Rekombinanter GLUT1 Antikörper (AA 203-305)

Produktnummer ABIN6940596

Produktdetails anti-GLUT1 Antikörper

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: AA 203-305

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLUT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Spezifität: Recognizes a protein of 55 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary)

Klon: RGLUT1-2476

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: K562, A431, MDA-MB-231 cells or erythrocytes. Mesothelioma or breast, colon and ovarian carcinoma.

Known Application: ELISA (For coating use Ab at 1-2 μg/mL order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GLUT1

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Andere Bezeichnung: SLC2A1 (SLC2A1 Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, Glut-1 antikoerper, Glut1 antikoerper, GLUTB antikoerper, GTG1 antikoerper, Gtg3 antikoerper, RATGTG1 antikoerper, SLC2A1 antikoerper, GLT1 antikoerper, GLUCOSE TRANSPORTER 1 antikoerper, T21H19.70 antikoerper, T21H19_70 antikoerper, plastidic GLC translocator antikoerper, glut1 antikoerper, ped antikoerper, slc2a1 antikoerper, slc2a14 antikoerper, solute carrier family 2 member 1 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 1 antikoerper, plastidic GLC translocator antikoerper, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog antikoerper, SLC2A1 antikoerper, Slc2a1 antikoerper, PGLCT antikoerper, slc2a1.L antikoerper

Molekulargewicht: 55kDa

Gen-ID: 6513

UniProt: P11166

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effekt