SRPK2 Produkte
(SFRS Protein Kinase 2 (SRPK2))
Kategorien
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up- regulation. Plays an essential role in splicesomal B complex formation via the phosphorylation of DDX23/PRP28.
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Ausgewählte SRPK2 Kategorien
SRPK2 Antikörper
High quality antibodies with extensive validation data.
SRPK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SRPK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN968376
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7170677
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN391795
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene SRPK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570616
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5570614
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321346
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SRPK2 Produkten
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
: "SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 737-50, (1998) (PubMed).
Synonyme und alternative Namen zu SRPK2
SRSF protein kinase 2 (SRPK2), serine/arginine-rich protein specific kinase 2 (Srpk2), SRSF protein kinase 2 (Srpk2), SRSF protein kinase 2 (srpk2), SRSF protein kinase 2 L homeolog (srpk2.L), AW226533, AW492537, AW547358, mSRPK2, SFRSK2, sfrsk2, srpk2, srpk2-b, srpk2b, Wbp6Bezeichner auf Proteinebene für SRPK2
- SFRS protein kinase 2
- SR protein kinase 2
- SR-protein-specific kinase 2
- serine kinase SRPK2
- serine/arginine-rich protein-specific kinase 2
- serine/arginine-rich splicing factor kinase 2
- serine/threonine-protein kinase SRPK2
- SRSF protein kinase 2
- WW domain binding protein 6
- serine/arginine-rich protein specific kinase 2
- serine/threonine-protein kinase SRPK2-like
- SFRS protein kinase 2b
- SRSF protein kinase 2 L homeolog
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