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anti-Human GLUT1 Antikörper:
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Human Polyclonal GLUT1 Primary Antibody für ELISA, ICC - ABIN152817
Minamishima, Moslehi, Bardeesy, Cullen, Bronson, Kaelin: Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. in Blood 2008
Show all 18 Pubmed References
Human Polyclonal GLUT1 Primary Antibody für ChIP, FACS - ABIN258123
Hergovich, Lisztwan, Thoma, Wirbelauer, Barry, Krek: Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3. in Molecular and cellular biology 2006
Show all 14 Pubmed References
Human Monoclonal GLUT1 Primary Antibody für CyTOF, FACS - ABIN4899145
Jain, Manuel, Khan, Ahuja, Quann, Wigdahl: DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells. in Journal of virology 2009
Show all 9 Pubmed References
Human Polyclonal GLUT1 Primary Antibody für IHC (p), WB - ABIN4886725
Xu, Bao, Zhou, Fan: Effect on the expression of MMP-2, MT-MMP in laryngeal carcinoma Hep-2 cell line by antisense glucose transporter-1. in Archives of medical research 2012
Show all 6 Pubmed References
Human Monoclonal GLUT1 Primary Antibody für FACS - ABIN4895661
Patsoukis, Bardhan, Chatterjee, Sari, Liu, Bell, Karoly, Freeman, Petkova, Seth, Li, Boussiotis: PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. in Nature communications 2015
Show all 5 Pubmed References
Human Monoclonal GLUT1 Primary Antibody für FACS - ABIN4895663
Prost, Relouzat, Spentchian, Ouzegdouh, Saliba, Massonnet, Beressi, Verhoeyen, Raggueneau, Maneglier, Castaigne, Chomienne, Chrétien, Rousselot, Leboulch: Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists. in Nature 2015
Show all 3 Pubmed References
Human Polyclonal GLUT1 Primary Antibody für FACS, ICC - ABIN5076961
Rodríguez-Espinosa, Rojas-Espinosa, Moreno-Altamirano, López-Villegas, Sánchez-García: Metabolic requirements for neutrophil extracellular traps formation. in Immunology 2015
Show all 2 Pubmed References
Human Monoclonal GLUT1 Primary Antibody für FACS - ABIN4895662
Feldhoff, Rueda, Moreno-Fernandez, Sauer, Jackson, Chougnet, Rupp: IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+T cells. in Scientific reports 2017
Human Monoclonal GLUT1 Primary Antibody für FACS - ABIN4895659
Palmer, Ostrowski, Gouillou, Tsai, Yu, Zhou, Henstridge, Maisa, Hearps, Lewin, Landay, Jaworowski, McCune, Crowe: Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. in AIDS 2014
Human Polyclonal GLUT1 Primary Antibody für IHC, ELISA - ABIN1582249
Wang, Li, Gao, Lu, Zhang, Ma, Ye, Zhang: Cardiotrophin-1 (CTF1) ameliorates glucose-uptake defects and improves memory and learning deficits in a transgenic mouse model of Alzheimer's disease. in Pharmacology, biochemistry, and behavior 2013
Data suggest that plasma glycation with erythrocyte membrane modification is associated with oxidative stress, GLUT1 expression, and erythrocyte fragility in patients with type 2 diabetes; such glycation may further contribute to progression of diabetic vascular complications.
Antibody therapy targeted at AFP-producing tumor cells showed an inhibitory effect on the PI3K/AKT pathway via the liberation, restoration and functional stabilization of PTEN. PTEN simultaneously induced both P53 activation and intracellular translocation of GLUT1, since these are closely associated with PTEN.
FOXM1 (zeige FOXM1 Antikörper) bound directly to the GLUT1 and HK2 (zeige HK2 Antikörper) promoter regions and regulated the promoter activities and the expression of the genes at the transcriptional level. This reveals a novel mechanism by which glucose metabolism is regulated by FOXM1 (zeige FOXM1 Antikörper).
Whereas, Glut1-mediated glucose uptake also requires mTORC2 (zeige CRTC2 Antikörper) phosphorylation of the hydrophobic domain, demonstrating both phosphorylation-dependent and independent roles of the hydrophobic domain in regulating glucose uptake.
The levels of GLUT1 and GLUT3 (zeige SLC2A3 Antikörper), the major brain glucose transporters, are decreased, especially in the cerebral cortex in patient with Alzheimer disease.
this study shows that PTEN dephosphorylates AKT (zeige AKT1 Antikörper) to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells
High levels of GLUT1 are associated with Lung Adenocarcinoma.
Glucose transporter type 1 deficiency syndrome is the result of impaired glucose transport into the brain. Patients with glucose transporter type 1 syndrome may present with infantile seizures, developmental delay, acquired microcephaly, spasticity and ataxia.
The results demonstrated the high frequency of C allele of SLC2A1 HaeIII in Kurdish patients with diabetic nephropathy. It was also found that this polymorphism is a significant risk factor for diabetic nephropathy. The effect of this polymorphism on clinical and laboratory characteristics of diabetic nephropathy patients was significant.
Expression of GLUT1 is stimulated by hyperglycemia and low oxygen supply, and this overexpression was associated with increased activity of GLUT1 in the cell membrane that contributes to the impairment of the RPE (zeige RPE Antikörper) secretory function of PEDF (zeige SERPINF1 Antikörper).
Immunoreactivity of vGluT1 in continuous theta-burst stimulation (iTBS; cTBS (zeige CTBS Antikörper)) repeated session (RS) decreased, while GLT-1 (zeige SLC1A2 Antikörper) increased in cTBS (zeige CTBS Antikörper) SS and cTBS (zeige CTBS Antikörper) RS, compared to control
GLUT1 may play an important role in Prostate Cancer progression via mediating glycolysis and proliferation. There is potential crosstalk between GLUT1-mediated glycolysis and androgen sensitivity in Prostate Cancer.
ARAP2 (zeige ARAP2 Antikörper) knockdown did not affect fatty acid uptake but reduced basal glucose uptake, total levels of the glucose transporter GLUT1, and GLUT1 levels in the plasma membrane and the lipid micro-domain fraction.
TBC1D5 (zeige TBC1D5 Antikörper) shuttling to autophagosomes during metabolic stress facilitates retromer-dependent GLUT1 trafficking.
inhibition of GLUT1 activity and/or expression is shown to impair TGF-beta (zeige TGFB1 Antikörper)-driven fibrogenic processes, including cell proliferation and production of profibrotic mediators
B cell leukemia-induced inhibition of T cell Akt (zeige AKT1 Antikörper)/mTORC1 signaling and glucose metabolism drives T cell dysfunction; metabolic defects included reduced Akt (zeige AKT1 Antikörper)/mammalian target of rapamycin (zeige FRAP1 Antikörper) complex 1 (mTORC1) signaling, decreased expression of the glucose transporter Glut1 and hexokinase 2 (zeige HK2 Antikörper), and reduced glucose uptake
This study demonstrates a strict requirement for GLUT1 in the early stages of mammary tumorigenesis in vitro and in vivo.
GLUT1-dependent glycolysis regulates fibrogenesis in aged lung.
Data (including data from studies using transgenic mice) suggest that Glut1 (glucose transporter type 1) is a critical downstream target of Hif1a (hypoxia-inducible factor 1 (zeige HIF1A Antikörper), alpha subunit (zeige POLG Antikörper)) mediating hyperglycemia-induced extracellular matrix accumulation in kidney via regulation of Nox4 (zeige NOX4 Antikörper) (NADPH oxidase (zeige NOX1 Antikörper) type 4) expression in nephropathy due to diabetes type 1.
Glut-1 expression globally depended on histological subtypes and the staining patterns (diffuse or zonal) were different between thymic carcinomas and type B3 thymomas
Glut-1 glucose transporter expression in esophageal squamous cell carcinoma is associated with tumor aggressiveness.
Glucose transporter 1 transcript levels were higher in the right ventricle than the left ventricle.
pGlcT, together with MEX1, contributes significantly to the export of starch degradation products from chloroplasts in A. thaliana leaves and and that this starch-mediated pathway for photoassimilate export via pGlcT and MEX1 is essential for the growth and development of A. thaliana. [pGlcT]
Low GLUT1 and GLUT3 (zeige SLC2A3 Antikörper) expression in nonclassical monocytes was unaltered during differentiation into macrophages. GLUT4 (zeige SLC2A4 Antikörper) mRNA was only detectable in unstimulated macrophages. Neither monocytes nor macrophages were insulin (zeige INS Antikörper) responsive.
the different conformations of the GLUT-1 transporter in luminal (blood facing) and abluminal (brain facing) membranes of bovine cerebral endothelial cells arise from differential phosphorylation of GLUT-1
Significant increases in GLUT1 gene expression were observed during early lactation.
Hyperthermia-induced Hsp90 (zeige HSP90 Antikörper).eNOS (zeige NOS3 Antikörper) preserves mitochondrial respiration in hyperglycemic endothelial cells by down-regulating Glut-1 and up-regulating G6PD (zeige G6PD Antikörper) activity.
distinct domains of the glucose transporter GLUT1 mediate HTLV envelope binding and virus entry
Expression of GLUT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney.
results suggest that glucose is transported to the axonal cleft intracytoplasmically and delivered to the cleft by GLUT1 transporters
This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
, glucose transporter type 1, erythrocyte/brain
, hepG2 glucose transporter
, human T-cell leukemia virus (I and II) receptor
, solute carrier family 2, facilitated glucose transporter member 1
, solute carrier family 2, member 1
, Solute carrier family 2 a 1 (facilitated glucose transporter) brain
, Solute carrier family 2, facilitated glucose transporter member 1
, solute carrier family 2 (facilitated glucose transporter), member 1
, solute carrier family 2 member 1
, glucose transporter protein
, glucose transporter type 1
, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog
, glucose transport protein