GALE Antikörper (AA 1-340)

Produktnummer ABIN5693266

Produktdetails anti-GALE Antikörper

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Bindungsspezifität: AA 1-340

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for GALE detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human GALE recombinant protein (Position: M1-N340).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Andere Bezeichnung: GALE (GALE Produkte)

Synonyme: GALE antikoerper, im:7147391 antikoerper, wu:fb05f01 antikoerper, zgc:136578 antikoerper, F15H21.11 antikoerper, F15H21_11 antikoerper, REB1 antikoerper, ROOT EPIDERMAL BULGER1 antikoerper, ROOT HAIR DEFECTIVE 1 antikoerper, UDP-GLUCOSE 4-EPIMERASE antikoerper, UGE4 antikoerper, ECK0748 antikoerper, galD antikoerper, JW0742 antikoerper, SMU.888 antikoerper, BA5505 antikoerper, BA5700 antikoerper, VFA0352 antikoerper, galE antikoerper, 2310002A12Rik antikoerper, AI323962 antikoerper, 1n569 antikoerper, xgale antikoerper, SDR1E1 antikoerper, UDP-galactose-4-epimerase antikoerper, NAD(P)-binding Rossmann-fold superfamily protein antikoerper, UDP-galactose 4-epimerase GalE antikoerper, UDP-glucose 4-epimerase antikoerper, UDP-glucose 4-epimerase GalE antikoerper, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase antikoerper, galactose-4-epimerase, UDP antikoerper, UDP-galactose-4-epimerase L homeolog antikoerper, GALE antikoerper, gale antikoerper, RHD1 antikoerper, ECs0787 antikoerper, galE antikoerper, galE1 antikoerper, galE2 antikoerper, STY0809 antikoerper, galE-2 antikoerper, SG0897 antikoerper, galD antikoerper, Ent638_1250 antikoerper, Gale antikoerper, gale.L antikoerper

Hintergrund:

Synonyms: UDP-glucose 4-epimerase

Background: The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process