SETD2 Antikörper (N-Term)

Produktnummer ABIN2783051

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SETD2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Hund und Pferd.Es wurde in 1 Publikation zitiert.

Kurzübersicht für SETD2 Antikörper (N-Term) (ABIN2783051)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reaktivität: Human, Ratte, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SETD2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SETD2 Antibody - N-terminal region

Sequenz: SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD

Kreuzreaktivität: Hund, Human, Ratte (Rattus)

Homologie: Dog: 86%, Horse: 86%, Human: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47617-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SETD2 Antikörper (ABIN2783051)

Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).

Details zu SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Andere Bezeichnung: SETD2

Hintergrund:

Background Information: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.

Gene Name: SET domain containing 2

Alternative Symbols: LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

Protein Name: Histone-lysine N-methyltransferase SETD2

Molekulargewicht: 97kDa

Gen-ID: 29072

UniProt: Q9BYW2

Pathways: Tube Formation