SRGN Protein (His-Myc tag)

Produktnummer ABIN7317217

Dieses Recombinant SRGN-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für SRGN Protein (His-Myc tag) (ABIN7317217)

Target: SRGN (serglycin (SRGN))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 90 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses SRGN Protein ist gelabelt mit His-Myc tag.

Verwendungszweck: Recombinant Human Serglycin/SRGN Protein (His&Myc Tag)

Sequenz: Met 1-Leu158

Produktmerkmale: A DNA sequence encoding the human SRGN (Met1-Leu158) was fused with the C-terminal polyhistidine-tagged myc at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: SRGN (serglycin (SRGN))

Andere Bezeichnung: Serglycin/SRGN

Hintergrund: PPG,PRG,PRG1,SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

Molekulargewicht:

Calculated MW: 17.3 kDa

Observed MW: 27 kDa

Gen-ID: 5552

UniProt: P10124

Pathways: Maintenance of Protein Location