RAPGEF2 Produkte
(Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
Kategorien
Members of the RAS (see HRAS\; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008].
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Ausgewählte RAPGEF2 Kategorien
RAPGEF2 Antikörper
High quality antibodies with extensive validation data.
RAPGEF2 ELISA Kits
Reliable ELISA kits for a wide range of species.
RAPGEF2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RAPGEF2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN564181
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Applikation
WB
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6746202
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN2775568
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RAPGEF2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN510241
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RAPGEF2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317410
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3095077
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136471
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RAPGEF2 Produkten
: "Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP." in: The Journal of biological chemistry, Vol. 291, Issue 41, pp. 21584-21595, (2016) (PubMed).: "Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells." in: Science signaling, Vol. 6, Issue 281, pp. ra51, (2013) (PubMed).
: "NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro." in: PLoS ONE, Vol. 8, Issue 12, pp. e82789, (2013) (PubMed).
: "Rap2A links intestinal cell polarity to brush border formation." in: Nature cell biology, Vol. 14, Issue 8, pp. 793-801, (2012) (PubMed).
: "Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control." in: Cellular signalling, Vol. 23, Issue 12, pp. 2056-64, (2011) (PubMed).
: "PKC-theta selectively controls the adhesion-stimulating molecule Rap1." in: Blood, Vol. 112, Issue 12, pp. 4617-27, (2008) (PubMed).
: "Isoform diversity of dystrobrevin, the murine 87-kDa postsynaptic protein." in: The Journal of biological chemistry, Vol. 271, Issue 13, pp. 7802-10, (1996) (PubMed).
Synonyme und alternative Namen zu RAPGEF2
Rap guanine nucleotide exchange factor 2 (RAPGEF2), Rap guanine nucleotide exchange factor 2 L homeolog (rapgef2.L), Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2), Rap guanine nucleotide exchange factor (GEF) 2 (rapgef2), Rap guanine nucleotide exchange factor 2 (rapgef2), Rap guanine nucleotide exchange factor (GEF) 2 (Rapgef2), Rap guanine nucleotide exchange factor 2 (Rapgef2), 5830453M24Rik, CNrasGEF, CNRasGEF, fa11h07, MGC83978, mKIAA0313, NRAPGEP, nRap GEP, nRapGEP, PDZ-GEF1, PDZGEF1, Pdzgef1, RA-GEF, RA-GEF-1, Rap-GEP, RAPGEF2, wu:fa11h07Bezeichner auf Proteinebene für RAPGEF2
- Rap guanine nucleotide exchange factor (GEF) 2
- rap guanine nucleotide exchange factor 2
- Rap guanine nucleotide exchange factor 2-like
- rap guanine nucleotide exchange factor 2-like
- PDZ domain containing guanine nucleotide exchange factor (GEF) 1
- PDZ domain-containing guanine nucleotide exchange factor 1
- RA(Ras/Rap1A-associating)-GEF
- neural RAP guanine nucleotide exchange protein
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