SRRT Produkte
(Serrate RNA Effector Molecule Homolog (SRRT))
Kategorien
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA)\; however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
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Ausgewählte SRRT Kategorien
SRRT Antikörper
High quality antibodies with extensive validation data.
SRRT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SRRT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN526827
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN2613482
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7169355
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SRRT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345737
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2714949
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Chinese Hamster
Source
Yeast
Validierungen
Kat. Nr.
ABIN1635251
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SRRT Produkten
: "Knockdown of arsenic resistance protein 2 inhibits human glioblastoma cell proliferation through the MAPK/ERK pathway." in: Oncology reports, Vol. 40, Issue 6, pp. 3313-3322, (2019) (PubMed).: "Mutagenesis of ARS2 Domains To Assess Possible Roles in Cell Cycle Progression and MicroRNA and Replication-Dependent Histone mRNA Biogenesis." in: Molecular and cellular biology, Vol. 35, Issue 21, pp. 3753-67, (2015) (PubMed).
: "Ars2 promotes proper replication-dependent histone mRNA 3' end formation." in: Molecular cell, Vol. 45, Issue 1, pp. 87-98, (2012) (PubMed).
Synonyme und alternative Namen zu SRRT
Arsenic resistance protein 2 (Ars2), serrate, RNA effector molecule S homeolog (srrt.S), serrate, RNA effector molecule (SRRT), serrate RNA effector molecule homolog (Arabidopsis) (Srrt), serrate, RNA effector molecule (Srrt), serrate RNA effector molecule homolog (Arabidopsis) (srrt), 2810019G02Rik, anon-WO0118547.166, ars2, ARS2, Ars2, ars2-A, ASR2, Asr2, ASR2A, ASR2B, ASR2C, ASR2D, CG7843, CHUNP6881, Dmel\\CG7843, MGC92060, serrate, zgc:92060Bezeichner auf Proteinebene für SRRT
- Ars2-PA
- Ars2-PC
- Ars2-PD
- Ars2-PE
- Ars2-PF
- Ars2-PG
- CG7843-PA
- CG7843-PC
- CG7843-PD
- CG7843-PE
- CG7843-PF
- CG7843-PG
- Arsenite-resistance protein 2-A
- serrate RNA effector molecule homolog A
- arsenate resistance protein 2
- arsenate resistance protein ARS2
- arsenite resistance protein
- arsenite-resistance protein 2
- serrate RNA effector molecule homolog
- Arsenite-resistance protein 2
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