Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RASA1 Antikörper

RASA1 Reaktivität: Human, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7245677
  • Target Alle RASA1 Antikörper anzeigen
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    Reaktivität
    • 48
    • 30
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 70
    • 8
    • 1
    Kaninchen
    Klonalität
    • 72
    • 7
    Polyklonal
    Konjugat
    • 31
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RASA1 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 31
    • 26
    • 26
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human RASA1
    Isotyp
    IgG
    Top Product
    Discover our top product RASA1 Primärantikörper
  • Applikationshinweise
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    Andere Bezeichnung
    RASA1 (RASA1 Produkte)
    Synonyme
    CG9209 antikoerper, D-RasGAP antikoerper, Dmel\\CG9209 antikoerper, RAS-GAP antikoerper, RasGAP antikoerper, RasGap antikoerper, rasGap antikoerper, CM-AVM antikoerper, CMAVM antikoerper, GAP antikoerper, PKWS antikoerper, RASA antikoerper, RASGAP antikoerper, p120GAP antikoerper, p120RASGAP antikoerper, GAPX antikoerper, Rasa antikoerper, Gap antikoerper, vacuolar peduncle antikoerper, RAS p21 protein activator 1 antikoerper, vap antikoerper, RASA1 antikoerper, Rasa1 antikoerper
    Hintergrund
    The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
    UniProt
    P20936
    Pathways
    Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Sie sind hier:
Kundenservice