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RAPTOR Produkte

(RAPTOR)

Kategorien

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Ausgewählte RAPTOR Kategorien

RAPTOR Antikörper

High quality antibodies with extensive validation data.

Empfohlene RAPTOR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, DB, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN389879
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN3032434
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
Kat. Nr. ABIN700780
Menge 100 μL
Datenblatt Datenblatt

Neueste Publikationen zu unseren RAPTOR Produkten

Cully, Genevet, Warne, Treins, Liu, Bastien, Baum, Tapon, Leevers, Downward: "A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1." in: Molecular and cellular biology, Vol. 30, Issue 2, pp. 481-95, (2009) (PubMed).

Wang, Bai, Qin, Zhang, Yi, Teesdale, Zhao, Pober, Tellides: "Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation." in: Circulation research, Vol. 101, Issue 6, pp. 560-9, (2007) (PubMed).

Chu, Rajamanonmani, Li, Bhuvanakantham, Lescar, Ng: "Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein." in: The Journal of general virology, Vol. 86, Issue Pt 2, pp. 405-12, (2005) (PubMed).

Kim, Sarbassov, Ali, King, Latek, Erdjument-Bromage, Tempst, Sabatini: "mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery." in: Cell, Vol. 110, Issue 2, pp. 163-75, (2002) (PubMed).

Hara, Maruki, Long, Yoshino, Oshiro, Hidayat, Tokunaga, Avruch, Yonezawa: "Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action." in: Cell, Vol. 110, Issue 2, pp. 177-89, (2002) (PubMed).

Synonyme und alternative Namen zu RAPTOR

regulatory associated protein of MTOR complex 1 (RPTOR), regulatory associated protein of MTOR, complex 1 (Rptor), 4932417H02Rik, KOG1, Mip1, mKIAA1303, Rap, Raptor, RGD1311784

Bezeichner auf Proteinebene für RAPTOR

  • p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats
  • raptor
  • regulatory-associated protein of mTOR
  • p150 target of rapamycin (TOR)-scaffold protein
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