Aflatoxin Beta1 Aldehyde Reductase Proteine (AKR7A2)

The protein encoded by AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. Zusätzlich bieten wir Ihnen AKR7A2 Antikörper (68) und AKR7A2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AKR7A2 8574 O43488
AKR7A2 171445 Q8CG45
AKR7A2 110198 Q8CG76
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Showing 9 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
483,07 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
387,62 €
Details
HOST_Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.861,74 €
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
3.855,24 €
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 7 bis 8 Tage
460,80 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
455,10 €
Details

AKR7A2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Am meisten referenzierte AKR7A2 Proteine

  1. Human AKR7A2 Protein expressed in Escherichia coli (E. coli) - ABIN667763 : Bodreddigari, Jones, Egner, Groopman, Sutter, Roebuck, Guengerich, Kensler, Sutter: Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3. in Chemical research in toxicology 2008 (PubMed)
    Zeige alle 2 Referenzen für 667763

  2. Human AKR7A2 Protein expressed in Wheat germ - ABIN1344772 : Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism. in Xenobiotica; the fate of foreign compounds in biological systems 2015 (PubMed)

Weitere Proteine zu Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) Interaktionspartnern

Human Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) Interaktionspartner

  1. AKR7A2 physically interacts with CYGB (zeige CYGB Proteine).

  2. AKR7A2 contributes to protection against MG-induced toxicity.

  3. structure and tissue-related expression of AFAR genes on chromosome 1

  4. The human aldo-keto reductase AKR7A2 has been proposed previously to catalyze the NADPH (zeige NQO1 Proteine)-dependent reduction of succinic semialdehyde (SSA (zeige TRIM21 Proteine)) to gamma-Hydroxybutyrate in human brain

  5. The human AFAR gene family maps to a genomic region in 1p36 of frequent hemizygous deletions in various human cancers.

  6. Aflatoxin B(1) aldehyde reductase (zeige ADH1B Proteine) (AKR7A2) was confirmed to be only highly expressed in pancreatic cancer, not in normal adjacent pancreas and benign tumors.

Mouse (Murine) Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) Interaktionspartner

  1. These findings indicate the importance of AKR7A5 in protecting cells from the damaging effects of oxidative stress, and that this cytoprotective function is carried out through multiple pathways.

  2. AKR7A5 has selective substrate specificity towards naphthoquinone derivatives, suggesting that the aldo-keto reductase could play an important role in metabolism of certain naphthoquinone derivatives.

  3. structure and tissue-related expression of AFAR genes

AKR7A2 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.

Genbezeichner und Symbole assoziert mit AKR7A2

  • aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2)
  • aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (Akr7a2)
  • aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) (Akr7a5)
  • 0610025K21Rik Protein
  • Afar Protein
  • Afar1 Protein
  • AFB1-AR1 Protein
  • Aiar Protein
  • AKR7 Protein
  • Akr7a2 Protein

Bezeichner auf Proteinebene für AKR7A2

AFB1 aldehyde reductase 1 , AFB1-AR 1 , SSA reductase , aflatoxin B1 aldehyde reductase member 2 , aflatoxin beta1 aldehyde reductase , aldoketoreductase 7 , succinic semialdehyde reductase , rAFAR2

GENE ID SPEZIES
8574 Homo sapiens
171445 Rattus norvegicus
110198 Mus musculus
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