SETD2 Produkte
(SET Domain Containing 2 (SETD2))
Kategorien
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008].
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Ausgewählte SETD2 Kategorien
SETD2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene SETD2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
- (10)
Kat. Nr.
ABIN1682666
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN7193416
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN238587
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SETD2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6205033
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SETD2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN2669625
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus
Validierungen
- (1)
Kat. Nr.
ABIN2669663
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SETD2 Produkten
: "HnRNPL inhibits the osteogenic differentiation of PDLCs stimulated by SrCl2 through repressing Setd2." in: Journal of cellular and molecular medicine, Vol. 23, Issue 4, pp. 2667-2677, (2020) (PubMed).: "H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation." in: The Journal of biological chemistry, Vol. 293, Issue 20, pp. 7811-7823, (2019) (PubMed).
: "Setd2 is associated with strontium-induced bone regeneration." in: Acta biomaterialia, Vol. 53, pp. 495-505, (2018) (PubMed).
: "Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity." in: Cell, Vol. 170, Issue 3, pp. 492-506.e14, (2017) (PubMed).
: "SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing." in: Nucleic acids research, Vol. 45, Issue 1, pp. 92-105, (2017) (PubMed).
: "Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 4, pp. 697-707, (2017) (PubMed).
: "SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ..." in: Oncogene, Vol. 34, Issue 46, pp. 5699-708, (2015) (PubMed).
: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).
: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
: "Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35261-71, (2005) (PubMed).
Synonyme und alternative Namen zu SETD2
SET domain containing 2 (Setd2), SET domain containing 2 (SETD2), HBP231, HIF-1, HIP-1, HYPB, Kif9, KMT3A, p231HBP, SET2Bezeichner auf Proteinebene für SETD2
- histone-lysine N-methyltransferase SETD2
- kinesin family member 9
- huntingtin interacting protein 1
- huntingtin yeast partner B
- huntingtin-interacting protein B
- lysine N-methyltransferase 3A
Haben Sie etwas anderes gesucht?
- SETD1B
- SETD1A
- SETBP1
- SET7/9
- SET7
- SET/TAF-I
- SET Domain, Bifurcated 1
- SET Domain Containing (Lysine Methyltransferase) 8
- SET Binding Factor 2
- SET and MYND Domain Containing 2a
- SET and MYND Domain Containing 1
- Sestrin 2
- SESTD1
- SESN3
- SESN1
- Seryl-tRNA Synthetase
- serum/glucocorticoid Regulated Kinase 2
- serum/glucocorticoid Regulated Kinase 1
- Serum Amyloid A3 Pseudogene
- SERTM1
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