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SRF Produkte

(Serum Response Factor (SRF))
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways\; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

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Ausgewählte SRF Kategorien

SRF Antikörper

High quality antibodies with extensive validation data.

SRF ELISA Kits

Reliable ELISA kits for a wide range of species.

SRF Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SRF Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN686017
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (4)
Kat. Nr. ABIN520472
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6255577
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SRF ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970415
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380137
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5691922
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene SRF Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321311
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3077546
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3130359
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SRF Produkten

Park, Lee, Yeom, Heo, Lim: "Neuroprotective effect of Ruminococcus albus on oxidatively stressed SH-SY5Y cells and animals." in: Scientific reports, Vol. 7, Issue 1, pp. 14520, (2018) (PubMed).

Haikala, Marques, Turunen, Klefström: "Myc requires RhoA/SRF to reprogram glutamine metabolism." in: Small GTPases, pp. 1-9, (2016) (PubMed).

Werfel, Jungmann, Lehmann, Ksienzyk, Bekeredjian, Kaya, Leuchs, Nordheim, Backs, Engelhardt, Katus, Müller: "Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase." in: Cardiovascular research, Vol. 104, Issue 1, pp. 15-23, (2014) (PubMed).

Stern, Haverkamp, Sinske, Tedeschi, Naumann, Di Giovanni, Kochanek, Nordheim, Knöll: "The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 48, pp. 18836-48, (2013) (PubMed).

Härmä, Knuuttila, Virtanen, Mirtti, Kohonen, Kovanen, Happonen, Kaewphan, Ahonen, Kallioniemi, Grafström, Lötjönen, Nees: "Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models." in: Oncogene, Vol. 31, Issue 16, pp. 2075-89, (2012) (PubMed).

Koegel, von Tobel, Schäfer, Alberti, Kremmer, Mauch, Hohl, Wang, Beer, Bloch, Nordheim, Werner: "Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice." in: The Journal of clinical investigation, Vol. 119, Issue 4, pp. 899-910, (2009) (PubMed).

Petit, Lindskog, Larsson, Wasteson, Athley, Breuer, Angstenberger, Hertfelder, Mattsson, Nordheim, Nelander, Lindahl: "Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin." in: Circulation research, Vol. 103, Issue 1, pp. 61-9, (2008) (PubMed).

Davis, Gupta, Pogwizd, Bacha, Jeevanandam, Gupta: "Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts." in: American journal of physiology. Heart and circulatory physiology, Vol. 282, Issue 4, pp. H1521-33, (2002) (PubMed).

Synonyme und alternative Namen zu SRF

serum response factor (Srf), serum response factor (SRF), serum response factor L homeolog (srf.L), serum response factor a (srfa), AW049942, AW240594, MCM1, RGD1559787, srf, srf-A, srf1, SRFX, XSRF

Bezeichner auf Proteinebene für SRF

  • serum response factor
  • DreSrf1
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