anti-GALE (GALE) Antikörper

Bezeichnung:: anti-UDP-Galactose-4-Epimerase Antikörper (GALE)

Auf www.antikoerper-online.de finden Sie aktuell 73 UDP-Galactose-4-Epimerase (GALE) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GALE Proteine (30) und GALE Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 115 GALE Produkte verfügbar.

Synonyme:: 1n569, 2310002A12Rik, AI323962, BA5505, BA5700, ECK0748, F15H21.11, F15H21_11, galD, galE, im:7147391, JW0742, REB1, ROOT EPIDERMAL BULGER1, ROOT HAIR DEFECTIVE 1, SDR1E1, SMU.888, UDP-GLUCOSE 4-EPIMERASE, UGE4, VFA0352, wu:fb05f01, xgale, zgc:136578

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	GALE	74246	Q8R059
	GALE	2582	Q14376
	GALE	114860
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-GALE (GALE) Antikörper

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anti-Mouse (Murine) GALE Antikörper:

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Weitere Produktkategorien zu GALE Antikörper

Weitere Antikörper gegen GALE Interaktionspartner

Arabidopsis thaliana UDP-Galactose-4-Epimerase (GALE) Interaktionspartner

This data from this study indicate the importance of UDP-D-galactose synthesis by UGE4 for the organization and function of endomembranes, especially TGN (zeige TG Antikörper)/EEs, which are a sorting station of the secretory and vacuolar pathways.
Rough mapping and whole-genome sequencing identified the mutant with altered localization of NIP5;1 as an allele of UDP-glucose 4-epimerase 4.
RHD1, a UDP-glucose-4-epimerase, is a likely target of root-specific negative regulation by ethylene and that loss of RHD1 function results in a heightened sensitivity of root tissues to both ethylene and auxin. [RHD1]
UGE2 and UGE4 influence growth and cell wall carbohydrate biosynthesis throughout the plant, UGE3 is specialized for pollen development, and UGE1 and UGE5 might act in stress situations.

Mouse (Murine) UDP-Galactose-4-Epimerase (GALE) Interaktionspartner

These studies reveal a new link between hepatic GALE activity and whole-body glucose homeostasis via regulation of hepatic Tff3 (zeige TFF3 Antikörper) expression.
results provide evidence that the Xbp1s/GalE pathway functions as a novel regulatory nexus connecting the UPR to the characteristic postprandial metabolic changes in hepatocytes.

Human UDP-Galactose-4-Epimerase (GALE) Interaktionspartner

Mutation in UDP-galactose-4'-epimerase gene is associated with UDP-galactose-4'-epimerase deficiency.
Data show the protein structure of GALE and its substrate binding and specificity. It is mutated in type III galactosemia. [review]
human UDP-galactose 4'-epimerase stability is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding
These data indicated a critical role of GALE in maintaining cartilage homeostasis, and suggested that GALE inhibition might contribute to OA progress.
GALE variants can be arranged into three groups depending on the severity of enzyme impairment.
Resulst describe the relationship among UDP-galactose 4'-epimerase activity, substrate specificity, metabolic balance, and galactose sensitivity in mammalian cells.
Subtle biochemical and metabolic abnormalities detected in patients expressing these GALE alleles likely reflect, at least in part, the reduced enzymatic activity of the encoded GALE proteins.
Our observations show that altered protein stability is due to misfolding and that loss or reduction of enzyme activity is responsible for the molecular defects underlying GALE-deficiency galactosemia.

GALE Antigen-Profil

Beschreibung des Gens

This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

Alternative names and synonyms associated with GALE

UDP-galactose-4-epimerase (GALE) Antikörper
UDP-galactose-4-epimerase (gale) Antikörper
NAD(P)-binding Rossmann-fold superfamily protein (RHD1) Antikörper
UDP-galactose-4-epimerase (ECs0787) Antikörper
UDP-galactose-4-epimerase (galE) Antikörper
UDP-galactose 4-epimerase GalE (galE) Antikörper
UDP-glucose 4-epimerase (galE1) Antikörper
UDP-glucose 4-epimerase (galE2) Antikörper
UDP-glucose 4-epimerase GalE (galE) Antikörper
UDP-glucose 4-epimerase (STY0809) Antikörper
UDP-glucose 4-epimerase (galE) Antikörper
UDP-glucose/UDP-N-acetylglucosamine 4-epimerase (galE) Antikörper
UDP-glucose 4-epimerase (galE-2) Antikörper
UDP-galactose-4-epimerase (SG0897) Antikörper
UDP-galactose-4-epimerase (galD) Antikörper
UDP-galactose-4-epimerase (Ent638_1250) Antikörper
galactose-4-epimerase, UDP (Gale) Antikörper
UDP-galactose-4-epimerase L homeolog (gale.L) Antikörper
UDP-galactose-4-epimerase (Gale) Antikörper

1n569 Antikörper
2310002A12Rik Antikörper
AI323962 Antikörper
BA5505 Antikörper
BA5700 Antikörper
ECK0748 Antikörper
F15H21.11 Antikörper
F15H21_11 Antikörper
galD Antikörper
galE Antikörper
im:7147391 Antikörper
JW0742 Antikörper
REB1 Antikörper
ROOT EPIDERMAL BULGER1 Antikörper
ROOT HAIR DEFECTIVE 1 Antikörper
SDR1E1 Antikörper
SMU.888 Antikörper
UDP-GLUCOSE 4-EPIMERASE Antikörper
UGE4 Antikörper
VFA0352 Antikörper
wu:fb05f01 Antikörper
xgale Antikörper
zgc:136578 Antikörper

Bezeichner auf Proteinebene für GALE

UDP-galactose-4-epimerase , UDP-glucose 4-epimerase , fb05f01 , UDP-galactose 4-epimerase , galactowaldenase , UDP-glucose (37.7 kD) (1N569) , UDP galactose-4'-epimerase , galactose-4-epimerase, UDP- , short chain dehydrogenase/reductase family 1E, member 1 , galactose-4-epimerase, UDP

GENE ID	SPEZIES
419686	Gallus gallus
456623	Pan troglodytes
678540	Danio rerio
842752	Arabidopsis thaliana
917525	Escherichia coli O157:H7 str. Sakai
945354	Escherichia coli str. K-12 substr. MG1655
957904	Escherichia coli O157:H7 str. EDL933
1028251	Streptococcus mutans UA159
1036650	Escherichia coli CFT073
1067209	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
1085150	Bacillus anthracis str. Ames
1085447	Bacillus anthracis str. Ames
1147990	Yersinia pestis KIM10+
1169457	Shewanella oneidensis MR-1
1173989	Yersinia pestis CO92
1247256	Salmonella enterica subsp. enterica serovar Typhi str. CT18
1252296	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
2687202	Geobacter sulfurreducens PCA
2763289	Yersinia pestis biovar Microtus str. 91001
2883164	Pectobacterium atrosepticum SCRI1043
2955669	Yersinia pseudotuberculosis IP 32953
3103661	Methylococcus capsulatus str. Bath
3231780	Campylobacter jejuni RM1221
3280601	Vibrio fischeri ES114
3728483	Carboxydothermus hydrogenoformans Z-2901
3779874	Shigella boydii Sb227
3868345	Sodalis glossinidius str. 'morsitans'
4714920	Yersinia enterocolitica subsp. enterocolitica 8081
5114212	Enterobacter sp. 638
74246	Mus musculus
380596	Xenopus laevis
2582	Homo sapiens
523154	Bos taurus
114860	Rattus norvegicus
487373	Canis lupus familiaris

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