GALE Antikörper (Middle Region)

Produktnummer ABIN2785691

Produktdetails anti-GALE Antikörper

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GALE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 348 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Andere Bezeichnung: GALE (GALE Produkte)

Synonyme: GALE antikoerper, im:7147391 antikoerper, wu:fb05f01 antikoerper, zgc:136578 antikoerper, F15H21.11 antikoerper, F15H21_11 antikoerper, REB1 antikoerper, ROOT EPIDERMAL BULGER1 antikoerper, ROOT HAIR DEFECTIVE 1 antikoerper, UDP-GLUCOSE 4-EPIMERASE antikoerper, UGE4 antikoerper, ECK0748 antikoerper, galD antikoerper, JW0742 antikoerper, SMU.888 antikoerper, BA5505 antikoerper, BA5700 antikoerper, VFA0352 antikoerper, galE antikoerper, 2310002A12Rik antikoerper, AI323962 antikoerper, 1n569 antikoerper, xgale antikoerper, SDR1E1 antikoerper, UDP-galactose-4-epimerase antikoerper, NAD(P)-binding Rossmann-fold superfamily protein antikoerper, UDP-galactose 4-epimerase GalE antikoerper, UDP-glucose 4-epimerase antikoerper, UDP-glucose 4-epimerase GalE antikoerper, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase antikoerper, galactose-4-epimerase, UDP antikoerper, UDP-galactose-4-epimerase L homeolog antikoerper, GALE antikoerper, gale antikoerper, RHD1 antikoerper, ECs0787 antikoerper, galE antikoerper, galE1 antikoerper, galE2 antikoerper, STY0809 antikoerper, galE-2 antikoerper, SG0897 antikoerper, galD antikoerper, Ent638_1250 antikoerper, Gale antikoerper, gale.L antikoerper

Hintergrund: GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
Alias Symbols: SDR1E1
Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
Protein Size: 348

Molekulargewicht: 38 kDa

Gen-ID: 2582

NCBI Accession: NM_001008216, NP_001008217

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process