anti-Amyloid P Component, serum (APCS) Antikörper

The protein encoded by APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. Zusätzlich bieten wir Ihnen Amyloid P Component, serum Kits (48) und Amyloid P Component, serum Proteine (34) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
APCS 325 P02743
APCS 29339 P23680
APCS 20219 P12246
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Top anti-Amyloid P Component, serum Antikörper auf antikoerper-online.de

Showing 10 out of 134 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-APCS Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB APCS Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow). APCS antibody (C-term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB APCS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. APCS Antibody (C-term) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the APCS antibody detected the APCS protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Ratte Kaninchen Unkonjugiert IHC (p), WB Anti-Serum Amyloid P Picoband antibody,  All lanes: Anti- Serum Amyloid P at 0.5ug/ml WB: Recombinant Rat Serum Amyloid P Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD Anti-Serum Amyloid P Picoband antibody,  IHC(P): Rat Liver Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Maus Kaninchen Unkonjugiert IHC (p), ELISA, WB Anti-Serum Amyloid P Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-Serum Amyloid P Picoband antibody,  All lanes: Anti-Serum Amyloid P at 0.5ug/ml WB: Recombinant Mouse Serum Amyloid P Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Maus Unkonjugiert EIA, IHC (p), IP, WB 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot analysis of human and mouse serum using 1 µg/mL Rabbit Anti-Serum Amyloid P Polyclonal Antibody (ABIN398517) Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody (ABIN398323, 1: 20,000) The signal was developed with LumiSensorTM HRP Substrate Kit (ABIN769939) 40 μg Anmelden zum Anzeigen 6 bis 8 Tage
187,10 €
Details
Human Maus Unkonjugiert WB APCS antibody  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow). 0.1 mL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert EIA, RIA   0.2 mg Anmelden zum Anzeigen 7 bis 9 Tage
561,00 €
Details
Meerschweinchen Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details

APCS Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Amyloid P Component, serum Antikörper

  1. Human Polyclonal APCS Primary Antibody für EIA, IHC (p) - ABIN954752 : Song, Cai, Guo, Tsukamoto, Yutani, Li: Accumulation and expression of serum amyloid P component in human atherosclerotic lesions. in Atherosclerosis 2010 (PubMed)
    Zeige alle 5 Referenzen für 954752

  2. Mouse (Murine) Polyclonal APCS Primary Antibody für ELISA, WB - ABIN1573937 : Maher, Dargusch, Ehren, Okada, Sharma, Schubert: Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes. in PLoS ONE 2011 (PubMed)
    Zeige alle 3 Referenzen für 1573937

  3. Guinea Pig Polyclonal APCS Primary Antibody für IHC, WB - ABIN2777091 : Veerhuis, Boshuizen, Morbin, Mazzoleni, Hoozemans, Langedijk, Tagliavini, Langeveld, Eikelenboom: Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q. in Neurobiology of disease 2005 (PubMed)
    Zeige alle 2 Referenzen für 2777091

  4. Human Monoclonal APCS Primary Antibody für WB - ABIN658915 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)

Weitere Antikörper gegen Amyloid P Component, serum Interaktionspartner

Human Amyloid P Component, serum (APCS) Interaktionspartner

  1. The findings suggest that the F57I mutation affects the aggregation process of lysozyme (zeige LYZ Antikörper) resulting in the formation of cytotoxic species and that SAP is able to prevent cell death in the F57I flies by preventing accumulation of toxic F57I structures.

  2. Data suggest that SAP (serum amyloid P-component) interacts with at least 33 proteins/ligands in plasma containing physiological calcium levels; these ligands can be categorized to include apolipoproteins, complement system proteins, coagulation proteins, and components that regulate proteolysis.

  3. Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects.

  4. SNPs in APCS were associated with late age at onset in familial amyloid polyneuropathy.

  5. Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN (zeige CD209 Antikörper) to regulate the innate immune system differently from C-reactive protein (CRP (zeige CRP Antikörper)), and that DC-SIGN (zeige CD209 Antikörper) is a target for antifibrotics.

  6. Here, it is reported that X-ray analysis of the SAP complex with CPHPC and cadmium ions provides higher resolution detail of the interaction than is observed with calcium ions.

  7. Compared to wildtype C57BL/6 mice, we find that in Apcs-/- "SAP knock-out" mice, bleomycin induces a more persistent inflammatory response and increased fibrosis.

  8. The effects of SAP and Xiapex (Collagenase Clostridium histolyticum) on fibrocytes derived from Dupuytren's disease, was evaluated.

  9. plasma protein serum amyloid P binds to FcgammaRI (zeige FCGR1A Antikörper) on monocytes to inhibit fibrocyte differentiation, and binds to FcgammaRIIa on neutrophils to reduce neutrophil adhesion.

  10. In the late phase post-myocardial infarct there is a coordinated decrease in immune response-inflammation proteins, except for SAP which showed an increase related to the specific activation of the classical complement pathway.

Mouse (Murine) Amyloid P Component, serum (APCS) Interaktionspartner

  1. SAP deficiency mitigated foam cell formation and atherosclerotic development in apoE (zeige APOE Antikörper)(-/-) mice, due to reduction in macrophages recruitment, polarization and pro-inflammatory cytokines

  2. Data suggest that serum amyloid P (SAP) activates CD209 DC-SIGN (zeige CD209 Antikörper) to regulate the innate immune system differently from C-reactive protein (CRP (zeige CRP Antikörper)), and that DC-SIGN (zeige CD209 Antikörper) is a target for antifibrotics.

  3. observations suggest that serum amyloid P, at least in part, uses FcgammaRI (zeige FCGR1A Antikörper) and FcRgamma (zeige FCER1G Antikörper) to inhibit fibrocyte differentiation

  4. Bglu3 is confirmed to be a locus affecting diabetes susceptibility, and Apcs is a probable candidate gene.

  5. binding of SAP to ALD (zeige ABCD1 Antikörper)-DNA could switch macrophage phenotypic polarization from proinflammatory M2b to anti-inflammatory M2a via PI3K/Akt (zeige AKT1 Antikörper)-ERK (zeige EPHB2 Antikörper) signaling activation, thus exerting protective and therapeutic interventions on murine lupus nephritis

  6. SAP has an effect on macrophages in fibrotic lung disease

  7. sFRP4 (zeige SFRP4 Antikörper) negatively regulates bone formation without disrupting phosphorus homeostasis.

  8. Binding of mouse and human SAP to immobilized influenza virus was compared. Mouse SAP bound much less avidly than human SAP.mouse SAP apparently plays no significant role during infection of mice with influenza virus.

  9. Targeted pharmacological depletion of serum amyloid P component for treatment of amyloidosis

  10. during murine tuberculosis (TB) SAP levels were increased; purified mouse SAP inhibited the intra-alveolar macrophage M. tuberculosis growth, in vitro; SAP may thus contribute both to the pathogenesis and pulmonary innate immunity in TB

Amyloid P Component, serum (APCS) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Genbezeichner und Symbole assoziert mit APCS

  • amyloid P component, serum (APCS) Antikörper
  • amyloid P component, serum (Apcs) Antikörper
  • C-reactive protein, pentraxin-related (CRP) Antikörper
  • serum amyloid P-component (Apcs) Antikörper
  • serum amyloid P-component-like (LOC100352593) Antikörper
  • APCS Antikörper
  • PTX2 Antikörper
  • Sap Antikörper

Bezeichner auf Proteinebene für APCS

amyloid P component, serum , pentraxin , C-reactive protein , amyloid P component serum , 9.5S alpha-1-glycoprotein , pentaxin-related , serum amyloid P-component , serum amyloid P component , Serum amyloid P-component , SAP , APCS amyloid P-component serum protein

GENE ID SPEZIES
457427 Pan troglodytes
100126558 Meleagris gallopavo
325 Homo sapiens
396921 Sus scrofa
29339 Rattus norvegicus
100726823 Cavia porcellus
514488 Bos taurus
776376 Gallus gallus
20219 Mus musculus
100352593 Oryctolagus cuniculus
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