörper
  • ash2-like Antikörper
  • ASH2L Antikörper
  • ASH2L1 Antikörper
  • ASH2L2 Antikörper
  • Bre2 Antikörper
  • fb34c06 Antikörper
  • fe38b04 Antikörper
  • fi20h02 Antikörper
  • wu:fb34c06 Antikörper
  • wu:fe38b04 Antikörper
  • wu:fi20h02 Antikörper
  • zgc:171444 Antikörper

Bezeichner auf Proteinebene für ASH2L

ASH2-like protein , set1/Ash2 histone methyltransferase complex subunit ASH2 , ash2-like

GENE ID SPEZIES
9070 Homo sapiens
23808 Mus musculus
426774 Gallus gallus
558193 Danio rerio
699382 Macaca mulatta
100127317 Xenopus laevis
290829 Rattus norvegicus
475589 Canis lupus familiaris
100138350 Bos taurus
100732899 Cavia porcellus
100059465 Equus caballus
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