Protein Überblick

Cardiolipin hydrolase present at the mitochondrial outer membrane required both for mitochondrial fusion and piRNA metabolic process. Acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting mitochondrial fusion. The production of phosphatidate also regulates the piRNA metabolic process by promoting recruitment and/or activation of components of the meiotic nuage, also named P granule, a critical step for primary biogenesis of piRNAs. Required during spermatogenesis to repress transposable elements and prevent their mobilization via its role in the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).

Alternative names and synonyms associated with PLD6

• phospholipase D family member 6 (PLD6) Antikörper
• phospholipase D family, member 6 (Pld6) Antikörper
• phospholipase D family member 6 S homeolog (pld6.S) Antikörper
• phospholipase D family, member 6 (pld6) Antikörper

• 4933433K01Rik Antikörper
• fc55d08 Antikörper
• Gm10 Antikörper
• mitoPLD Antikörper
• mZuc Antikörper
• Alle Synonyme
• pld6 Antikörper
• wu:fc55d08 Antikörper
• Zuc Antikörper

Bezeichner auf Proteinebene für PLD6

PLD 6 , choline phosphatase 6 , mitoPLD , mitochondrial cardiolipin hydrolase , mitochondrial phospholipase , phosphatidylcholine-hydrolyzing phospholipase D6 , phospholipase D6 , protein zucchini homolog , novel Phospholipase D Active site motif-containing protein , Probable phospholipase D family member FLJ33580 homolog , probable phospholipase D family member FLJ33580 homolog