Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human AXL Antikörper:
anti-Mouse (Murine) AXL Antikörper:
anti-Rat (Rattus) AXL Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal AXL Primary Antibody für BR, CyTOF - ABIN5012837
Gould, Baxi, Schroeder, Peng, Leadley, Peterson, Perrin: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. in Journal of thrombosis and haemostasis : JTH 2005
Show all 31 Pubmed References
Human Polyclonal AXL Primary Antibody für IHC - ABIN965631
Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: Putative tyrosine kinases expressed in K-562 human leukemia cells. in Proceedings of the National Academy of Sciences of the United States of America 1991
Show all 7 Pubmed References
Human Polyclonal AXL Primary Antibody für IHC - ABIN965632
OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. in Molecular and cellular biology 1991
Show all 7 Pubmed References
Mouse (Murine) Monoclonal AXL Primary Antibody für CyTOF, FACS - ABIN4899408
Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. in Mucosal immunology 2015
Show all 4 Pubmed References
Human Monoclonal AXL Primary Antibody für ELISA, WB - ABIN965629
Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: Towards a proteome-scale map of the human protein-protein interaction network. ... in Nature 2005
Show all 3 Pubmed References
Human Monoclonal AXL Primary Antibody für ELISA, WB - ABIN968973
Budagian, Bulanova, Orinska, Duitman, Brandt, Ludwig, Hartmann, Lemke, Saftig, Bulfone-Paus: Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. in Molecular and cellular biology 2005
Show all 2 Pubmed References
Human Polyclonal AXL Primary Antibody für IHC, IHC (p) - ABIN4282541
Pinato, Mauri, Lloyd, Vaira, Casadio, Boldorini, Sharma: The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma. in British journal of cancer 2013
Show all 2 Pubmed References
Human Monoclonal AXL Primary Antibody für IF, ELISA - ABIN965630
Green, Ikram, Vyas, Patel, Proby, Ghali, Leigh, OToole, Storey: Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours. in British journal of cancer 2006
Show all 2 Pubmed References
Human Monoclonal AXL Primary Antibody für ICC, ELISA - ABIN968974
Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival. in Proceedings of the National Academy of Sciences of the United States of America 2006
Human Monoclonal AXL Primary Antibody für RNAi, ELISA - ABIN560017
Ammoun, Provenzano, Zhou, Barczyk, Evans, Hilton, Hafizi, Hanemann: Axl/Gas6/NF?B signalling in schwannoma pathological proliferation, adhesion and survival. in Oncogene 2014
Findings suggest that METTL3 (zeige METTL3 Antikörper) plays very important oncogenic roles in ovarian carcinoma development and/or aggressiveness by stimulating AXL translation and EMT (zeige ITK Antikörper).
Co-expression of CDCP1 (zeige CDCP1 Antikörper) and AXL is often observed in EGFR (zeige EGFR Antikörper)-mutation-positive tumors, limiting the efficacy of EGFR (zeige EGFR Antikörper) TKIs. Co-treatment with EGFR (zeige EGFR Antikörper) TKI and TPX (zeige TPO Antikörper)-0005 warrants testing.
This study demonstrates that motility behavior of AXL-expressing tumor cells can be elicited by Gas6 (zeige GAS6 Antikörper)-bearing apoptotic bodies generated from tumor treatment with therapeutics that produce killing of a portion of the tumor cells present but not all, hence generating potentially problematic invasive and metastatic behavior of the surviving tumor cells
Results show that average methylation in AXL at birth was associated with higher risk for asthma-related phenotypes in childhood, especially wheezing. The effects of average AXL methylation on wheezing symptoms were magnified in girls compared to boys.
we identified YAP (zeige YAP1 Antikörper)-driven AXL overexpression as a mechanism of resistance to EGFR (zeige EGFR Antikörper) TKIs in lung cancer cells.
The anti-angiogenic effect of luteolin may be associated with the inhibition of the Gas6 (zeige GAS6 Antikörper)/Axl pathway and its downstream phosphatidylinositol 3-kinase (PI3K (zeige PIK3CA Antikörper))/protein kinase B (Akt (zeige AKT1 Antikörper))/mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper)) signaling pathways.
AXL is influenced by p53 (zeige TP53 Antikörper) status and could cause the emergence of aggressive clones after exposure to chemotherapy in colon and breast cancer
Taken together, these findings suggest that AXL most likely serves as an attachment factor for Zika virus on the cell surface, and that productive infection requires endocytosis and delivery of the virus to acidified intracellular compartments.
serum Axl shows high diagnostic accuracy at early stage hepatocellular carcinoma as well as cirrhosis
AXL is the only relevant Zika virus entry cofactor expressed on fetal endothelial cells, and that when produced in mammalian cells, only Zika virus, but not West Nile virus or dengue virus, can use AXL, because it more efficiently binds Gas6 (zeige GAS6 Antikörper).
These results suggest a novel role for Axl in suppressing antigen presentation through MHCI, and enhancing cytokine release, which promotes a suppressive myeloid microenvironment.
AXL is not the key receptor for Zika virus infection using an Axl knockout mouse model.
present findings indicate that MafB (zeige MAFB Antikörper) enhances efferocytosis by regulating Axl expression in RAW264.7 macrophages
Study found that hematopoietic cell-Axl deficiency in Western-type diet-fed Ldlr (zeige LDLR Antikörper)(-/-) mice does not affect the progression of advanced atherosclerosis or lesional processes associated with TAM (zeige CCNA1 Antikörper) receptor signaling.
This study demonstrated that the Gas6 (zeige GAS6 Antikörper)(-/-) Axl(-/-) double knockout (DKO) mice showed axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure.
These results demonstrate that AXL is essential for limiting the immunosuppressive effects of type I interferons and enabling the induction of protective antiviral adaptive immunity.
GAS6 (zeige GAS6 Antikörper)-AXL signaling-mediated autophagy induction in murine macrophages ameliorates hepatic inflammatory responses by inhibiting NLRP3 (zeige NLRP3 Antikörper) inflammasome activation.
Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.
reciprocal activation of Axl and Mer (zeige ERH Antikörper) receptor tyrosine kinases has a major impact on the outcome of renal inflammation.
Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.
activation of receptor tyrosine kinase (zeige RET Antikörper) Axl inhibits the osteogenic differentiation of vascular pericytes.
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
, AXL transforming sequence/gene
, tyrosine-protein kinase receptor UFO
, adhesion-related kinase
, ufo oncogene homolog