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SRGN Produkte

(serglycin (SRGN))
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010].

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Ausgewählte SRGN Kategorien

SRGN Antikörper

High quality antibodies with extensive validation data.

SRGN ELISA Kits

Reliable ELISA kits for a wide range of species.

SRGN Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SRGN Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN519156
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7435199
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7436939
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SRGN ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959372
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959373
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730770
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SRGN Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321323
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321324
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3132951
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SRGN Produkten

Ma, Gu, Li, Zhang, Cui, Qu, Wang, Humphry, Durkan, Qiu, Wang: "SRGN, a new identified shear-stress-responsive gene in endothelial cells." in: Molecular and cellular biochemistry, Vol. 474, Issue 1-2, pp. 15-26, (2020) (PubMed).

Zhang, Deng, Zheng, Jia, Xiong, Luo, Qiu, Qiu, Yin, Lu, Liu, Gu, He: "SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer." in: Oncogenesis, Vol. 6, Issue 7, pp. e360, (2017) (PubMed).

Reine, Vuong, Rutkovskiy, Meen, Vaage, Jenssen, Kolset: "Serglycin in Quiescent and Proliferating Primary Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145584, (2015) (PubMed).

Gasimli, Hickey, Yang, Li, dela Rosa, Nairn, Kulik, Dordick, Moremen, Dalton, Linhardt: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." in: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).

Reine, Vuong, Jenssen, Kolset: "Serglycin secretion is part of the inflammatory response in activated primary human endothelial cells in vitro." in: Biochimica et biophysica acta, Vol. 1840, Issue 8, pp. 2498-505, (2014) (PubMed).

Purushothaman, Toole: "Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization." in: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5499-509, (2014) (PubMed).

Chang, Chan, Braun, Green, OBrien, Chait, Day, Wight: "Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix." in: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 14122-35, (2012) (PubMed).

Li, Ong, Cao, Xiang, Shao, Ooi, Peng, Lu, Zhang, Petillo, Qin, Bao, Zheng, Chia, Iyer, Kang, Zeng, Soo, Trent, Teh, Qian: "Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis." in: Cancer research, Vol. 71, Issue 8, pp. 3162-72, (2011) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Synonyme und alternative Namen zu SRGN

serglycin (SRGN), serglycin (Srgn), Pgsg, PPG, PRG, Prg, PRG1, Prg1, Sgc

Bezeichner auf Proteinebene für SRGN

  • hematopoetic proteoglycan core peptide
  • hematopoetic proteoglycan core protein
  • hematopoietic proteoglycan core protein
  • p.PG
  • platelet proteoglycan core protein
  • proteoglycan 1, secretory granule
  • proteoglycan protein core for mast cell secretory granule
  • secretory granule proteoglycan core peptide
  • secretory granule proteoglycan core protein
  • serglycin proteoglycan
  • gp600
  • mastocytoma proteoglycan core protein
  • proteoglycan, secretory granule
  • PG19 core protein
  • chondroitin sulfate proteoglycan core protein
  • cytolytic granule proteoglycan core protein
  • proteoglycan 10K core protein
  • proteoglycan peptide core protein
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