RASA1 Produkte
(RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
Kategorien
The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq, May 2012].
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Ausgewählte RASA1 Kategorien
RASA1 Antikörper
High quality antibodies with extensive validation data.
RASA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RASA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RASA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN562592
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Chicken, Dog, Frog, Human, Mouse, Rat
Applikation
WB, IHC, IF, IP
Validierungen
- (5)
- (4)
Kat. Nr.
ABIN967706
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN519660
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene RASA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Goat
Analytical Method
Competition ELISA
Validierungen
Kat. Nr.
ABIN995296
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Chicken
Analytical Method
Competition ELISA
Validierungen
Kat. Nr.
ABIN1057985
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1154493
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RASA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317464
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317466
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094933
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RASA1 Produkten
: "Eph-B4 prevents venous adaptive remodeling in the adult arterial environment." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 561-75, (2011) (PubMed).: "Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor." in: Genes & development, Vol. 17, Issue 4, pp. 449-54, (2003) (PubMed).
: "Annexin V inhibits the 12-O-tetradecanoylphorbol-13-acetate-induced activation of Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of Shc in MCF-7 cells." in: Oncogene, Vol. 19, Issue 25, pp. 2904-12, (2000) (PubMed).
: "Formation of complexes involving RasGAP and p190 RhoGAP during morphogenetic events of the gastrulation in xenopus." in: European journal of biochemistry / FEBS, Vol. 265, Issue 2, pp. 530-8, (1999) (PubMed).
: "PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex." in: Cell, Vol. 61, Issue 1, pp. 125-33, (1990) (PubMed).
: "PDGF induction of tyrosine phosphorylation of GTPase activating protein." in: Nature, Vol. 342, Issue 6250, pp. 711-4, (1990) (PubMed).
Synonyme und alternative Namen zu RASA1
vacuolar peduncle (vap), RAS p21 protein activator 1 (RASA1), RAS p21 protein activator 1 (Rasa1), CG9209, CM-AVM, CMAVM, D-RasGAP, Dmel\\CG9209, GAP, Gap, GAPX, p120GAP, p120RASGAP, PKWS, RAS-GAP, RASA, Rasa, RasGAP, RasGap, rasGap, RASGAPBezeichner auf Proteinebene für RASA1
- CG9209-PA
- CG9209-PB
- CG9209-PC
- CG9209-PD
- Ras GTPase-activating protein
- vacuolar peduncule
- vacuolar pedunculi
- vap-PA
- vap-PB
- vap-PC
- vap-PD
- ras GTPase-activating protein 1
- triphosphatase-activating protein
- GAP
- GTPase-activating protein
- RAS p21 protein activator (GTPase activating protein RAS p21)
- p120GAP
- rasGAP
- RAS p21 protein activator 1
- p120-rasGAP
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