anti-SETD2 (SETD2) Antikörper

Bezeichnung:: anti-SET Domain Containing 2 Antikörper (SETD2)

Auf www.antikoerper-online.de finden Sie aktuell 76 SET Domain Containing 2 (SETD2) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 83 SETD2 Produkte verfügbar.

Synonyme:: HBP231, HIF-1, HIP-1, HYPB, Kif9, KMT3A, p231HBP, SET2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	SETD2	316013
	SETD2	29072	Q9BYW2
	SETD2
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anti-Rat (Rattus) SETD2 Antikörper:

anti-Human SETD2 Antikörper:

anti-Mouse (Murine) SETD2 Antikörper:

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Verknüpfte Pathways mit anti-SETD2 Antikörper

Tube Formation

Am meisten referenzierte anti-SETD2 Antikörper

Mouse (Murine) Polyclonal SETD2 Primary Antibody für ELISA, WB - ABIN262286 : Sun, Wei, Wu, Hu, Wang, Wang, Zhang, Chen, Huang, Chen: Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. in The Journal of biological chemistry 2005 (PubMed)
Human Polyclonal SETD2 Primary Antibody für ICC, IF - ABIN4320758 : Kanu, Grönroos, Martinez, Burrell, Yi Goh, Bartkova, Maya-Mendoza, Mistrík, Rowan, Patel, Rabinowitz, East, Wilson, Santos, McGranahan, Gulati, Gerlinger, Birkbak, Joshi, Alexandrov, Stratton, Powles et al.: SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ... in Oncogene 2015 (PubMed)
Cow (Bovine) Polyclonal SETD2 Primary Antibody für IHC, WB - ABIN2783051 : Barrand, Andersen, Collas: Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes. in Biochemical and biophysical research communications 2010 (PubMed)

Weitere Antikörper gegen SETD2 Interaktionspartner

Human SET Domain Containing 2 (SETD2) Interaktionspartner

The fusion transcript codes for a protein in which the last 114 amino acids of SETD2, i.e., the entire Set2 Rpb1 (zeige POLR2A Antikörper) interacting (SRI (zeige SRI Antikörper)) domain of SETD2, are replaced by 30 amino acids encoded by the NF1 (zeige NF1 Antikörper) sequence.
Our work defines SETD2 as a tumor suppressor gene in Hepatosplenic T-cell lymphoma (HSTL)and implicates genes including INO80 and PIK3CD in the disease
The findings, specifically frequent mutations of STAT5B (zeige STAT5B Antikörper), PIK3CD, and the histone methyltransferase SETD2, may help guide translational efforts to target hepatosplenic T-cell lymphoma
SETD2 Mutation is associated with Clear Cell Renal Cell Carcinomas.
SETD2 downregulation affects the alternative splicing of a subset of genes implicated in intestinal tumorigenesis
SETD2 aberration as a recurrent, early loss-of-function event in CLL pathobiology linked to aggressive disease
Setd2 as a potent tumor suppressor in lung adenocarcinoma.
This study reports a new role for SETD2 in promoting IFNalpha-induced antiviral immune response by directly methylating STAT1 (zeige STAT1 Antikörper) on lysine 525 and catalyzing H3K36me3 on the promoters of some IFN-stimulated genes (ISGs such as ISG15 (zeige ISG15 Antikörper)) to activate gene transcription. Thus, SETD2 enhances host antiviral immunity by strengthening IFNalpha signaling both post-translationally and epigenetically.
SETD2 is a novel GIST tumour suppressor gene associated with disease progression.
Results identified new role for SETD2 in the methylation of K40 of alpha-tubulin (zeige TUBA4A Antikörper). Loss of SETD2 abolishes methylation of K40 of alpha-tubulin (zeige TUBA4A Antikörper) and results in a dysfunctional mitotic spindle and abnormalities in cytokinesis. Thus, SETD2 links chromatin and cytoskeleton homeostasis through its methyltransferase activity.

SETD2 Antigen-Profil

Beschreibung des Gens

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Alternative names and synonyms associated with SETD2

SET domain containing 2 (Setd2) Antikörper
SET domain containing 2 (SETD2) Antikörper

HBP231 Antikörper
HIF-1 Antikörper
HIP-1 Antikörper
HYPB Antikörper
Kif9 Antikörper
KMT3A Antikörper
p231HBP Antikörper
SET2 Antikörper

Bezeichner auf Proteinebene für SETD2

histone-lysine N-methyltransferase SETD2 , kinesin family member 9 , huntingtin interacting protein 1 , huntingtin yeast partner B , huntingtin-interacting protein B , lysine N-methyltransferase 3A

GENE ID	SPEZIES
316013	Rattus norvegicus
476643	Canis lupus familiaris
29072	Homo sapiens

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Show all anti-SET Domain Containing 2 (SETD2) Antikörper with Pubmed References

Human SET Domain Containing 2 (SETD2) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with SETD2

Bezeichner auf Proteinebene für SETD2