(Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011].
Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).
Kassner, Huse, Martin, Gödtel-Armbrust, Metzger, Meineke, Brockmöller, Klein, Zanger, Maser, Wojnowski: "Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 10, pp. 2113-20, (2008) (PubMed).
Aliase für AKR1A1 Proteine
aldo-keto reductase family 1, member A1a (aldehyde reductase) (akr1a1a) Proteine aldo-keto reductase family 1, member A1 (aldehyde reductase) (akr1a1) Proteine aldo-keto reductase family 1 member A1 (AKR1A1) Proteine aldo-keto reductase family 1, member A1b (aldehyde reductase) (akr1a1b) Proteine aldehyde reductase (AKR1A1) Proteine aldo-keto reductase family 1 member A1 (Akr1a1) Proteine aldo-keto reductase family 1, member A1 (aldehyde reductase) (Akr1a1) Proteine aldo-keto reductase family 1, member A1 (aldehyde reductase) L homeolog (akr1a1.L) Proteine 2610201A18Rik Proteine akr1a1 Proteine AKR1A1 Proteine Akr1a4 Proteine aldr1 Proteine ALDR1 Proteine alr Proteine ALR Proteine Alr Proteine ALR1 Proteine arm Proteine ARM Proteine dd3 Proteine DD3 Proteine zgc:100940 Proteine zgc:110225 Proteine